Two-Stage Reimplantation in Infected Total Knee Arthroplasty
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Two-stage reimplantation is considered the gold standard for the management of periprosthetic joint infection. The first stage involves the removal of the prosthesis, followed by extensive debridement of all nonviable tissues, synovectomy, irrigation, and reaming of the medullary canals. Once the joint has been prepared, antibiotic-impregnated cement beads and/or spacer are inserted. Antibiotic-impregnated spacers are now more commonly used, and an increasing number of orthopaedic surgeons are using articulating spacers if indicated. Antibiotics are then prescribed to the patient based on the sensitivities of the infecting organism. The duration of systemic antibiotic use is decreasing, and short courses of antibiotic therapy have been shown to be as efficacious as prolonged therapy between the first and second stages. The second stage of the procedure involves removal of the antibiotic-impregnated cement beads and/or spacer, repeat irrigation and debridement, and final reconstruction with revision components. While two-stage reimplantation was considered the gold standard in many parts of the world, recent studies have demonstrated that it is associated with a considerable failure rate. This may be due to the lack of accurate diagnostic tools for infection eradication, and future investigation of risk factors for failure of the two-stage reimplantation should be conducted.
Abstract
Two-stage reimplantation is considered the gold standard for the management of periprosthetic joint infection. The first stage involves the removal of the prosthesis, followed by extensive debridement of all nonviable tissues, synovectomy, irrigation, and reaming of the medullary canals. Once the joint has been prepared, antibiotic-impregnated cement beads and/or spacer are inserted. Antibiotic-impregnated spacers are now more commonly used, and an increasing number of orthopaedic surgeons are using articulating spacers if indicated. Antibiotics are then prescribed to the patient based on the sensitivities of the infecting organism. The duration of systemic antibiotic use is decreasing, and short courses of antibiotic therapy have been shown to be as efficacious as prolonged therapy between the first and second stages. The second stage of the procedure involves removal of the antibiotic-impregnated cement beads and/or spacer, repeat irrigation and debridement, and final reconstruction with revision components. While two-stage reimplantation was considered the gold standard in many parts of the world, recent studies have demonstrated that it is associated with a considerable failure rate. This may be due to the lack of accurate diagnostic tools for infection eradication, and future investigation of risk factors for failure of the two-stage reimplantation should be conducted.
참고문헌 (47)
- Parvizi J, "Management of periprosthetic joint infection: the current knowledge: AAOS exhibit selection", J Bone Joint Surg Am, 94, pp.e104~ (2012)[DOI]
- Parvizi J, "AAOS Clinical Practice Guideline: diagnosis and treatment of periprosthetic joint infections of the hip and knee", J Am Acad Orthop Surg, 18, pp.771~772 (2010)[DOI]
- Parvizi J, "New definition for periprosthetic joint infection: from the Workgroup of the Musculoskeletal Infection Society", Clin Orthop Relat Res, 469, pp.2992~2994 (2011)[DOI]
- Kunutsor SK, "Re-infection outcomes following one- and two-stage surgical revision of infected knee prosthesis: a systematic review and meta-analysis", PLoS One, 11, pp.e0151537~ (2016)[DOI]
- Gehrke T, "The management of an infected total knee arthroplasty", Bone Joint J, 97(10 Suppl A), pp.20~29 (2015)[DOI]
- Ghanem E, "Staged revision for knee arthroplasty infection: what is the role of serologic tests before reimplantation?", Clin Orthop Relat Res, 467, pp.1699~1705 (2009)[DOI]
- Goksan SB, "One-stage reimplantation for infected total knee arthroplasty", J Bone Joint Surg Br, 74, pp.78~82 (1992)
- Kuzyk PR, "Two-stage revision arthroplasty for management of chronic periprosthetic hip and knee infection: techniques, controversies, and outcomes", J Am Acad Orthop Surg, 22, pp.153~164 (2014)[DOI]
- Silva M, "Results of direct exchange or debridement of the infected total knee arthroplasty", Clin Orthop Relat Res, (404), pp.125~131 (2002)
- Insall JN, "Two-stage reimplantation for the salvage of infected total knee arthroplasty", J Bone Joint Surg Am, 65, pp.1087~1098 (1983)[DOI]
- Joseph TN, "Use of antibioticimpregnated cement in total joint arthroplasty", J Am Acad Orthop Surg, 11, pp.38~47 (2003)[DOI]
- Luu A, "Two-stage arthroplasty for prosthetic joint infection: a systematic review of acute kidney injury, systemic toxicity and infection control", J Arthroplasty, 28, pp.1490~1498 (2013)[DOI]
- Fink B, "Sufficient release of antibiotic by a spacer 6 weeks after implantation in two-stage revision of infected hip prostheses", Clin Orthop Relat Res, 469, pp.3141~3147 (2011)[DOI]
- Qiu XS, "Application of an articulating spacer in two-stage revision for severe infection after total knee arthroplasty", Orthop Surg, 2, pp.299~304 (2010)[DOI]
- Hsieh PH, "Two-stage revision hip arthroplasty for infection: comparison between the interim use of antibiotic-loaded cement beads and a spacer prosthesis", J Bone Joint Surg Am, 86, pp.1989~1997 (2004)[DOI]
- Hofmann AA, "Tenyear experience using an articulating antibiotic cement hip spacer for the treatment of chronically infected total hip", J Arthroplasty, 20, pp.874~879 (2005)[DOI]
