일 광역시 당뇨병 환자의 주관적 기억력 장애 관련 요인
Factors Associated with Subjective Memory Impairment in Patients with Diabetes Mellitus in a Metropolitan City
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Objective: The purpose of this study was to identify factors associated with subjective memory impairment in patients with diabetes mellitus in a metropolitan city. Methods: The subjects of this study were 351 patients with diabetes mellitus aged 50 and over from five districts of Gwangju who participated in the 2018 Community Health Survey. We analyzed general characteristics, health-related behaviors and health related conditions and subjective experience of memory impairment. To find factors associated with subjective memory impairment, the chi-square test and multiple logistic regression analysis were used. Results: Of all subjects, 31.3% was reported subjective experience of memory impairment. The odds ratios (ORs; 95% confidence interval (CI)) for subjective memory impairment according to age were statistically significant at 1.9 (0.9-4.3) in patients in 60s and 2.2 (1.1-4.7) in patients in beyond 70s compared to those in 50s. The OR (95% CI) of ex-smoker compared to the non-smoker was 0.3 (0.8-0.9). The OR (95% CI) of depressive symptom compared to no depressive symptoms was 4.9 (95% CI: 1.8-13.7). Conclusion: In this study, subjective memory impairment in patients with diabets mellitus was associated with age, smoking, and depressive symptoms. Based on the results of this study, subjective memory impairment should be detected early through periodic cognitive function evaluation for elderly patients with diabetes mellitus, and a program for healthy cognitive function should be included in diabetes management program.
Abstract
Objective: The purpose of this study was to identify factors associated with subjective memory impairment in patients with diabetes mellitus in a metropolitan city. Methods: The subjects of this study were 351 patients with diabetes mellitus aged 50 and over from five districts of Gwangju who participated in the 2018 Community Health Survey. We analyzed general characteristics, health-related behaviors and health related conditions and subjective experience of memory impairment. To find factors associated with subjective memory impairment, the chi-square test and multiple logistic regression analysis were used. Results: Of all subjects, 31.3% was reported subjective experience of memory impairment. The odds ratios (ORs; 95% confidence interval (CI)) for subjective memory impairment according to age were statistically significant at 1.9 (0.9-4.3) in patients in 60s and 2.2 (1.1-4.7) in patients in beyond 70s compared to those in 50s. The OR (95% CI) of ex-smoker compared to the non-smoker was 0.3 (0.8-0.9). The OR (95% CI) of depressive symptom compared to no depressive symptoms was 4.9 (95% CI: 1.8-13.7). Conclusion: In this study, subjective memory impairment in patients with diabets mellitus was associated with age, smoking, and depressive symptoms. Based on the results of this study, subjective memory impairment should be detected early through periodic cognitive function evaluation for elderly patients with diabetes mellitus, and a program for healthy cognitive function should be included in diabetes management program.
참고문헌 (32)
- Kahn SE, "Pathophysiology and treatment of type 2diabetes. perspectives on the past, present and future", Lancet, 383(9922), pp.1068~1083 (2014)
- "Korea Health Statistics 2020: Korea National Health and Nutrition Examination Survey (KNHANES VIII-2)"[URL]
- Yuan XY, "Mild cognitive impairment in type 2 diabetes mellitus and related risk factors: a review", Rev Neurosci, 28(7), pp.715~723 (2017)
- 김용숙, "지역사회에 거주하는 당뇨병 노인과 일반 노인의 인지기능 비교", 지역사회간호학회지, 22(4), pp.377~388 (2011), 한국지역사회간호학회
- Stratton IM, "Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study", BMJ, 321(7258), pp.405~412 (2000)
