Association Between Eustachian Tube Dysfunction Questionnaire-7 Scores and Eustachian Tube Function Test Results in Symptomatic Patients With a Normal Drum
3
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background and Objectives: We investigated the clinical validity of and correlation between the Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7) scores and the eustachian tube function test (ETFT) results in patients with a normal drum. Subjects and Methods: The study included 49 patients (93 ears) with unilateral or bilateral ear fullness over >3 months. All patients were administered the ETDQ-7 survey and underwent the ETFT on the same day. The receiver operating characteristic (ROC) curve and the association between the results were statistically analyzed. Results: ETDQ-7 scores were not significantly correlated with the ETFT results or with middle ear pressure. ETDQ-7 scores in patients with eustachian tube dysfunction (ETD) were significantly higher than those in patients with normal ETFT results (<i>p</i>=0.039) when ETD was defined as a pressure change <10 daPa on the ETFT. The area under the ROC curve was 0.631, with a sensitivity of 37.0% and specificity of 89.4%. Conclusions: The ETDQ-7 has limited clinical significance in patients with ETD but a normal drum. Therefore, concomitant objective tests should be performed to diagnose patients with ETD.
Abstract
Background and Objectives: We investigated the clinical validity of and correlation between the Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7) scores and the eustachian tube function test (ETFT) results in patients with a normal drum. Subjects and Methods: The study included 49 patients (93 ears) with unilateral or bilateral ear fullness over >3 months. All patients were administered the ETDQ-7 survey and underwent the ETFT on the same day. The receiver operating characteristic (ROC) curve and the association between the results were statistically analyzed. Results: ETDQ-7 scores were not significantly correlated with the ETFT results or with middle ear pressure. ETDQ-7 scores in patients with eustachian tube dysfunction (ETD) were significantly higher than those in patients with normal ETFT results (<i>p</i>=0.039) when ETD was defined as a pressure change <10 daPa on the ETFT. The area under the ROC curve was 0.631, with a sensitivity of 37.0% and specificity of 89.4%. Conclusions: The ETDQ-7 has limited clinical significance in patients with ETD but a normal drum. Therefore, concomitant objective tests should be performed to diagnose patients with ETD.
참고문헌 (33)
- Bluestone CD, "Anatomy and physiology of eustachian tube and middle ear related to otitis media", J Allergy Clin Immunol, 81(5 Pt 2), pp.997~1003 (1988)
- Ars B, "Eustachian tube function", Otolaryngol Clin North Am, 49, pp.1121~1133 (2016)
- Sadé J, "Middle ear and auditory tube : middle ear clearance, gas exchange, and pressure regulation", Otolaryngol Head Neck Surg, 116, pp.499~524 (1997)
- Schilder AG, "Eustachian tube dysfunction : consensus statement on definition, types, clinical presentation and diagnosis", Clin Otolaryngol, 40, pp.407~411 (2015)
- Smith ME, "Imaging of the eustachian tube and its function : a systematic review", Neuroradiology, 58, pp.543~556 (2016)
- Alper CM, "Panel 2 : anatomy(eustachian tube, middle ear, and mastoid—anatomy, physiology, pathophysiology, and pathogenesis)", Otolaryngol Head Neck Surg, 156(4_suppl), pp.S22~S40 (2017)
- Seibert JW, "Eustachian tube function and the middle ear", Otolaryngol Clin North Am, 39, pp.1221~1235 (2006)
- Sente M, "Importance of the eustachian tube in middle ear function", Med Pregl, 48, pp.405~406 (1995)
