Current status and prospects for in-feed antibiotics in the different stages of pork production — A review
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Antibiotics have long been of great benefit for people, both in the medical treatment of human disease and in animal food where they improve the growth performance and feed utilization during animal production. Antibiotics as in-feed supplements affect all stages of pork production, including the gestation, nursing, growing, and finishing stages, although the effects show stage-dependent differences. However, the use of antibiotics in animal feed has become a worldwide concern. This review describes why sub-therapeutic levels of antibiotic additives in animal feed have become an integral part of animal feeding programs for more than 70 years, particularly in pork production. It also discusses the threat of the long-term use of sub-therapeutic levels of antibiotics in pork production. In recent years, the effectiveness of in-feed antibiotics has tended to decrease. This review analyzes this change from various perspectives. First, the equipment used at pig farms has improved dramatically and is more sanitary. Worldwide, more pig farms use pig farrowing crates, gestation crates, piglet nursery crates, flooring devices, piggery ventilation and cooler systems, automatic pig feeders, piggery heating equipment, and artificial insemination systems. In addition, scientists have replaced the use of antibiotics with organic acids, fermented mash, probiotics, prebiotics, minerals, oligosaccharides, enzymes, herbs/flavors, and protein/amino acids, and have improved management and husbandry techniques. In addition, animal welfare legislation has been aimed at improving the quality of the floors and living space, ensuring that animals have permanent access to fresh water, and setting a minimum weaning age. Finally, the prospects and the possibility of replacing antibiotics in pork production are described, in line with recent research results.
Abstract
Antibiotics have long been of great benefit for people, both in the medical treatment of human disease and in animal food where they improve the growth performance and feed utilization during animal production. Antibiotics as in-feed supplements affect all stages of pork production, including the gestation, nursing, growing, and finishing stages, although the effects show stage-dependent differences. However, the use of antibiotics in animal feed has become a worldwide concern. This review describes why sub-therapeutic levels of antibiotic additives in animal feed have become an integral part of animal feeding programs for more than 70 years, particularly in pork production. It also discusses the threat of the long-term use of sub-therapeutic levels of antibiotics in pork production. In recent years, the effectiveness of in-feed antibiotics has tended to decrease. This review analyzes this change from various perspectives. First, the equipment used at pig farms has improved dramatically and is more sanitary. Worldwide, more pig farms use pig farrowing crates, gestation crates, piglet nursery crates, flooring devices, piggery ventilation and cooler systems, automatic pig feeders, piggery heating equipment, and artificial insemination systems. In addition, scientists have replaced the use of antibiotics with organic acids, fermented mash, probiotics, prebiotics, minerals, oligosaccharides, enzymes, herbs/flavors, and protein/amino acids, and have improved management and husbandry techniques. In addition, animal welfare legislation has been aimed at improving the quality of the floors and living space, ensuring that animals have permanent access to fresh water, and setting a minimum weaning age. Finally, the prospects and the possibility of replacing antibiotics in pork production are described, in line with recent research results.
참고문헌 (55)
- "From Wikipedia"[URL]
- "Riots, rage and resistance. A brief history of how antibiotics arrived on the farm"[URL]
- Becker DE, "The efficacy of various antibacterial agents for stimulating the rate of gain in the pig", Antibiot Chemother, 11, pp.421~426 (1952)
- Cromwell GL, "Why and how antibiotics are used in swine production", Anim Biotechnol, 13, pp.7~27 (2002)
- Pluske JR, "Factors influencing the structure and function of the small intestine in the weaned pig: a review", Livest Prod Sci, 51, pp.215~236 (1997)
- Chattopadhyay MK, "Use of antibiotics as feed additives: a burning question", Front Microbiol, 5, pp.334~ (2014)
- "The paradox of antibiotic feed"[URL]
- Zhu YG, "Diverse and abundant antibiotic resistance genes in Chinese swine farms", Proc Natl Acad Sci USA, 110, pp.3435~3440 (2013)
- Fowler SH, "Some effects of source of protein and an antibiotic on reproductive performance in gilts. protein source and reproduction in gilts", J Anim Sci, 13, pp.949~954 (1954)
- Hays VW, "Effect of lactation length and dietary antibiotics on reproductive performance of sows", J Anim Sci, 46, pp.884~891 (1978)
- Messersmith RE, "Value of chlortetracycline in breeding rations for sows", J Anim Sci, 25, pp.752~755 (1966)
- Myers DJ, "Effects of an antibiotic and flushing on performance of sows with short farrowing intervals", J Anim Sci, 36, pp.1125~1128 (1973)
- Ruiz ME, "Effect of feed intake and antibiotic on reproduction in gilts", J Anim Sci, 27, pp.1602~1606 (1968)
- Cranwell PD, "Biological limitations imposed by the digestive system to the growth performance of weaned pigs", Manipulating pig production II Proceedings of the Biennial Conference of the Australasian Pig Science Association APSA held in Albury, pp.140~159 (1989)
