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Effects of age on intestinal phosphate transport and biochemical values of broiler chickens

Jianhui Li|Jianmin Yuan|Zhiqiang Miao|Yuming Guo
아세아·태평양축산학회 (Asian-Australasian Association Of Animal Production Societies)|2017.02|Animal Bioscience|제30권 제2호|pp. 221-228|DOI https://doi.org/10.5713/ajas.16.0540

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참고문헌

키워드

GrowthPhosphorusBroiler ChickensIntestinal TransportBiochemical Values

초록

Objective: The objective of this experiment was to characterize the mRNA expression profile of type IIb sodium-inorganic phosphate cotransporter (NaPi-IIb) and the biochemical values of serum alkaline phosphatase (AKP), calcium, inorganic phosphorus, tibial ash and minerals of broiler chickens with aging. Methods: A total of 56 one-day-old Arbor Acres male broiler chickens were used. Broiler chickens were weighed and samples were collected weekly from day 1. Results: The result showed that before the growth inflection point, ash, calcium, and phosphorus content in the tibia of broiler chickens increased with growth (before 3 weeks of age), although there were no significant differences in chicks at different ages in the later period of the experiment and weight gain rate was relatively slow at this stage (4 to 6 weeks). NaPi-IIb gene expression in the small intestine in the early growth stage was higher than that in the later growth stage. Expression of calbindin and the vitamin D receptor protein in the intestinal mucosa increased with age in the duodenum and jejunum. Serum AKP activity first increased and subsequently decreased after peaking at 1 week of age, but there was no significant difference after 3 weeks of age. Conclusion: These results show that compared with the early growth stage, the weight-gain rate of broiler chickens in the late growth stage gradually decreased with gradual tibia maturation, along with weaker positive transport of phosphorus in the intestine and reinforced re-absorption of phosphorus in the kidney, which might be the reason that phosphorus requirement in the late growth stage was decreased.

Abstract

Objective: The objective of this experiment was to characterize the mRNA expression profile of type IIb sodium-inorganic phosphate cotransporter (NaPi-IIb) and the biochemical values of serum alkaline phosphatase (AKP), calcium, inorganic phosphorus, tibial ash and minerals of broiler chickens with aging. Methods: A total of 56 one-day-old Arbor Acres male broiler chickens were used. Broiler chickens were weighed and samples were collected weekly from day 1. Results: The result showed that before the growth inflection point, ash, calcium, and phosphorus content in the tibia of broiler chickens increased with growth (before 3 weeks of age), although there were no significant differences in chicks at different ages in the later period of the experiment and weight gain rate was relatively slow at this stage (4 to 6 weeks). NaPi-IIb gene expression in the small intestine in the early growth stage was higher than that in the later growth stage. Expression of calbindin and the vitamin D receptor protein in the intestinal mucosa increased with age in the duodenum and jejunum. Serum AKP activity first increased and subsequently decreased after peaking at 1 week of age, but there was no significant difference after 3 weeks of age. Conclusion: These results show that compared with the early growth stage, the weight-gain rate of broiler chickens in the late growth stage gradually decreased with gradual tibia maturation, along with weaker positive transport of phosphorus in the intestine and reinforced re-absorption of phosphorus in the kidney, which might be the reason that phosphorus requirement in the late growth stage was decreased.

참고문헌 (40)

