Comparison of Autonomic Reactivity to the Stress between Adjustment Disorder and Major Depressive Disorder
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective Adjustment disorder (AD) remains an ambiguous diagnosis that overlaps with major depressive disorder (MDD). This study compared autonomic reactivity to the stress between AD and MDD to test for biological differences.Methods Physically healthy Korean male soldiers admitted to a psychiatric ward were recruited for participation. Clinical diagnoses indicated that 62 patients with AD and 47 with MDD were selected. Procedures consisted of electrocardiogram measurements according to three consecutive phases lasting five minutes each [i.e., resting, stress (including a mental arithmetic task and Stroop color word test), and recovery].Results The reactive trends of all heart rate variability (HRV) parameters related to the stress tasks in participants with AD did not differ from those with MDD. High-frequency HRV (a proxy of parasympathetic activity) increased during times of stress for participants with AD and MDD. Despite similar reactive trends, AD participants had higher HRV values than participants with MDD during whole phases, particularly for variables reflecting overall autonomic activity.Conclusion AD is associated with higher basal activity in the autonomous nervous system when compared to MDD. However, both are associated with pathophysiology indicating an altered autonomic reactivity to stress.
Abstract
Objective Adjustment disorder (AD) remains an ambiguous diagnosis that overlaps with major depressive disorder (MDD). This study compared autonomic reactivity to the stress between AD and MDD to test for biological differences.Methods Physically healthy Korean male soldiers admitted to a psychiatric ward were recruited for participation. Clinical diagnoses indicated that 62 patients with AD and 47 with MDD were selected. Procedures consisted of electrocardiogram measurements according to three consecutive phases lasting five minutes each [i.e., resting, stress (including a mental arithmetic task and Stroop color word test), and recovery].Results The reactive trends of all heart rate variability (HRV) parameters related to the stress tasks in participants with AD did not differ from those with MDD. High-frequency HRV (a proxy of parasympathetic activity) increased during times of stress for participants with AD and MDD. Despite similar reactive trends, AD participants had higher HRV values than participants with MDD during whole phases, particularly for variables reflecting overall autonomic activity.Conclusion AD is associated with higher basal activity in the autonomous nervous system when compared to MDD. However, both are associated with pathophysiology indicating an altered autonomic reactivity to stress.
참고문헌 (47)
- Mitchell AJ, "Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings : a meta-analysis of 94interview-based studies", Lancet Oncol, 12, pp.160~174 (2011)
- Popkin MK, "Adjustment disorders in medically ill inpatients referred for consultation in a university hospital", Psychosomatics, 31, pp.410~414 (1990)
- Reed GM, "Mental health professionals’ natural taxonomies of mental disorders : implications for the clinical utility of the ICD-11 and the DSM-5", J Clin Psychol, 69, pp.1191~1212 (2013)
- Silverstone PH, "Prevalence of psychiatric disorders in medical inpatients", J Nerv Ment Dis, 184, pp.43~51 (1996)
- Casey PR, "Factors associated with suicidal ideation in the general population : five-centre analysis from the ODIN study", Br J Psychiatry, 189, pp.410~415 (2006)
- Kryzhanovskaya L, "Suicidal behavior in patients with adjustment disorders", Crisis, 22, pp.125~131 (2001)
- Lonnqvist JK, "Mental disorders and suicide prevention", Psychiatry Clin Neurosci, 49(Suppl 1), pp.S111~S116 (1995)
- Taggart C, "Accuracy of diagnosis at routine psychiatric assessment in patients presenting to an accident and emergency department", Gen Hosp Psychiatry, 28, pp.330~335 (2006)
- Ministry of National Defense, "The Epidemiological Survey of Psychiatric Illnesses in Military Service" (2007), Ministry of National Defense
- Maercker A, "Adjustment disorders : prevalence in a representative nationwide survey in Germany", Soc Psychiatry Psychiatr Epidemiol, 47, pp.1745~1752 (2012)
- Strain JJ, "Considering adjustment disorders as stress response syndromes for DSM-5", Depress Anxiety, 28, pp.818~823 (2011)
- Bronisch T, "Adjustment reactions : a long-term prospective and retrospective follow-up of former patients in a crisis intervention ward", Acta Psychiatr Scand, 84, pp.86~93 (1991)
- Despland JN, "Clinical relevance of adjustment disorder in DSM-III-4 and DSM-IV", Compr Psychiatry, 36, pp.454~460 (1995)
- Jones R, "Readmission rates for adjustment disorders : comparison with other mood disorders", J Affect Disord, 71, pp.199~203 (2002)
- Looney JG, "Transient situational disturbances : course and outcome", Am J Psychiatry, 135, pp.660~663 (1978)
