Impact of pharmacist-led home medicines review services on drug-related problems among the elderly population: a systematic review
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OBJECTIVES: To address and elucidate the impact of pharmacist-led home medicines review (HMR) services on identifying drug-related problems (DRPs) among the elderly population in home care settings. METHODS: A comprehensive systematic search was performed using electronic scientific databases such as PubMed, Scopus, Embase, and Web of Science for studies published between January 1, 2008 and December 31, 2018, pertaining to HMR services by pharmacists for identifying DRPs. RESULTS: In total, 4,292 studies were retrieved from the searches, of which 24 were excluded as duplicates. Titles and abstracts were screened for the remaining 4,268 studies, of which 4,239 were excluded due to the extraneous nature of the titles and/or abstracts. Subsequently, 29 full-text articles were assessed, and 19 were removed for lacking the outcome of interest and/or not satisfying the study’s inclusion criteria. Finally, 10 studies were included in the review; however, publication bias was not assessed, which is a limitation of this study. In all studies, pharmacists identified a highly significant amount of DRPs through HMR services. The most common types of DRPs were potential drug-drug interactions, serious adverse drug reactions, need for an additional drug, inappropriate medication use, non-adherence, untreated indications, excessive doses, and usage of expired medications. CONCLUSIONS: HMR is a novel extended role played by pharmacists. The efficiency of such programs in identifying and resolving DRPs could minimize patients’ health-related costs and burden, thereby enhancing the quality of life and well-being among the elderly.
Abstract
OBJECTIVES: To address and elucidate the impact of pharmacist-led home medicines review (HMR) services on identifying drug-related problems (DRPs) among the elderly population in home care settings. METHODS: A comprehensive systematic search was performed using electronic scientific databases such as PubMed, Scopus, Embase, and Web of Science for studies published between January 1, 2008 and December 31, 2018, pertaining to HMR services by pharmacists for identifying DRPs. RESULTS: In total, 4,292 studies were retrieved from the searches, of which 24 were excluded as duplicates. Titles and abstracts were screened for the remaining 4,268 studies, of which 4,239 were excluded due to the extraneous nature of the titles and/or abstracts. Subsequently, 29 full-text articles were assessed, and 19 were removed for lacking the outcome of interest and/or not satisfying the study’s inclusion criteria. Finally, 10 studies were included in the review; however, publication bias was not assessed, which is a limitation of this study. In all studies, pharmacists identified a highly significant amount of DRPs through HMR services. The most common types of DRPs were potential drug-drug interactions, serious adverse drug reactions, need for an additional drug, inappropriate medication use, non-adherence, untreated indications, excessive doses, and usage of expired medications. CONCLUSIONS: HMR is a novel extended role played by pharmacists. The efficiency of such programs in identifying and resolving DRPs could minimize patients’ health-related costs and burden, thereby enhancing the quality of life and well-being among the elderly.
참고문헌 (35)
- Hajjar ER, "Polypharmacy in elderly patients", Am J Geriatr Pharmacother, 5, pp.345~351 (2007)
- Castelino RL, "Retrospective evaluation of home medicines review by pharmacists in older Australian patients using the medication appropriateness index", Ann Pharmacother, 44, pp.1922~1929 (2010)
- Gilbert AL, "Collaborative medication management services : improving patient care", Med J Aust, 177, pp.189~192 (2002)
- Willis JS, "In-home medication reviews : a novel approach to improving patient care through coordination of care", J Community Health, 36, pp.1027~1031 (2011)
- Ahn J, "Understanding, benefits and difficulties of home medicines review-patients’ perspectives", Aust Fam Physician, 44, pp.249~253 (2015)
- Dhillon AK, "General practitioners’ perceptions on home medicines reviews : a qualitative analysis", BMC Fam Pract, 16, pp.16~ (2015)
- Ouzzani M, "Rayyan—a web and mobile app for systematic reviews", Syst Rev, 5, pp.210~ (2016)
- Kmet LM, "Standard quality assessment criteria for evaluating primary research papers from a variety of fields", Edmonton: Alberta Heritage Foundation for Medical Research, pp.1~22 (2004)
