본문 바로가기
KERD
논문KCI 등재

Epidemiological characteristics of and containment measures for COVID-19 in Busan, Korea

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

OBJECTIVES: To describe and evaluate epidemiological investigation results and containment measures implemented in Busan, where 108 cases were confirmed with coronavirus disease 2019 (COVID-19) between February 21, 2020 and March 24, 2020. METHODS: Any individual who tested positive for COVID-19 was classified as a confirmed case. Measures were taken to identify the source of infection and trace and quarantine contacts. Serial intervals were estimated and the effective reproduction number was computed. RESULTS: Of the total 18,303 COVID-19 tests performed between January 16, 2020 and March 24, 2020 in Busan, 108 yielded positive results (positive test rate, 0.6%). All confirmed cases were placed in isolation at hospitals. Of the 108 confirmed cases, 59 (54.6%) were female. The most common age group was 20-29 years with 37 cases (34.3%). Regarding symptoms at the time of diagnosis, cough (n=38, 35.2%) and fever (n=34, 31.5%) were most common; 12 cases (11.1%) were asymptomatic. The source of infection was identified in 99 cases (91.7%). A total of 3,223 contacts were identified and quarantined. Household contacts accounted for 196, and the household secondary attack rate was 8.2% (95% confidence interval [CI], 4.7 to 12.9). The mean serial interval was estimated to be 5.54 days (95% CI, 4.08 to 7.01). After February 26, (Rt) remained below 1 in Busan. CONCLUSIONS: The early containment strategy implemented in Busan shows that control is possible if outbreaks are of limited scope. In preparation for future outbreaks, public health and healthcare systems should be re-examined and put in a ready state.

Abstract

OBJECTIVES: To describe and evaluate epidemiological investigation results and containment measures implemented in Busan, where 108 cases were confirmed with coronavirus disease 2019 (COVID-19) between February 21, 2020 and March 24, 2020. METHODS: Any individual who tested positive for COVID-19 was classified as a confirmed case. Measures were taken to identify the source of infection and trace and quarantine contacts. Serial intervals were estimated and the effective reproduction number was computed. RESULTS: Of the total 18,303 COVID-19 tests performed between January 16, 2020 and March 24, 2020 in Busan, 108 yielded positive results (positive test rate, 0.6%). All confirmed cases were placed in isolation at hospitals. Of the 108 confirmed cases, 59 (54.6%) were female. The most common age group was 20-29 years with 37 cases (34.3%). Regarding symptoms at the time of diagnosis, cough (n=38, 35.2%) and fever (n=34, 31.5%) were most common; 12 cases (11.1%) were asymptomatic. The source of infection was identified in 99 cases (91.7%). A total of 3,223 contacts were identified and quarantined. Household contacts accounted for 196, and the household secondary attack rate was 8.2% (95% confidence interval [CI], 4.7 to 12.9). The mean serial interval was estimated to be 5.54 days (95% CI, 4.08 to 7.01). After February 26, (Rt) remained below 1 in Busan. CONCLUSIONS: The early containment strategy implemented in Busan shows that control is possible if outbreaks are of limited scope. In preparation for future outbreaks, public health and healthcare systems should be re-examined and put in a ready state.

참고문헌 (32)

