The associations of cardiovascular and lifestyle factors with mortality from chronic kidney disease as the underlying cause: the JACC study
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OBJECTIVES: This study investigated conventional cardiovascular and lifestyle risk factors affecting mortality from chronic kidney disease as the underlying cause in the general Japanese population.METHODS: We conducted an 18.8-year follow-up study of 44,792 men and 61,522 women aged 40-79 from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk between 1986 and 1990. Cox proportional hazard models were used to analyze the association between risk factors and mortality from chronic kidney disease.RESULTS: During the follow-up period, 373 participants (185 men and 188 women) died from chronic kidney disease. A body mass index of ≥27.0 kg/m2 (hazard ratio [HR], 2.00; 95% confidence interval [CI], 1.19 to 3.36 for men and HR, 1.91; 95% CI, 1.19 to 3.07 for women, compared with 23.0-24.9 kg/m2), a history of hypertension (HR, 2.32; 95% CI, 1.67 to 3.22 for men and HR, 2.01; 95% CI, 1.44 to 2.81 for women) and a history of diabetes mellitus (HR, 5.21; 95% CI, 3.68 to 7.37 for men and HR, 7.10; 95% CI, 4.93 to 10.24 for women) were associated with an increased risk of mortality from chronic kidney disease in both genders. In men, smoking was also associated with an increased risk (HR, 1.91; 95% CI, 1.25 to 2.90), while current drinking (HR, 0.58; 95% CI, 0.34 to 0.98 for <23 g/day; HR, 0.48; 95% CI, 0.29 to 0.80 for 23-45 g/day and HR, 0.53; 95% CI, 0.32 to 0.86 for ≥46 g/day) and exercising ≥5 hr/wk (HR, 0.42; 95% CI, 0.18 to 0.96) were associated with a lower risk. Similar but non-significant associations for smoking and drinking were observed in women.CONCLUSIONS: In addition to a history of hypertension and a history of diabetes mellitus, body mass index, smoking status, drinking status, and exercise habits were associated with the risk of mortality from chronic kidney disease.
Abstract
OBJECTIVES: This study investigated conventional cardiovascular and lifestyle risk factors affecting mortality from chronic kidney disease as the underlying cause in the general Japanese population.METHODS: We conducted an 18.8-year follow-up study of 44,792 men and 61,522 women aged 40-79 from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk between 1986 and 1990. Cox proportional hazard models were used to analyze the association between risk factors and mortality from chronic kidney disease.RESULTS: During the follow-up period, 373 participants (185 men and 188 women) died from chronic kidney disease. A body mass index of ≥27.0 kg/m2 (hazard ratio [HR], 2.00; 95% confidence interval [CI], 1.19 to 3.36 for men and HR, 1.91; 95% CI, 1.19 to 3.07 for women, compared with 23.0-24.9 kg/m2), a history of hypertension (HR, 2.32; 95% CI, 1.67 to 3.22 for men and HR, 2.01; 95% CI, 1.44 to 2.81 for women) and a history of diabetes mellitus (HR, 5.21; 95% CI, 3.68 to 7.37 for men and HR, 7.10; 95% CI, 4.93 to 10.24 for women) were associated with an increased risk of mortality from chronic kidney disease in both genders. In men, smoking was also associated with an increased risk (HR, 1.91; 95% CI, 1.25 to 2.90), while current drinking (HR, 0.58; 95% CI, 0.34 to 0.98 for <23 g/day; HR, 0.48; 95% CI, 0.29 to 0.80 for 23-45 g/day and HR, 0.53; 95% CI, 0.32 to 0.86 for ≥46 g/day) and exercising ≥5 hr/wk (HR, 0.42; 95% CI, 0.18 to 0.96) were associated with a lower risk. Similar but non-significant associations for smoking and drinking were observed in women.CONCLUSIONS: In addition to a history of hypertension and a history of diabetes mellitus, body mass index, smoking status, drinking status, and exercise habits were associated with the risk of mortality from chronic kidney disease.