- McCoul ED, "Validating the clinical assessment of eustachian tube dysfunction : the eustachian tube dysfunction questionnaire(ETDQ-7)", Laryngoscope, 122, pp.1137~1141 (2012)
- Hamrang-Yousefi S, "Eustachian tube dysfunction" (2022), StatPearls Publishing
- Meyer TA, "A randomized controlled trial of balloon dilation as a treatment for persistent eustachian tube dysfunction with 1-year follow-up", Otol Neurotol, 39, pp.894~902 (2018)
- Bluestone CD, "Current clinical methods, indications and interpretation of eustachian tube function tests", Ann Otol Rhinol Laryngol, 90(6 Pt 1), pp.552~562 (1981)
- Olander H, "Critical distance between the cartilaginous eustachian tube and the internal carotid artery", Eur Arch Otorhinolaryngol, 274, pp.73~77 (2017)
- Schröder S, "Evaluation of tubomanometry as a routine diagnostic tool for chronic obstructive eustachian tube dysfunction", Clin Otolaryngol, 40, pp.691~697 (2015)
- Herrera M, "Clinical assessment of eustachian tube dysfunction through the eustachian tube dysfunction questionnaire(ETDQ-7)and tubomanometry", Acta Otorrinolaringol Esp(Engl Ed), 70, pp.265~271 (2019)
- Alper CM, "Diagnostic accuracy of tubomanometry R value in detecting the eustachian tube pressure equalizing function", Eur Arch Otorhinolaryngol, 274, pp.1865~1872 (2017)
- Martino E, "Function tests for the Eustachian tube. Current knowledge", HNO, 52, pp.1029~1039 (2004)
- Teixeira MS, "Accuracy of the ETDQ-7 for identifying persons with eustachian tube dysfunction", Otolaryngol Head Neck Surg, 158, pp.83~89 (2018)
- McBride TP, "Evaluation of noninvasive eustachian tube function tests in normal adults", Laryngoscope, 98(6 Pt 1), pp.655~658 (1988)
- Smith ME, "Eustachian tube dysfunction : a diagnostic accuracy study and proposed diagnostic pathway", PLoS One, 13, pp.e0206946~ (2018)
- Smith ME, "Tests of eustachian tube function : a review", Clin Otolaryngol, 40, pp.300~311 (2015)
- Özgür E, "Turkish validity and reliability of eustachian tube dysfunction questionnaire-7", Braz J Otorhinolaryngol, 84, pp.435~440 (2018)
- Hansen LJ, "Validating the 7-item Eustachian tube dysfunction questionnaire in Danish", Dan Med J, 67, pp.A11190617~ (2020)
- Menezes AS, "Translation and validation of the"7-Item Eustachian Tube Dysfunction Questionnaire"to European Portuguese(PT)", Acta Med Port, 33, pp.191~197 (2020)
- Ungar OJ, "The Hebrew version of the eustachian tube dysfunction questionnaire-7", Hear Balance Commun, 16, pp.114~119 (2018)
- Chen X, "Local versus general anesthesia for balloon dilation of the Eustachian tube : a single-center retrospective study in a Chinese population", Ear Nose Throat J (2020)[DOI]
- Cutler JL, "Long-term outcomes of balloon dilation for persistent eustachian tube dysfunction", Otol Neurotol, 40, pp.1322~1325 (2019)
- Parsel SM, "Interpretation of normal and abnormal tympanogram findings in eustachian tube dysfunction", Otolaryngol Head Neck Surg, 164, pp.1272~1279 (2021)
- Lin WL, "Evaluation of thirty patients with eustachian tube dysfunction in Taiwan by questionnaire survey", J Formos Med Assoc, 119, pp.621~626 (2020)
- Schröder S, "A novel diagnostic tool for chronic obstructive eustachian tube dysfunction—the eustachian tube score", Laryngoscope, 125, pp.703~708 (2015)
- Swarts JD, "Panel 2 : eustachian tube, middle ear, and mastoid--anatomy, physiology, pathophysiology, and pathogenesis", Otolaryngol Head Neck Surg, 148(4 Suppl), pp.E26~E36 (2013)
- Alper CM, "Magnetic resonance imaging of the development of otitis media with effusion caused by functional obstruction of the eustachian tube", Ann Otol Rhinol Laryngol, 106, pp.422~431 (1997)
- Doyle WJ, "Middle ear gas exchange in rhesus monkeys", Ann Otol Rhinol Laryngol, 103(8 Pt 1), pp.636~645 (1994)
