Characteristics of imported and domestic malaria cases in Gyeonggi Province, Republic of Korea
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OBJECTIVES: This study explored 11 years of malaria data from mandatory reporting in Gyeonggi Province, Korea, to provide information for prevention strategies by linkage to nationwide health claims data. METHODS: Reported malaria cases in Gyeonggi Province from 2011 to 2021 were linked to medical usage data from the National Health Insurance Database. Data about hospitalization, antibiotic prescription and duration, malarial species, and sociodemographic information of the cases were included. RESULTS: Between 2011 and 2021, a total of 3,011 malaria cases were reported, consisting of 2,828 domestic (93.9%) and 183 imported (6.1%) cases. Over 80% of the cases involved males, with the majority of patients being in their 20s. Both domestic and imported cases peaked between June and August over the years. Imported cases had a higher hospitalization rate (66.9%) compared to domestically-acquired cases (54.9%). There was a significant variation in treatment rates, with 80.7% of imported cases and 74.6% of domestic cases receiving treatment. For domestic cases, chloroquine combined with primaquine was the most commonly prescribed treatment (77.0%), while atovaquone-proguanil was frequently used for imported cases (25.9%). Plasmodium vivax was the predominant species in domestic cases (94.9%), whereas P. malariae was more common in imported cases (62.3%). The overall number of reported malaria cases declined following a sharp decrease in imported cases in 2020 and 2021. CONCLUSIONS: Despite a decreasing trend in malaria cases reported in Gyeonggi Province, imported cases exhibited higher hospitalization rates and different antibiotic prescription and treatment patterns, reflecting the presence of a different malarial species.
Abstract
OBJECTIVES: This study explored 11 years of malaria data from mandatory reporting in Gyeonggi Province, Korea, to provide information for prevention strategies by linkage to nationwide health claims data. METHODS: Reported malaria cases in Gyeonggi Province from 2011 to 2021 were linked to medical usage data from the National Health Insurance Database. Data about hospitalization, antibiotic prescription and duration, malarial species, and sociodemographic information of the cases were included. RESULTS: Between 2011 and 2021, a total of 3,011 malaria cases were reported, consisting of 2,828 domestic (93.9%) and 183 imported (6.1%) cases. Over 80% of the cases involved males, with the majority of patients being in their 20s. Both domestic and imported cases peaked between June and August over the years. Imported cases had a higher hospitalization rate (66.9%) compared to domestically-acquired cases (54.9%). There was a significant variation in treatment rates, with 80.7% of imported cases and 74.6% of domestic cases receiving treatment. For domestic cases, chloroquine combined with primaquine was the most commonly prescribed treatment (77.0%), while atovaquone-proguanil was frequently used for imported cases (25.9%). Plasmodium vivax was the predominant species in domestic cases (94.9%), whereas P. malariae was more common in imported cases (62.3%). The overall number of reported malaria cases declined following a sharp decrease in imported cases in 2020 and 2021. CONCLUSIONS: Despite a decreasing trend in malaria cases reported in Gyeonggi Province, imported cases exhibited higher hospitalization rates and different antibiotic prescription and treatment patterns, reflecting the presence of a different malarial species.
참고문헌 (27)
- Chai JY, "History and current status of malaria in Korea", Infect Chemother, 52, pp.441~452 (2020)[DOI]
- "World malaria report 2022"[URL]
- "Mandatory reporting infectious disease"[URL]
- Armed Forces Health Surveillance Division, "Malaria among members of the U. S. Armed Forces, 2013-2022", MSMR, 30, pp.10~15 (2023)
- Olani Z, "A five-year(2016-2020)trend analysis of Malaria surveillance data in Oromia Regional State, Ethiopia", Biomed Res Int, 2023, pp.5278839~ (2023)[DOI]
- Ocen E, "Severe malaria burden, clinical spectrum and outcomes at Apac district hospital, Uganda : a retrospective study of routine health facility-based data", Malar J, 22, pp.325~ (2023)[DOI]
- Park S, "National Infectious Diseases Surveillance data of South Korea", Epidemiol Health, 36, pp.e2014030~ (2014)[DOI]
- "Population of Gyeonggi Province, South Korea from 1970 to 2023 (in millions)"[URL]
- Lee J, "Cohort profile : the National Health Insurance Service-National Sample Cohort(NHIS-NSC), South Korea", Int J Epidemiol, 46, pp.e15~ (2017)[DOI]
- "Malaria control guideline" (2023)[URL]
- "2015 Malaria outbreak status and characteristics in Gyeonggi-do"[URL]
- Kim HJ, "Status of malaria and diagnosis rate in the Republic of Korea, 2018-2022", Public Health Wkly Rep, 16, pp.852~866 (2023)[DOI]
- Kwon RH, "Associations between conventional healthy behaviors and social distancing during the COVID-19 pandemic : evidence from the 2020 Community Health Survey in Korea", J Prev Med Public Health, 55, pp.568~577 (2022)[DOI]
- "The malaria treatment guidelines" (2023)[URL]
- Castro MC, "Malaria transmission and prospects for malaria eradication : the role of the environment", Cold Spring Harb Perspect Med, 7, pp.a025601~ (2017)[DOI]
- Kim HS, "Cost-benefit analysis of malaria chemoprophylaxis and early diagnosis for Korean soldiers in malaria risk regions", J Korean Med Sci, 33, pp.e59~ (2018)[DOI]
- Bahk YY, "Epidemiological characteristics of re-emerging vivax malaria in the Republic of Korea(1993-2017)", Korean J Parasitol, 56, pp.531~543 (2018)[DOI]
- Adams JH, "The biology of Plasmodium vivax", Cold Spring Harb Perspect Med, 7, pp.a025585~ (2017)[DOI]
- Kim HC, "Malaria in the Republic of Korea, 1993-2007. Variables related to re-emergence and persistence of Plasmodium vivax among Korean populations and U. S. forces in Korea", Mil Med, 174, pp.762~769 (2009)[DOI]
- Kim TS, "Decreasing incidence of Plasmodium vivax in the Republic of Korea during 2010-2012", Malar J, 12, pp.309~ (2013)[DOI]
- Oriero EC, "Plasmodium malariae, current knowledge and future research opportunities on a neglected malaria parasite species", Crit Rev Microbiol, 47, pp.44~56 (2021)[DOI]
- "Malaria management"[URL]
- Im JH, "Severe Plasmodium vivax infection in Korea", Malar J, 16, pp.51~ (2017)[DOI]
- Kim SJ, "The long and short incubation periods of Plasmodium vivax malaria in Korea : the characteristics and relating factors", Infect Chemother, 45, pp.184~193 (2013)[DOI]
- Lee KS, "Short report : chloroquine-resistant Plasmodium vivax in the Republic of Korea", Am J Trop Med Hyg, 80, pp.215~217 (2009)
- Halani S, "Weight-related malaria treatment failure with artemether-lumefantrine", J Travel Med, 30, pp.taad036~ (2023)[DOI]
- Ku B, "Status of follow-up diagnosis after treatment of malaria patients in Republic of Korea, 2014-2020", Public Health Wkly Rep, 14, pp.2441~2443 (2021)