참고문헌 (40)
- Nagai K, "Estimating the prevalence of definitive chronic kidney disease in the Japanese general population", Clin Exp Nephrol, 25, pp.885~892 (2021)[DOI]
- Astor BC, "Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts", Kidney Int, 79, pp.1331~1140 (2011)[DOI]
- "2022 Annual data report" (2022)[URL]
- Go AS, "Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization", N Engl J Med, 351, pp.1296~1305 (2004)[DOI]
- Keith DS, "Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization", Arch Intern Med, 164, pp.659~663 (2004)[DOI]
- Diamond JR, "Focal and segmental glomerulosclerosis : analogies to atherosclerosis", Kidney Int, 33, pp.917~924 (1988)[DOI]
- Haller H, "Calcium antagonists and cellular mechanisms of glomerulosclerosis and atherosclerosis", Am J Kidney Dis, 21(6 Suppl 3), pp.26~31 (1993)
- Khan SS, "Association of body mass index with lifetime risk of cardiovascular disease and compression of morbidity", JAMA Cardiol, 3, pp.280~287 (2018)[DOI]
- Taghizadeh N, "Lifetime smoking history and cause-specific mortality in a cohort study with 43 years of follow-up", PLoS One, 11, pp.e0153310~ (2016)[DOI]
- Ronksley PE, "Association of alcohol consumption with selected cardiovascular disease outcomes : a systematic review and meta-analysis", BMJ, 342, pp.d671~ (2011)[DOI]
- Lavie CJ, "Sedentary behavior, exercise, and cardiovascular health", Circ Res, 124, pp.799~815 (2019)[DOI]
- Gelber RP, "Association between body mass index and CKD in apparently healthy men", Am J Kidney Dis, 46, pp.871~880 (2005)[DOI]
- Elsayed EF, "Waist-to-hip ratio, body mass index, and subsequent kidney disease and death", Am J Kidney Dis, 52, pp.29~38 (2008)[DOI]
- Yamagata K, "Risk factors for chronic kidney disease in a community-based population : a 10-year follow-up study", Kidney Int, 71, pp.159~166 (2007)[DOI]
- Shankar A, "The association among smoking, heavy drinking, and chronic kidney disease", Am J Epidemiol, 164, pp.263~271 (2006)[DOI]
- White SL, "Alcohol consumption and 5-year onset of chronic kidney disease : the AusDiab study", Nephrol Dial Transplant, 24, pp.2464~2472 (2009)[DOI]
- Kimura Y, "Alcohol consumption and incidence of proteinuria : a retrospective cohort study", Clin Exp Nephrol, 22, pp.1133~1142 (2018)[DOI]
- Koning SH, "Alcohol consumption is inversely associated with the risk of developing chronic kidney disease", Kidney Int, 87, pp.1009~1016 (2015)[DOI]
- Wakasugi M, "A combination of healthy lifestyle factors is associated with a decreased incidence of chronic kidney disease : a population-based cohort study", Hypertens Res, 36, pp.328~333 (2013)[DOI]
- Tamakoshi A, "Cohort profile of the Japan Collaborative Cohort Study at final follow-up", J Epidemiol, 23, pp.227~232 (2013)[DOI]
- GBD 2013 Mortality, "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013 : a systematic analysis for the Global Burden of Disease Study 2013", Lancet, 385, pp.117~171 (2015)[DOI]
- Chang Y, "Metabolically healthy obesity and development of chronic kidney disease : a cohort study", Ann Intern Med, 164, pp.305~312 (2016)[DOI]
- Vupputuri S, "Lifestyle risk factors and chronic kidney disease", Ann Epidemiol, 13, pp.712~720 (2003)[DOI]
- Stengel B, "Lifestyle factors, obesity and the risk of chronic kidney disease", Epidemiology, 14, pp.479~487 (2003)[DOI]
- Knight EL, "Moderate alcohol intake and renal function decline in women : a prospective study", Nephrol Dial Transplant, 18, pp.1549~1554 (2003)[DOI]
- Brien SE, "Effect of alcohol consumption on biological markers associated with risk of coronary heart disease : systematic review and meta-analysis of interventional studies", BMJ, 342, pp.d636~ (2011)[DOI]
- Burchfiel CM, "Cardiovascular risk factors and hyalinization of renal arterioles at autopsy. The Honolulu Heart Program", Arterioscler Thromb Vasc Biol, 17, pp.760~768 (1997)[DOI]
- Hong FF, "Roles of eNOS in atherosclerosis treatment", Inflamm Res, 68, pp.429~441 (2019)[DOI]
- Obermayr RP, "Predictors of new-onset decline in kidney function in a general middle-european population", Nephrol Dial Transplant, 23, pp.1265~1273 (2008)[DOI]
- Inaguma D, "Risk factors for CKD progression in Japanese patients : findings from the Chronic Kidney Disease Japan Cohort(CKD-JAC)study", Clin Exp Nephrol, 21, pp.446~456 (2017)[DOI]
- Haroun MK, "Risk factors for chronic kidney disease : a prospective study of 23, 534 men and women in Washington County, Maryland", J Am Soc Nephrol, 14, pp.2934~2941 (2003)[DOI]
- Hallan SI, "Smoking is a risk factor in the progression to kidney failure", Kidney Int, 80, pp.516~523 (2011)[DOI]
- Pinto-Sietsma SJ, "Smoking is related to albuminuria and abnormal renal function in nondiabetic persons", Ann Intern Med, 133, pp.585~591 (2000)[DOI]
- Hisamatsu T, "Smoking, smoking cessation, and measures of subclinical atherosclerosis in multiple vascular beds in Japanese men", J Am Heart Assoc, 5, pp.e003738~ (2016)[DOI]
- Zhou XJ, "The aging kidney", Kidney Int, 74, pp.710~720 (2008)[DOI]
- Umesawa M, "Validity of a risk prediction equation for CKD after 10 years of follow-up in a Japanese poulation : the Ibaraki Prefectural Health Study", Am J Kidney Dis, 71, pp.842~850 (2018)[DOI]
- Hanratty R, "Relationship between blood pressure and incident chronic kidney disease in hypertensive patients", Clin J Am Soc Nephrol, 6, pp.2605~2611 (2011)[DOI]
- Reynolds K, "A population-based, prospective study of blood pressure and risk for end-stage renal disease in China", J Am Soc Nephrol, 18, pp.1928~1935 (2007)[DOI]
- Tozawa M, "Blood pressure predicts risk of developing end-stage renal disease in men and women", Hypertension, 41, pp.1341~1345 (2003)[DOI]
- Hippisley-Cox J, "Predicting the risk of chronic kidney disease in men and women in England and Wales : prospective derivation and external validation of the QKidney Scores", BMC Fam Pract, 11, pp.49~ (2010)[DOI]