Studies on phosphorus deficiency in the Qianbei-Pockmarked goat
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Objective: Qianbei-Pockmarked goats are affected by a disorder locally referred to as ‘Ruanguzheng Disorder’, which is characterized by emaciation, lameness, muscular relaxation, stiffness of the extremities, and abnormal curvatures of the long bones. Our objective was to determine the relationship between the disorder and phosphorus deficiency. Methods: Tissue samples were collected from affected and healthy animals, while soil and herbage samples were collected from affected and healthy pastures. Biochemical parameters were determined using an automatic biochemical analyzer (OLYMPUS AU 640, Olympus Optical Co., Tokyo, Japan). Mineral contents in soil, forage, and tissue were determined using a Perkin-Elmer AAS5000 atomic absorption spectrophotometer (Perkin-Elmer, Norwalk, CT, USA). Results: The results showed that phosphorus contents in herbages from affected pastures were markedly lower than those from healthy areas (p<0.01), and the ratio of calcium to phosphorus in the affected herbages was 12.93:1. The phosphorus contents of wool, blood, tooth, and bone from affected animals were also markedly lower than those from healthy animals (p<0.01). Serum phosphorus values in affected animals were much lower than those in healthy animals, while serum alkaline phosphatase values from affected animals were markedly higher than those from healthy animals (p<0.01). Inorganic phosphorus values from affected animals were approximately half of that in the control group. Supplementation of disodium hydrogen phosphate prevented and cured the disorder. Conclusion: This study demonstrates that Ruanguzheng disorder in Qianbei-Pockmarked goats is primarily caused by phosphorus deficiencies in herbage due to fenced pastures and natural habitat fragmentation.
Abstract
Objective: Qianbei-Pockmarked goats are affected by a disorder locally referred to as ‘Ruanguzheng Disorder’, which is characterized by emaciation, lameness, muscular relaxation, stiffness of the extremities, and abnormal curvatures of the long bones. Our objective was to determine the relationship between the disorder and phosphorus deficiency. Methods: Tissue samples were collected from affected and healthy animals, while soil and herbage samples were collected from affected and healthy pastures. Biochemical parameters were determined using an automatic biochemical analyzer (OLYMPUS AU 640, Olympus Optical Co., Tokyo, Japan). Mineral contents in soil, forage, and tissue were determined using a Perkin-Elmer AAS5000 atomic absorption spectrophotometer (Perkin-Elmer, Norwalk, CT, USA). Results: The results showed that phosphorus contents in herbages from affected pastures were markedly lower than those from healthy areas (p<0.01), and the ratio of calcium to phosphorus in the affected herbages was 12.93:1. The phosphorus contents of wool, blood, tooth, and bone from affected animals were also markedly lower than those from healthy animals (p<0.01). Serum phosphorus values in affected animals were much lower than those in healthy animals, while serum alkaline phosphatase values from affected animals were markedly higher than those from healthy animals (p<0.01). Inorganic phosphorus values from affected animals were approximately half of that in the control group. Supplementation of disodium hydrogen phosphate prevented and cured the disorder. Conclusion: This study demonstrates that Ruanguzheng disorder in Qianbei-Pockmarked goats is primarily caused by phosphorus deficiencies in herbage due to fenced pastures and natural habitat fragmentation.
참고문헌 (36)
- Shen XY, "Studies on serum biochemical values and mineral contents of tissues in Qianbei-pockmarked goats", J Anim Vet Adv, 13, pp.503~505 (2014)
- Shupe JL, "Clinical signs and bone change associated with phosphorus deficiency in beef cattle", Am J Vet Res, 49, pp.1619~1636 (1988)
- Heuer C, "Variation of serum inorganic phosphorus and association with haemoglobinuria and osteomalacia in female water buffaloes in Pakistan", Prev Vet Med, 33, pp.69~81 (1998)
- McDowell LR, "Minerals in animal and human nutrition", pp.770~ (1992), Academic Press Inc
- Parker VJ, "Association of vitamin D metabolites with parathyroid hormone, fibroblast growth factor-23, calcium, and phosphorus in dogs with various stages of chronic kidney disease", J Vet Intern Med, 31, pp.791~798 (2017)
- Liu Z, "Studies on rickets and osteomalacia in Bactrian camels (Camelus bactrianus)", Vet J, 169, pp.444~453 (2005)