  1. "Coronavirus disease 2019 (COVID-19): situation report"[URL]
  2. "Press release: the updates on COVID-19 in Korea as of 31 March"[URL]
  3. 기모란, "Epidemiologic characteristics of early cases with 2019 novel coronavirus (2019-nCoV) disease in Korea", Epidemiology and Health, 42, pp.1~7 (2020), 한국역학회[DOI]
  4. COVID-19 National Emergency Response Center, "Coronavirus Disease-19: The First 7,755 Cases in the Republic of Korea", Osong Public Health and Research Perspectives, 11(2), pp.85~90 (2020), 질병관리청[DOI]
  5. Akhmetzhanov AR, "Analyzing and forecasting the Ebola incidence in North Kivu, the Democratic Republic of the Congo from 2018-19 in real time", Epidemics, 27, pp.123~131 (2019)
  6. Shim E, "Transmission potential and severity of COVID-19 in South Korea", Int J Infect Dis, 93, pp.339~344 (2020)
  7. Thompson RN, "Improved inference of time-varying reproduction numbers during infectious disease outbreaks", Epidemics, 29, pp.100356~ (2019)
  8. Cori A, "A new framework and software to estimate time-varying reproduction numbers during epidemics", Am J Epidemiol, 178, pp.1505~1512 (2013)
  9. Dalziel BD, "Unreported cases in the 2014-2016 Ebola epidemic : spatiotemporal variation, and implications for estimating transmission", PLoS Negl Trop Dis, 12, pp.e0006161~ (2018)
  10. Tognotti E, "Lessons from the history of quarantine, from plague to influenza A", Emerg Infect Dis, 19, pp.254~259 (2013)
  11. Gensini GF, "The concept of quarantine in history : from plague to SARS", J Infect, 49, pp.257~261 (2004)
  12. Klinkenberg D, "The effectiveness of contact tracing in emerging epidemics", PLoS One, 1, pp.e12~ (2006)
  13. Hellewell J, "Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts", Lancet Glob Health, 8, pp.e488~e496 (2020)
  14. Anderson RM, "How will country-based mitigation measures influence the course of the COVID-19 epidemic?", Lancet, 395, pp.931~934 (2020)
  15. Kucharski AJ, "Early dynamics of transmission and control of COVID-19 : a mathematical modelling study", Lancet Infect Dis, 20, pp.553~558 (2020)
  16. "Report 9: impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand" (2020)[URL]
  17. Kim SW, "Risk factors for transmission of Middle East respiratory syndrome coronavirus infection during the 2015 outbreak in South Korea", Clin Infect Dis, 64, pp.551~557 (2017)
  18. 천병철, "Understanding and Modeling the Super-spreading Events of the Middle East Respiratory Syndrome Outbreak in Korea", Infection and Chemotherapy, 48(2), pp.147~149 (2016), 대한감염학회
  19. Korea Centers for Disease Control and Prevention, "Coronavirus Disease-19: Summary of 2,370 Contact Investigations of the First 30 Cases in the Republic of Korea", Osong Public Health and Research Perspectives, 11(2), pp.81~84 (2020), 질병관리청[DOI]
  20. He X, "Temporal dynamics in viral shedding and transmissibility of COVID-19", Nat Med, 26, pp.672~675 (2020)
  21. Yu P, "A familial cluster of infection associated with the 2019 novel coronavirus indicating possible person-to-person transmission during the incubation period", J Infect Dis, 221, pp.1757~1761 (2020)
  22. Park SY, "Coronavirus disease outbreak in call center, South Korea", Emerg Infect Dis (2020)[DOI]
  23. Lloyd-Smith JO, "Curtailing transmission of severe acute respiratory syndrome within a community and its hospital", Proc Biol Sci, 270, pp.1979~1989 (2003)
  24. Ranney ML, "Critical supply shortages-the need for ventilators and personal protective equipment during the COVID-19 pandemic", N Engl J Med, 382, pp.e41~ (2020)
  25. Hick JL, "Novel coronavirus and old lessons-preparing the health system for the pandemic", N Engl J Med, 382, pp.e55~ (2020)
  26. Keeling MJ, "The efficacy of contact tracing for the containment of the 2019 novel coronavirus(COVID-19)", medRxiv 2020. doi: https:, doi.org, pp.10.1101, 2020.02.14.20023036[DOI]
  27. Frieden TR, "Identifying and interrupting superspreading events-implications for control of severe acute respiratory syndrome coronavirus 2", Emerg Infect Dis, 26, pp.1059~1066 (2020)
  28. Rosenbaum L, "Facing COVID-19 in Italy-ethics, logistics, and therapeutics on the epidemic’s front line", N Engl J Med, 382, pp.1873~ (2020)
  29. Dichter JR, "System-level planning, coordination, and communication : care of the critically ill and injured during pandemics and disasters : CHEST consensus statement", Chest, 146(4 Suppl), pp.e87S~e102S (2014)
  30. Hick JL, "Surge capacity principles : care of the critically ill and injured during pandemics and disasters : CHEST consensus statement", Chest, 146(4 Suppl), pp.e1S~e16S (2014)
  31. King MA, "Evacuation of the ICU : care of the critically ill and injured during pandemics and disasters : CHEST consensus statement", Chest, 146(4 Suppl), pp.e44S~e60S (2014)
  32. Armon BD, "Legal considerations when making a practice change", Chest, 146, pp.215~219 (2014)

관련 논문AI추천

이 간행물의 다른 논문 (73건)