- Ravindran V, "Acidification of weaner pig diets: a review", J Sci Food Agric, 62, pp.313~322 (1993)
- Kenworthy R, "The intestinal flora of young pigs, with reference to early weaning, Escherichia coli and scours", J Comp Pathol Ther, 73, pp.215~228 (1963)
- Manners MJ, "Milk replacers for piglets", J Sci Food Agric, 21, pp.333~340 (1970)
- Nabuurs MJA, "Villus height and crypt depth in weaned and unweaned pigs, reared under various circumstances in the Netherlands", Res Vet Sci, 55, pp.78~84 (1993)
- Tsukahara T, "High-sensitivity detection of short-chain fatty acids in porcine ileal, cecal, portal and abdominal blood by gas chromatography-mass spectrometry", Anim Sci J, 85, pp.494~498 (2014)
- Edwards SJ, "Effect of streptomycin on the growth rate and intestinal flora (Escherichia coli) of piglets", J Comp Pathol Ther, 71, pp.243~252 (1961)
- Thymann T, "Antimicrobial treatment reduces intestinal microflora and improves protein digestive capacity without changes in villous structure in weanling pigs", Br J Nutr, 97, pp.1128~1137 (2007)
- Saunders CN, "Escherichia coli infection in piglets", Res Vet Sci, 1, pp.28~35 (1960)
- "Reference of Swine Health & Health Management in the United States. USDA Animal Health and Inspection Service 2012"[URL]
- "Agricultural Research", J R Inst Chem, 9, pp.437~500 (1954)
- Stokstad ELR, "Growth-promoting effect of Aureomycin on turkey poults", Res Notes, 29, pp.611~612 (1950)
- McGinnis J, "Response of chicks and turkey poults to vitamin B12 supplements produced by fermentation with different organisms", Proceedings of the 116th Meeting of the Am Chem Soc (1949)
- Luecke RW, "The growth promoting effects of various antibiotics on pigs", J Anim Sci, 10, pp.538~542 (1951)
- Antibiotics in growing and fattening pig rations. South Dakota State University Open PRAIRIE: Open Public Research Access Institutional Repository and Information Exchange, "Wahlstrom RC", 3~12 (1955)
- Cuff PWW, "Effect of different antibiotics on growing-fatting swine", Iowa State Coll J Sci, 25, pp.575~ (1951)
- "Antibiotic Resistance. October 2016. View Article Online"[URL]
- Flanders T, "A review of antibiotic use in food animals: perspective, policy, and potential", Public Health Rep, 127, pp.4~22 (2012)
- "General background: antibiotic resistance, a societal problem"[URL]
- Delamater ED, "Preliminary report of an outbreak of streptococcal disease caused by a sulfadiazine resistant group A, type 17 hemolytic streptococcus", J Infect Dis, 78, pp.118~127 (1946)
- Campagnolo ER, "Antimicrobial residues in animal waste and water resources proximal to large-scale swine and poultry feeding operations", Sci Total Environ, 299, pp.89~95 (2002)
- Cotta MA, "Isolation, characterization and comparison of bacteria from swine faeces and manure storage pits", Environ Microbiol, 5, pp.737~745 (2003)
- Whitehead TR, "Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes", J Appl Microbiol, 56, pp.264~267 (2013)
- Kumarasamy KK, "Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study", Lancet Infect Dis, 10, pp.597~602 (2010)
- Endoh M, "Two nosocomial outbreaks of sepsis caused by Serratia marcescens, which occurred in July 1999 and January 2002-Tokyo", Kansenshogaku Zasshi, 78, pp.295~304 (2004)
- Visek WJ, "The mode of growth promotion by antibiotics", J Anim Sci, 46, pp.1447~1469 (1978)
- Anderson DB, "Gut microbiology and growth-promoting antibiotics in swine", Pig News Inf, 20, pp.115~122 (1999)
- Bassaganya-Riera J, "Effects of dietary conjugated linoleic acid in nursery pigs of dirty and clean environments on growth, empty body composition, and immune competence", J Anim Sci, 79, pp.714~721 (2001)
- Emborg HD, "The effect of discontinuing the use of antimicrobial growth promoters on the productivity in the Danish broiler production", Prev Vet Med, 50, pp.53~70 (2001)
- Coates ME, "The effect of antibiotics on the intestine of the chick", Br J Nutr, 9, pp.110~119 (1955)
- Laine T, "The effect of antimicrobial growth promoter withdrawal on the health of weaned pigs in Finland", Prev Vet Med, 66, pp.163~174 (2004)
- Coates ME, "A comparison of the growth of chicks in the Gustafsson germ-free apparatus and in a conventional environment, with and without dietary supplements of penicillin", Br J Nutr, 17, pp.141~151 (1963)
- Mroz Z, "Organic acids as potential alternatives to antibiotic growth promoters for pigs", Adv Pork Prod, 16, pp.169~182 (2005)
- Zheji Li, "Effects of Organic Acids on Growth Performance, Gastrointestinal pH, Intestinal Microbial Populations and Immune Responses of Weaned Pigs", ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 21(2), pp.252~261 (2008), 아세아·태평양축산학회
- Leon Broom, "Organic acids promote favorable indigenous intestinal microbiota", Pig international, 44(7), pp.24~ (2014)
- Goodband B, "Practical starter pig amino acid requirements in relation to immunity, gut health and growth performance", J Anim Sci Biotechnol, 5, pp.12~ (2014)
- Riduan SN, "Ultrafast killing and self-gelling antimicrobial imidazolium oligomers", Small, 12, pp.1928~1934 (2016)
- "Global Action Plan on Antimicrobial Resistance. Infection prevention and control 2015. View Article Online"[URL]
- Pradella G, "Antibiotic ban in the European Union. Workshop III: 2006 EU ban on antibiotics as feed additives: Consequences and perspectives", J Vet Pharmacol Ther, 29(Suppl 1), pp.41~46 (2006)
- "National Action Plan for Combating Antibiotic-Resistant Bacteria" (2015)[URL]
- "September 2011, at the 29th South East Asia Health Ministers Meeting, by all Member States of the WHO South-East Asia Region"[URL]
- "The state of the world’s antibiotics 2015" (2015)[URL]