- Shen X, "Phosphorus metabolic disorder of Guizhou semi-fine wool sheep", Plos One, 9, pp.e89472~ (2014)
- Federation of Animals Science Societies, "Guide for the care and use of agricultural animals in research and teaching", FASS, 169~ (2010)
- Wang K, "Trace element in life science", pp.1040~ (1996), Metrology Press
- Salmela S, "The effect of washing procedures on trace element content of human hair", Anal Chim Acta, 125, pp.131~137 (1981)
- Shen X, "Copper deficiency in yaks on pasture in western China", Can Vet J, 47, pp.902~906 (2006)
- Shen X, "Studies on “Stiffness of Extremities Disease” in the Yak (Bos mutus)", J Wildl Dis, 48, pp.542~547 (2012)
- Yuan R, "Copper deficiency in Guizhou semi-fine wool sheep on pasture in south west China karst mountain area", Afr J Biotechnol, 10, pp.17043~17048 (2011)
- Huang Y, "Studies on the pathogenesis of Shimao Zheng(Fleece-eating)in sheep and goats", Vet Res Commun, 25, pp.631~640 (2001)
- Shen X, "Studies of wool-eating ailment in Guizhou semi-fine wool sheep", Agric Sci China, 10, pp.1618~1623 (2011)
- Huang Y, "An experimental study on the treatment and prevention of shimao zheng(fleece-eating)in sheep and goats in the Haizi area of Akesai County in China", Vet Res Commun, 26, pp.39~48 (2002)
- Burk RF, "Selenium deficiency occurs in some patients with moderate-to-severe cirrhosis and can be corrected by administration of selenate but not selenomethionine : a randomized controlled trial", Am J Clin Nutr, 102, pp.1126~1133 (2015)
- Scott D, "The effect of variation in phosphorus intake on net intestinal phosphorus absorption, salivary phosphorus secretion and pathway of excretion in sheep fed roughage diets", Q J Exp Physiol, 69, pp.439~452 (1984)
- Scott D, "Factors affecting faecal endogenous phosphorus loss in the sheep", J Agric Sci, 124, pp.145~151 (1995)
- Arthington JD, "Effect of ammonium sulfate fertilization on bahiagrass quality and copper metabolism in grazing beef cattle", J Anim Sci, 80, pp.2507~2512 (2002)
- Tiffany ME, "Effects of residual and reapplied biosolids on performance and mineral status of grazing beef steers", J Anim Sci, 80, pp.260~269 (2002)
- Field AC, "The effect of dietary intake of calcium and dry matter on the absorption and excretion of calcium and phosphorus by growing lambs", J Agric Sci, 105, pp.237~243 (1985)
- Karn JF, "Phosphorus nutrition of grazing cattle : a review", Anim Feed Sci Technol, 89, pp.133~153 (2001)
- Suttle NF, "Mineral nutrition of livestock", pp.579~ (2010), CABI Publishing
- Wang J, "Veterinary clinical diagnosis", pp.373~ (2004), Chinese Agricultural Press
- Scott D, "The effect of feeding either roughage or concentrate diets on salivary phosphorus secretion, net intestinal phosphorus absorption and urinary phosphorus excretion in the sheep", Q J Exp Physiol, 70, pp.365~375 (1985)
- Wang Z, "Mineral element metabolism and animal disease", pp.544~ (1995), Shanghai Science-Technology Press
- Maduell F, "Assessment of phosphorus and calcium metabolism and its clinical management in hemodialysis patients in the community of valencia", J Nephrol, 18, pp.739~748 (2005)
- Braithwaite GD, "Endogenous faecal loss of phosphorus in growing lambs and the calculation of phosphorus requirements", J Agric Sci, 105, pp.67~72 (1985)
- Scott D, "The effects of feeding either hay or grass diets on salivary phosphorus secretion, net intestinal phosphorus absorption and on the partition of phosphorus excretion between urine and faeces in the sheep", Q J Exp Physiol, 72, pp.331~338 (1987)
- Sakuma M, "Soymilk intake has desirable effects on phosphorus and calcium metabolism", J Clin Biochem Nutr, 62, pp.259~263 (2018)
- Mazouri A, "Does adding intravenous phosphorus to parenteral nutrition has any effects on calcium and phosphorus metabolism and bone mineral content in preterm neonates?", Acta Med Iran, 55, pp.395~398 (2017)
- Kauv P, "Adenosine triphosphate metabolism measured by phosphorus magnetic resonance spectroscopy : a potential biomarker for multiple sclerosis severity", Eur Neurol, 77, pp.316~321 (2017)
- Ferrier-Pagès C, "Phosphorus metabolism of reef organisms with algal symbionts", Ecol Monogr, 86, pp.262~277 (2016)
- Adedokun SA, "Calcium and phosphorus digestibility : metabolic limits", J Appl Poult Res, 22, pp.600~608 (2013)
- Liu SX, "The effect of bovine parathyroid hormone withdrawal on MC3T3-E1 cell proliferation and phosphorus metabolism", Plos One, 10, pp.e0120402~ (2015)