- Castelino RL, "Are interventions recommended by pharmacists during home medicines review evidence‐based?", J Eval Clin Pact, 17, pp.104~110 (2011)
- Elliott RA, "Pharmacist-led medication review to identify medication-related problems in older people referred to an Aged Care Assessment Team : a randomized comparative study", Drugs Aging, 29, pp.593~605 (2012)
- Nishtala PS, "A retrospective study of drug‐related problems in Australian aged care homes : medication reviews involving pharmacists and general practitioners", J Eval Clin Pract, 17, pp.97~103 (2011)
- Gheewala PA, "Impact of the pharmacist medication review services on drug-related problems and potentially inappropriate prescribing of renally cleared medications in residents of aged care facilities", Drugs Aging, 31, pp.825~835 (2014)
- Lenander C, "Effects of medication reviews on use of potentially inappropriate medications in elderly patients; a cross-sectional study in Swedish primary care", BMC Health Serv Res, 18, pp.616~ (2018)
- Chandrasekhar D, "Role of pharmacist led home medication review in community setting and the preparation of medication list", Clin Epidemiol Glob Health, 7, pp.66~70 (2019)
- Papastergiou J, "Home medication reviews by community pharmacists : reaching out to homebound patients", Can Pharm J, 146, pp.139~142 (2013)
- Basheti IA, "Treatment related problems for outpatients with chronic diseases in Jordan : the value of home medication reviews", Int J Clin Pharm, 35, pp.92~100 (2013)
- Fiss T, "Detection of drug related problems in an interdisciplinary health care model for rural areas in Germany", Pharm World Sci, 32, pp.566~574 (2010)
- Cheen MH, "Evaluation of a care transition program with pharmacist-provided home-based medication review for elderly Singaporeans at high risk of readmissions", Int J Qual Health Care, 29, pp.200~205 (2017)
- Quirke J, "Home medicines reviews-do they change prescribing and patient", pharmacist acceptance?, 2006, pp.35, 266~267
- Elina AN, "The impact of home medication review in patients with type 2 diabetes mellitus living in rural areas of Kuantan, Malaysia", Value Health, 17, pp.A127~ (2014)
- Srinivas B, "Betterment of patient to get optimal health outcomes through home medicines review(HMR)", Int J Pharm Res Allied Sci, 3, pp.10~16 (2014)
- Mishra A, "Impact of pharmacist–psychiatrist collaborative patient education on medication adherence and quality of life(QOL)of Bipolar Affective Disorder(BPAD)patients", Front Pharmacol, 8, pp.722~ (2017)
- Mishra A, "Impact of pharmacist-led collaborative patient education on medication adherence and quality of life of schizophrenia patients in a tertiary care setting", Bull Fac Pharm Cairo Univ, 55, pp.345~349 (2017)
- Gudi SK, "Assessment of knowledge, attitude and perceptions of HIV", AIDS among secondary school students in Guntur district of south India : a cross-sectional survey, 2018, pp.4, 87~92
- Sai Krishna Gudi, "Assessment of the impact of pharmacist-led face-to-face counselling on HIV", AIDS among school & college going students, and infected patients in south India, 2019, pp.7(4), 592~595[DOI]
- Turner JP, "Implementation of pharmacist-led medication reviews in general practice", Int J Clin Pharm, 35, pp.3~4 (2013)
- White L, "Consumer perspectives of the Australian Home Medicines Review Program : benefits and barriers", Res Social Adm Pharm, 8, pp.4~16 (2012)
- Holland R, "Does pharmacist‐led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta‐analysis", Br J Clin Pharmacol, 65, pp.303~316 (2008)
- Pacini M, "Home-based medication review in older people : is it cost effective?", Pharmacoeconomics, 25, pp.171~180 (2007)
- Carter SR, "Home medicines reviews : a quantitative study of the views of recipients and eligible non-recipients", Int J Pharm Pract, 20, pp.209~217 (2012)
- Carter SR, "The willingness of informal caregivers to assist their care-recipient to use home medicines review", Health Expect, 19, pp.527~542 (2016)
- Steele KM, "Home-based comprehensive medication reviews : pharmacist’s impact on drug therapy problems in geriatric patients", Consult Pharm, 31, pp.598~605 (2016)
- Alderman CP, "Medication-related problems identified in home medicines reviews conducted in an Australian rural setting", Consult Pharm, 28, pp.432~442 (2013)
- Vink J, "Pharmacist identification of medication-related problems in the home care setting", Consult Pharm, 26, pp.477~484 (2011)
- Stuijt CC, "Appropriateness of prescribing among elderly patients in a Dutch residential home : observational study of outcomes after a pharmacist-led medication review", Drugs Aging, 25, pp.947~954 (2008)