  1. Armbrecht HJ, "Effect of age on calcium and phosphate absorption. Role of 1,25-dihydroxyvitamin D", Miner Electrol Metab, 16, pp.159~166 (1990)
  2. Barreiro FR, "Densitometric and biochemical values of broiler tibias at different ages", Poult Sci, 88, pp.2644~2648 (2009)
  3. Marks J, "Phosphate homeostasis and the renal-gastrointestinal axis", Am J Physiol-Renal, 299, pp.F285~F296 (2010)
  4. Hattenhauer O, "Regulation of small intestinal Na-Pi type IIb cotransporter by dietary phosphate intake", Am J Physiol-Gastr L, 277, pp.G756~G762 (1999)
  5. Murer H, "The sodium phosphate cotransporter family SLC34", Pflügers Arch, 447, pp.763~767 (2004)
  6. Michigami T, "Regulatory mechanism of circulating inorganic phosphate", Clin Calcium, 26, pp.193~198 (2016)
  7. Waldroup PW, "Nonphytate phosphorus requirement and phosphorus excretion of broiler chicks fed diets composed of normal or high available phosphate corn with and without microbial phytase", Poult Sci, 79, pp.1451~1459 (2000)
  8. Dhandu AS, "Broiler nonphytin phosphorus requirement in the finisher and withdrawal phases of a commercial four-phase feeding system", Poult Sci, 82, pp.1257~1265 (2003)
  9. Howe JC, "Dietary protein and phosphorus: effect on calcium and phosphorus metabolism in bone, blood and muscle of the rat", J Nutr, 113, pp.2085~2095 (1983)
  10. Xu H, "Age-dependent regulation of rat intestinal type IIb sodium-phosphate cotransporter by 1,25-(OH)2 vitamin D3", Am J Physiol Cell Physiol, 282, pp.487~493 (2002)
  11. Bar A, "Metabolism and requirements for calcium and phosphorus in the fast-growing chicken as affected by age", Br J Nutr, 89, pp.51~60 (2003)
  12. Li JH, "The effect of dietary nutrient density on growth performance, physiological parameters and small intestinal type IIb sodium phosphate co-transporter expression in broilers", J Anim Sci Biotech, 2, pp.102~110 (2011)
  13. Li JH, "Effect of dietary nutrient density on small intestinal phosphate transport and bone mineralization of broilers during the growing period", Plos one, 11, pp.e0153859~ (2016)
  14. Wang JJ, "Effects of dietary calcium and phosphorus levels on bone growth in broilers from 1 to 3 weeks of age", Chinese J Anim Nutr, 22, pp.1088~1095 (2010)
  15. Han JC, "Effects of 1alpha-hydroxycholecalciferol on growth performance, parameters of tibia and plasma, meat quality, and type IIb sodium phosphate cotransporter gene expression of one- to twenty-one-day-old broilers", Poult Sci, 88, pp.323~329 (2009)
  16. Bradford MM, "Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding", Anal Biochem, 72, pp.248~254 (1976)
  17. Jianhui Li, "The Influence of Dietary Calcium and Phosphorus Imbalance on Intestinal NaPi-IIb and Calbindin mRNA Expression and Tibia Parameters of Broilers", ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 25(4), pp.552~558 (2012), 아세아·태평양축산학회
  18. Nahashon SN, "Growth characteristics of pearl gray guinea fowl as predicted by the richards, gompertz, and logistic models", Poult Sci, 85, pp.359~363 (2006)
  19. Wu ZX, "Comparative analysis of different growth model on the early growth stage of Ross 308 broilers", Gansu Sci and Technol, 26, pp.149~152 (2010)
  20. Chen ZM, "Dynamic growth model and correlative parameters of broilers", pp.2004
  21. Mahmoud KZ, "Breeder age affects small intestine development of broiler chicks with immediate or delayed access to feed", Br. Poult Sci, 53, pp.32~41 (2012)
  22. Takeuchi Y, "Renal phosphate reabsorption is correlated with the increase in lumbar bone mineral density in patients receiving once-weekly teriparatide", Calcif. Tissue Int, 98, pp.186~192 (2016)
  23. Ozeraitiene V, "The evaluation of bone mineral density based on nutritional status, age, and anthropometric parameters in elderly women", Medicina, 42, pp.836~842 (2006)
  24. Blahos J, "Alternate-day betamethasone treatment does not affect intestinal absorption of calcium and phosphate and growth rate of chicks", Endocrinol Exp, 15, pp.199~204 (1981)
  25. Fox J, "Stimulation of duodenal and ileal absorption of phosphate in the chick", Calcif Tissue Res, 26, pp.243~245 (1978)
  26. Yan F, "Characterization of the chicken small intestine type IIb sodium phosphate cotransporter", Poult Sci, 86, pp.67~76 (2007)
  27. Radanovic T, "Regulation of intestinal phosphate transport I. Segmental expression and adaptation to low-Pi diet of the type IIb Na+-Pi cotransporter in mouse small intestine", Am J Physiol-Gastr L, 288, pp.G496~G500 (2005)
  28. Borowitz SM, "Ontogeny of intestinal phosphate absorption in rabbits", Am J Physiol, 262, pp.G847~G853 (1992)
  29. Wang B, "Regulation of the type IIb sodium-dependent phosphate cotransporter expression in the intestine", Front Agr China, 3, pp.226~230 (2009)
  30. Zhao B, "1,25(OH)2D3-mediated phosphate uptake in isolated chick intestinal cells: Effect of 24,25(OH)2D3, signal transduction activators, and age", J Cell Biochem, 86, pp.497~508 (2002)
  31. Nemere I, "Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells", Proc Natl Acad Sci USA, 101, pp.7392~7397 (2004)
  32. Tunsophon S, "Protein kinase C isotypes in signal transduction for the 1,25D3-MARRS receptor (ERp57", PDIA3) in steroid hormone-stimulated phosphate uptake, 2010, pp.75, 307~313
  33. Brenza HL, "Parathyroid hormone activation of the 25-hydroxyvitamin D3-1α-hydroxylase gene promoter", Proc Natl Acad Sci USA, 95, pp.1387~1391 (1998)
  34. Yu L, "Gene cloning, sequencing and eukaryotic expression plasmid construction of chicken calbindin-D28k", Chin J Anim Vet Sci, 39, pp.1329~1335 (2008)
  35. Tryfonidou MA, "Intestinal calcium absorption in growing dogs is influenced by calcium intake and age but not by growth rate", J Nutr, 132, pp.3363~3368 (2002)
  36. Adriana VP, "Minireview on regulation of intestinal calcium absorption emphasis on molecular mechanisms of transcellular pathway", Int J Gastroenterol, 77, pp.22~34 (2008)
  37. Richard JW, "Intestinal calcium absorption in the aged rat: evidence of intestinal resistance to 1,25(OH)2 vitamin D", Endocrinology, 139, pp.3843~3848 (1998)
  38. Armbrecht HJ, "Differences in intestinal calcium and phosphate transport between low and high bone density mice", Gastr L, 282, pp.G130~G136 (2002)
  39. Dobado-Berrios PM, "Age-related changes of plasma alkaline phosphatase and inorganic phosphorus, and late ossification of the cranial roof in the spanish imperial eagle (Aquila adalberti C. L. Brehm, 1861)", Physiol Zool, 70, pp.421~427 (1997)
  40. Bergwitz C, "Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23", Annu Rev Med, 61, pp.91~104 (2010)

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