L-Leucine increases the daily body temperature and affords thermotolerance in broiler chicks
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective: Heat stress poses an increasing threat for poultry production. Some amino acids have been found to play critical roles in affording thermotolerance. Recently, it was found that in ovo administration of L-leucine (L-Leu) altered amino acid metabolism and afforded thermotolerance in heat-exposed broiler chicks. Methods: In this study, two doses (35 and 70 μmol/egg) of L-Leu were administered in ovo on embryonic day 7 to determine their effect on rectal temperature (RT), body weight (BW) and thyroid hormones at hatching. Changes in RT, BW, and thermotolerance in post-hatched chicks were also analyzed. Results: It was found that in ovo administration of L-Leu dose-dependently reduced RT and plasma thyroxine (T4) level just after hatching. In post-hatched neonatal broiler chicks, however, the higher dose of L-Leu administered in ovo significantly increased RT without affecting BW gain. In chicks that had been exposed to heat stress, the RT was significantly lowered by in ovo administration of L-Leu (high dose) in comparison with the control chicks under the same high ambient temperature (HT: 35°C±1°C, 120 min). Conclusion: In ovo administration of L-Leu in a high dose contributed to an increased daily body temperature and afforded thermotolerance under HT in neonatal broiler chicks.
Abstract
Objective: Heat stress poses an increasing threat for poultry production. Some amino acids have been found to play critical roles in affording thermotolerance. Recently, it was found that in ovo administration of L-leucine (L-Leu) altered amino acid metabolism and afforded thermotolerance in heat-exposed broiler chicks. Methods: In this study, two doses (35 and 70 μmol/egg) of L-Leu were administered in ovo on embryonic day 7 to determine their effect on rectal temperature (RT), body weight (BW) and thyroid hormones at hatching. Changes in RT, BW, and thermotolerance in post-hatched chicks were also analyzed. Results: It was found that in ovo administration of L-Leu dose-dependently reduced RT and plasma thyroxine (T4) level just after hatching. In post-hatched neonatal broiler chicks, however, the higher dose of L-Leu administered in ovo significantly increased RT without affecting BW gain. In chicks that had been exposed to heat stress, the RT was significantly lowered by in ovo administration of L-Leu (high dose) in comparison with the control chicks under the same high ambient temperature (HT: 35°C±1°C, 120 min). Conclusion: In ovo administration of L-Leu in a high dose contributed to an increased daily body temperature and afforded thermotolerance under HT in neonatal broiler chicks.
참고문헌 (28)
- Geraert PA, "Metabolic and endocrine changes induced by chronic heatexposure in broiler chickens : growth performance, body composition and energy retention", Br J Nutr, 75, pp.195~204 (1996)
- Azad MA, "Electrolysed reduced water decreases reactive oxygen species-induced oxidative damage to skeletal muscle and improves performance in broiler chickens exposed to medium-term chronic heat stress", Br Poult Sci, 54, pp.503~509 (2013)
- Chowdhury VS, "Oxidative damage and brain concentrations of free amino acid in chicks exposed to high ambient temperature", Comp Biochem Physiol A Mol Integr Physiol, 169, pp.70~76 (2014)
- Ito K, "Changes in free amino acid concentrations in the blood, brain and muscle of heat-exposed chicks", Br Poult Sci, 55, pp.644~652 (2014)
- Chowdhury VS, "Oral administration of L-citrulline, but not L-arginine or L-ornithine, acts as a hypothermic agent in chicks", J Poult Sci, 52, pp.331~335 (2015)
- Chowdhury VS, "L-Citrulline acts as potential hypothermic agent to afford thermotolerance in chicks", J Therm Biol, 69, pp.163~170 (2017)
- Han G, "L-Leucine acts as a potential agent in reducing body temperature at hatching and affords thermotolerance in broiler chicks", Comp Biochem Physiol A Mol Integr Physiol, 204, pp.48~56 (2017)
- Han G, "In ovo L-leucine administration stimulates lipid metabolisms in heat-exposed male, but not female, chicks to afford thermotolerance", J Therm Biol, 71, pp.74~82 (2018)
- Chowdhury VS, "Heat stress biomarker amino acids and neuropeptide afford thermotolerance in chicks", J Poult Sci, 56, pp.1~11 (2019)
- 김동희, "Effect of BCAA intake during endurance exercises on fatigue substances, muscle damage substances, and energy metabolism substances", Physical Activity and Nutrition, 17(4), pp.169~180 (2013), 한국운동영양학회
- Green CR, "Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis", Nat Chem Biol, 12, pp.15~21 (2016)
- Piestun Y, "The effect of thermal manipulations during the development of the thyroid and adrenal axes on in-hatch and post-hatch thermoregulation", J Therm Biol, 33, pp.413~418 (2008)
- McNabb FMA, "Sturkie’s avian physiology", pp.535~547 (2015), Academic Press
- Yahav S, "Sturkie’s avian physiology", pp.869~905 (2015), Academic Press
- Piestun Y, "Thermal manipulations of broiler embryos-the effect on thermoregulation and development during embryogenesis", Poult Sci, 88, pp.2677~2688 (2009)
- Chowdhury VS, "Physiological and behavioral responses of young chicks to high ambient temperature", J Poult Sci, 49, pp.212~218 (2012)
- Kobayashi K, "A handbook of applied statistics in pharmacology", pp.37~46 (2013), CRC Press
- Piestun Y, "Thermal manipulations of turkey embryos : the effect on thermoregulation and development during embryogenesis", Poult Sci, 94, pp.273~280 (2015)
- Danforth E, "The role of thyroid hormones in the control of energy expenditure", Clin Endocrinol Metab, 13, pp.581~595 (1984)
- Wentworth BC, "Avian physiology", pp.452~465 (1986), Springer
- Willemsen H, "High-and low-temperature manipulation during late incubation : effects on embryonic development, the hatching process, and metabolism in broilers", Poult Sci, 89, pp.2678~2690 (2010)
- Takahashi H, "Regulation of body temperature by thyrotropin-releasing hormone in neonatal chicks", Dev Brain Res, 157, pp.58~64 (2005)
- De Basilio V, "Early age thermal conditioning immediately reduces body temperature of broiler chicks in a tropical environment", Poult Sci, 82, pp.1235~1241 (2003)
- Arad Z, "Ontogeny of brain temperature in quail chicks(Coturnix coturnix japonica)", Physiol Zool, 64, pp.1356~1370 (1991)
- Hillman PE, "Stress physiology in livestock", pp.27~71 (1985), CRC Press
- Mujahid A, "Mitochondrial oxidative damage in chicken skeletal muscle induced by acute heat stress", J Poult Sci, 44, pp.439~445 (2007)
- Tanizawa H, "Effect of short-term thermal conditioning on physiological and behavioral responses to subsequent acute heat exposure in chicks", J Poult Sci, 51, pp.80~86 (2014)
- Aggarwal A, "Heat stress and animal productivity" (2012), Springer