- He X, "Diabetes self-management education reduces risk of all-cause mortality in type 2 diabetes patients: a systematic review and meta-analysis", Endocrine, 55(3), pp.712~731 (2017)
- 이숙희, "자기효능증진프로그램이 당뇨환자의 자기효능, 혈당대사 및 자기간호실천행위에 미치는 효과", 재활간호학회지, 8(1), pp.59~67 (2005), 한국재활간호학회
- 권영은, "지역사회에 거주하는 노인 당뇨환자의 자가 관리 영향요인", 한국생활환경학회지, 18(1), pp.92~100 (2011), 한국생활환경학회
- Sinclair AJ, "Cognitive dysfunction in older subjects with diabetes mellitus: impact on diabetes self-management and use of care services. All Wales Research into Elderly (AWARE) Study", Diaabetes Res Clin Pract, 50(3), pp.203~212 (2000)
- Novak V, "Diabetes-related cognitive decline, a global health issue and new treatment approaches", Int J Priv Health Inf manag, 5(2), pp.58~70 (2017)
- Youn JC, "Association between subjective memory complaint and objective cognitive decline in the elderly", Kor J Psychopathol, 12(1, 2), pp.17~23 (2003)
- Montejo P, "Memory complaints in the elderly: Quality of life and daily living activities. A population based study", Arch Gerontol Geriatr, 54(2), pp.298~304 (2012)
- 이성애, "노인들의 주관적 기억문제 호소와 객관적인 인지 기능의 연관성 -Normal, Mild Cognitive Impairment, Dementia 군의 비교를 중심으로", Korean Journal of Clinical Psychology, 30(1), pp.247~261 (2011), 한국임상심리학회[DOI]
- Treves TA, "Incidence of dementia in patients with subjective memory complaints", Int Psychogeriatr, 17(2), pp.265~273 (2005)
- Cukierman T, "Cognitive decline and dementia in diabetes —systematic overview of prospective observational studies", Diabetologia, 48(12), pp.2460~2469 (2005)
- Allen KV, "The relationship between type 2 diabetes and cognitive dysfunction: longitudinal studies and their methodological limitations", Eur J Pharmacol, 490(1-3), pp.169~175 (2004)
- Lee SH, "Connections between diabetes and cognitive dysfunction", J Korean Diabetes, 20(1), pp.67~73 (2019)
- 정미하, "인슐린 비의존성 당뇨병 환자의 인지기능", 재활간호학회지, 8(1), pp.38~49 (2005), 한국재활간호학회
- Ebady SA, "Investigation on the relationship between diabetes mellitus type 2 and cognitive impairment", Diabetes Res Clinic Pract, 82(3), pp.305~309 (2008)
- Guerrero-Berroa E, "Depressive symptoms are associated with cognitive function in the elderly with type 2diabetes", J Alzheimers Dis, 65(2), pp.683~692 (2018)
- Xia SS, "The factors contributing to cognitive dysfunction in typw 2 diabetic patients", Ann Transl Med, 8(4), pp.104~ (2020)[DOI]
- "2018 Survey Questionnaire Guide for Community Health Survey"[URL]
- 이승현, "우울장애 선별 시 한글판 Patient Health Questionnaire-9의 기준점수(Cut-Off Point)에 대한 타당도 연구", Mood and Emotion, 12(1), pp.32~36 (2014), 대한우울조울병학회
- "2008-2018 Community Health Statististics at a glancee" (2019)[URL]
- Hagger-Johnson G, "Combined impact of smoking and heavy alcohol use on cognitive decline in early old age:Whitehall II prospective cohort study", Rj J Psychiatry, 203(2), pp.120~125 (2013)
- 신희영, "새로운 치매 선별검사를 이용한 도시지역 노인의 치매 유병률과 관련요인", 예방의학회지, 38(3), pp.351~358 (2005), 대한예방의학회
- Anstey KJ, "ASmoking as a risk facfor for dementia and cognitive decline: a meta-analysis of prospective studies", Am J Epidemiol, 166(4), pp.367~378 (2007)
- Blomster JI, "The harms of smoking and benefits of smoking cessation in women compared with men with type 2 diabetes: an observational analysis of the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron modified relaease Controlled Evaluation) trial", BMJ Open, 6, pp.e0009668~ (2016)[DOI]
- Okereke OI, "Type 2 diabetes mellitus and cognitive decline in two large cohorts of community dwelling older adults", J Am Geriatr Soc, 56(6), pp.1028~1036 (2008)
- Rehm J, "The relationship between different dimensions of alcohol use and the burden of disease-an update", Addiction, 112(6), pp.968~1001 (2017)
- Loe H, "Peridontal disease. The sixth complication of diabetes mellitus", Diabetes care, 16(1), pp.329~334 (1993)
- Teixeira FB, "Periodontitis and Alzheimer’s disease: A possible comorbidity between oral chronic inflammatory condition and neuroinflammation", Front Aging Neurosci, 9, pp.327~ (2017)[DOI]