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The effectiveness of protein supplementation combined with resistance exercise programs among community-dwelling older adults with sarcopenia: a systematic review and meta-analysis

Whaikid Phatcharaphon|Piaseu Noppawan
한국역학회 (Korean Society of Epidemiology)|2024.01|Epidemiology and Health|제46권 |pp. 30-30|DOI 10.4178/epih.e2024030

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키워드

CommunityMeta-analysisSarcopeniaResistance exerciseProtein supplementation

초록

OBJECTIVES The combination of protein supplementation and resistance exercise shows promise for improving and maintaining muscle mass, strength, and performance in older adults with sarcopenia. This systematic review aimed to evaluate the effects of this combination on muscle mass, muscle strength, and physical performance in community-dwelling older adults with sarcopenia. METHODS We conducted a comprehensive search of 4 electronic databases: PubMed, Scopus, Embase, and the MEDLINE Library. The search covered literature from January 2013 to January 2023 and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Two independent reviewers assessed the methodological quality of each study using the standard critical appraisal tool from the Joanna Briggs Institute (JBI). Meta-analysis was performed with the JBI Sumari program. RESULTS The review included 7 randomized controlled trials and 1 quasi-experimental study, encompassing a total of 854 participants aged 60 years and above. The study durations ranged from 10 weeks to 24 weeks. An analysis of standardized mean differences (SMDs) showed that protein supplementation combined with resistance exercise significantly increased muscle mass (SMD, 0.95; 95% confidence interval [CI], 0.13 to 1.78; p<0.05) and muscle strength (SMD, 0.32; 95% CI, 0.08 to 0.56; p<0.05). CONCLUSIONS Although the limited number of randomized controlled trials restricts the robustness of our conclusions, the evidence suggests that protein supplementation combined with resistance exercise is effective in enhancing muscle mass and strength in community-dwelling older adults with sarcopenia.

Abstract

OBJECTIVES The combination of protein supplementation and resistance exercise shows promise for improving and maintaining muscle mass, strength, and performance in older adults with sarcopenia. This systematic review aimed to evaluate the effects of this combination on muscle mass, muscle strength, and physical performance in community-dwelling older adults with sarcopenia. METHODS We conducted a comprehensive search of 4 electronic databases: PubMed, Scopus, Embase, and the MEDLINE Library. The search covered literature from January 2013 to January 2023 and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Two independent reviewers assessed the methodological quality of each study using the standard critical appraisal tool from the Joanna Briggs Institute (JBI). Meta-analysis was performed with the JBI Sumari program. RESULTS The review included 7 randomized controlled trials and 1 quasi-experimental study, encompassing a total of 854 participants aged 60 years and above. The study durations ranged from 10 weeks to 24 weeks. An analysis of standardized mean differences (SMDs) showed that protein supplementation combined with resistance exercise significantly increased muscle mass (SMD, 0.95; 95% confidence interval [CI], 0.13 to 1.78; p<0.05) and muscle strength (SMD, 0.32; 95% CI, 0.08 to 0.56; p<0.05). CONCLUSIONS Although the limited number of randomized controlled trials restricts the robustness of our conclusions, the evidence suggests that protein supplementation combined with resistance exercise is effective in enhancing muscle mass and strength in community-dwelling older adults with sarcopenia.

참고문헌 (56)

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Improved Muscle Mass and Function With Protein Supplementation in Older Adults With Sarcopenia: A Meta-AnalysisChoi Seo Won, Koh Seong-Eun, Ko Nayeon, Kwon Hyo Eun, Yuk Doyoung대한재활의학회 · Annals of Rehabilitation Medicine2023 · 제47권 제5호근감소증을 가진 고령자의 근육량, 근력 및 신체 수행력에 저항 운동의 효과: 체계적 고찰과 메타분석강현주, 김경민한국운동생리학회 · 운동과학2020 · 제29권 제2호Unraveling Anabolic Resistance in Sarcopenia: A Narrative Synthesis of Age-Related Impairments in Muscle Protein Synthesis강현주대한운동학회 · 아시아 운동학 학술지2025 · 제27권 제3호Effects of Resistance Training and/or Protein Supplementation on Usual Gait Speed in Postmenopausal Women: A Systematic Review and Meta-Analysis박석, 박재호, Junghwan oh한국운동생리학회 · 운동과학2022 · 제31권 제1호The Effects of Protein and Supplements on Sarcopenia in Human Clinical Studies: How Older Adults Should Consume Protein and Supplements장영진한국미생물·생명공학회 · Journal of Microbiology and Biotechnology2023 · 제33권 제2호Effects of Resistance Exercise on Older Individuals with Sarcopenia: Sex Differences in Humans박석, 노기웅한국운동생리학회 · 운동과학2023 · 제32권 제3호

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