- Guild GN 3rd, "Articulating vs. static antibiotic impregnated spacers in revision total knee arthroplasty for sepsis: a systematic review", J Arthroplasty, 29, pp.558~563 (2014)[DOI]
- Parvizi J, "Proceedings of the international consensus on periprosthetic joint infection", Bone Joint J, 95, pp.1450~1452 (2013)[DOI]
- Pivec R, "Systematic review comparing static and articulating spacers used for revision of infected total knee arthroplasty", J Arthroplasty, 29, pp.553~557 (2014)[DOI]
- Voleti PB, "Use of static or articulating spacers for infection following total knee arthroplasty: a systematic literature review", J Bone Joint Surg Am, 95, pp.1594~1599 (2013)[DOI]
- Hsieh PH, "Two-stage revision of infected hip arthroplasty using an antibiotic-loaded spacer: retrospective comparison between short-term and prolonged antibiotic therapy", J Antimicrob Chemother, 64, pp.392~397 (2009)[DOI]
- Masri BA, "Long-term elution of antibiotics from bone-cement: an in vivo study using the prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) system", J Arthroplasty, 13, pp.331~338 (1998)[DOI]
- Hart WJ, "Two-stage revision of infected total knee replacements using articulating cement spacers and shortterm antibiotic therapy", J Bone Joint Surg Br, 88, pp.1011~1015 (2006)[DOI]
- Whittaker JP, "Is prolonged systemic antibiotic treatment essential in two-stage revision hip replacement for chronic Gram-positive infection?", J Bone Joint Surg Br, 91, pp.44~51 (2009)[DOI]
- Lichstein P, "One-stage versus two-stage exchange", J Orthop Res, 32(Suppl 1), pp.S141~S146 (2014)[DOI]
- Zywiel MG, "Prophylactic oral antibiotics reduce reinfection rates following two-stage revision total knee arthroplasty", Int Orthop, 35, pp.37~42 (2011)[DOI]
- Zmistowski B, "Diagnosis of periprosthetic joint infection", J Arthroplasty, 29(2 Suppl), pp.77~83 (2014)[DOI]
- Frangiamore SJ, "Synovial cytokines and the MSIS criteria are not useful for determining infection resolution after periprosthetic joint infection explantation", Clin Orthop Relat Res, 474, pp.1630~1639 (2016)[DOI]
- Vielgut I, "Two-stage revision of prosthetic hip joint infections using antibioticloaded cement spacers: when is the best time to perform the second stage", Int Orthop, 39, pp.1731~1736 (2015)[DOI]
- Hoell S, "Two-stage revision arthroplasty for periprosthetic joint infections: what is the value of cultures and white cell count in synovial fluid and CRP in serum before second stage reimplantation?", Arch Orthop Trauma Surg, 136, pp.447~452 (2016)[DOI]
- Kusuma SK, "What is the role of serological testing between stages of twostage reconstruction of the infected prosthetic knee?", Clin Orthop Relat Res, 469, pp.1002~1008 (2011)[DOI]
- Shukla SK, "Perioperative testing for persistent sepsis following resection arthroplasty of the hip for periprosthetic infection", J Arthroplasty, 25(6 Suppl), pp.87~91 (2010)
- Virolainen P, "The reliability of diagnosis of infection during revision arthroplasties", Scand J Surg, 91, pp.178~181 (2002)[DOI]
- Deirmengian C, "Synovial fluid biomarkers for periprosthetic infection", Clin Orthop Relat Res, 468, pp.2017~2023 (2010)[DOI]
- Deirmengian C, "Diagnosing periprosthetic joint infection: has the era of the biomarker arrived?", Clin Orthop Relat Res, 472, pp.3254~3262 (2014)[DOI]
- Diaz-Ledezma C, "Success after treatment of periprosthetic joint infection: a Delphi-based international multidisciplinary consensus", Clin Orthop Relat Res, 471, pp.2374~2382 (2013)[DOI]
- Nelson CL, "Sonication of antibiotic spacers predicts failure during twostage revision for prosthetic knee and hip infections", Clin Orthop Relat Res, 472, pp.2208~2214 (2014)[DOI]
- Atkins D, "Grading quality of evidence and strength of recommendations", BMJ, 328, pp.1490~ (2004)[DOI]
- Wyatt MC, "The alpha-defensin immunoassay and leukocyte esterase colorimetric strip test for the diagnosis of periprosthetic infection: a systematic review and metaanalysis", J Bone Joint Surg Am, 98, pp.992~1000 (2016)[DOI]
- Mont MA, "Evaluation of preoperative cultures before second-stage reimplantation of a total knee prosthesis complicated by infection: a comparison-group study", J Bone Joint Surg Am, 82, pp.1552~1557 (2000)[DOI]
- Williams JL, "The value of hip aspiration versus tissue biopsy in diagnosing infection before exchange hip arthroplasty surgery", J Arthroplasty, 19, pp.582~586 (2004)[DOI]
- Della Valle CJ, "Analysis of frozen sections of intraoperative specimens obtained at the time of reoperation after hip or knee resection arthroplasty for the treatment of infection", J Bone Joint Surg Am, 81, pp.684~689 (1999)[DOI]
- Huang MJ, "Use of positron emission tomography to detect infection around antibiotic-loaded cement spacers in patients with high C-reactive protein levels", Orthopedics, 34, pp.e605~e609 (2011)
- Scher DM, "The predictive value of indium-111 leukocyte scans in the diagnosis of infected total hip, knee, or resection arthroplasties", J Arthroplasty, 15, pp.295~300 (2000)[DOI]
- Della Valle C, "American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis of periprosthetic joint infections of the hip and knee", J Bone Joint Surg Am, 93, pp.1355~1357 (2011)[DOI]
- Mortazavi SM, "Two-stage exchange arthroplasty for infected total knee arthroplasty: predictors of failure", Clin Orthop Relat Res, 469, pp.3049~3054 (2011)[DOI]
- Masters JP, "A systematic review of the evidence for single stage and two stage revision of infected knee replacement", BMC Musculoskelet Disord, 14, pp.222~ (2013)[DOI]