- Snyder S, "Differentiating major depression from adjustment disorder with depressed mood in the medical setting", Gen Hosp Psychiatry, 12, pp.159~165 (1990)
- Barnow S, "The importance of psychosocial factors, gender, and severity of depression in distinguishing between adjustment and depressive disorders", J Affect Disord, 72, pp.71~78 (2002)
- Casey P, "Can adjustment disorder and depressive episode be distinguished? Results from ODIN", J Affect Disord, 92, pp.291~297 (2006)
- Fernandez A, "Adjustment disorders in primary care : prevalence, recognition and use of services", Br J Psychiatry, 201, pp.137~142 (2012)
- Banki CM, "Biochemical markers in suicidal patients. Investigations with cerebrospinal fluid amine metabolites and neuroendocrine tests", J Affect Disord, 6, pp.341~350 (1984)
- Lindqvist D, "Suicidal intent and the HPAaxis characteristics of suicide attempters with major depressive disorder and adjustment disorders", Arch Suicide Res, 12, pp.197~207 (2008)
- Ader R, "Psychoneuroimmunology : interactions between the nervous system and the immune system", Lancet, 345, pp.99~103 (1995)
- Oh DJ, "Altered autonomic reactivity in Korean military soldiers with adjustment disorder", Psychiatry Res, 261, pp.428~435 (2018)
- Marques AH, "Evaluation of stress systems by applying noninvasive methodologies : measurements of neuroimmune biomarkers in the sweat, heart rate variability and salivary cortisol", Neuroimmunomodulation, 17, pp.205~208 (2010)
- Yeragani VK, "Major depression with ischemic heart disease : effects of paroxetine and nortriptyline on longterm heart rate variability measures", Biol Psychiatry, 52, pp.418~429 (2002)
- Task Force of the European Society of Cardiology, "Heart rate variability: standards of measurement, physiological interpretation and clinical use", Circulation, 93, pp.1043~1065 (1996)
- Cho MJ, "Use of the Center for Epidemiologic Studies Depression(CES-D)Scale in Korea", J Nerv Ment Dis, 186, pp.304~310 (1998)
- 이한경, "Psychometric Properties of the Beck Anxiety Inventory in the Community-dwelling Sample of Korean Adults", Korean Journal of Clinical Psychology, 35(4), pp.822~830 (2016), 한국임상심리학회[DOI]
- 이종하, "한글판 스트레스 자각척도의 신뢰도와 타당도 연구", 정신신체의학, 20(2), pp.127~134 (2012), 한국정신신체의학회
- 이혜선, "한국판 자살생각척도(K-BSI)의 타당화 연구", Korean Journal of Clinical Psychology, 28(4), pp.1155~1172 (2009), 한국임상심리학회[DOI]
- Laborde S, "Heart rate variability and cardiac vagal tone in psychophysiological research-recommendations for experiment planning, data analysis, and data reporting", Front Psychol, 8, pp.213~ (2017)
- Visnovcova Z, "Complexity and time asymmetry of heart rate variability are altered in acute mental stress", Physiol Meas, 35, pp.1319~1334 (2014)
- Schiweck C, "Heart rate and high frequency heart rate variability during stress as biomarker for clinical depression. A systematic review", Psychol Med, 49, pp.200~211 (2019)
- Lackner HK, "Phase synchronization of hemodynamic variables and respiration during mental challenge", Int J Psychophysiol, 79, pp.401~409 (2011)
- Papousek I, "Trait and state positive affect and cardiovascular recovery from experimental academic stress", Biol Psychol, 83, pp.108~115 (2010)
- Hjortskov N, "The effect of mental stress on heart rate variability and blood pressure during computer work", Eur J Appl Physiol, 92, pp.84~89 (2004)
- Taelman J, "Instantaneous changes in heart rate regulation due to mental load in simulated office work", Eur J Appl Physiol, 111, pp.1497~1505 (2011)
- Reyes del Paso GA, "The utility of low frequency heart rate variability as an index of sympathetic cardiac tone : a review with emphasis on a reanalysis of previous studies", Psychophysiology, 50, pp.477~487 (2013)
- Shaffer F, "A healthy heart is not a metronome : an integrative review of the heart’s anatomy and heart rate variability", Front Psychol, 5, pp.1040~ (2014)
- Shaffer F, "An overview of heart rate variability metrics and norms", Front Public Health, 5, pp.258~ (2017)
- Liang CS, "Reactive heart rate variability in male patients with first-episode major depressive disorder", Prog Neuropsychopharmacol Biol Psychiatry, 56, pp.52~57 (2015)
- Kop WJ, "Autonomic nervous system dysfunction and inflammation contribute to the increased cardiovascular mortality risk associated with depression", Psychosom Med, 72, pp.626~635 (2010)
- Lampert R, "Decreased heart rate variability is associated with higher levels of inflammation in middle-aged men", Am Heart J, 156, pp.759 e1~759 e7 (2008)
- Kemp AH, "Impact of depression and antidepressant treatment on heart rate variability : a review and meta-analysis", Biol Psychiatry, 67, pp.1067~1074 (2010)
- Licht CM, "Longitudinal evidence for unfavorable effects of antidepressants on heart rate variability", Biol Psychiatry, 68, pp.861~868 (2010)
- Licht CM, "Effects of antidepressants, but not psychopathology, on cardiac sympathetic control : a longitudinal study", Neuropsychopharmacology, 37, pp.2487~2495 (2012)
- Seeman TE, "Price of adaptation--allostatic load and its health consequences. MacArthur studies of successful aging", Arch Intern Med, 157, pp.2259~2268 (1997)
