소아에서 출혈성 수포를 동반한 Henoch-Sch？nlein 자반병 1례
A Case of Henoch-Sch？lein Purpura with Hemorrhagic Bullae in a Child
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Henoch-Schonlein 자반증은 소혈관의 혈관염으로 오는 전신적 혈관 장애로 자반, 위장 증세, 관절 증세, 신 증세를 주 증세로 하는 질환이다. HSP의 흔한 피부증상은 주로 궁둥이와 하지의 자반 증상이며 성인에서는 출혈성 수포를 동반하는 경우가 흔하나 소아에서는 드문 것으로 알려져 있다. 저자들은 관절통과 복통을 호소하는 환아에서 출혈성 수포가 동반되어 있어 피부조직 검사를 하였고 진피의 leukocytoclastic vasculitis와 면역 형광법상 소혈관의 IgA와 fibrinogen의 침착을 관찰하였다. HSP로 진단하여 스테로이드 치료를 하였고 수일 내로 관절통과 복통이 호전되어 문헌고찰과 함께 보고하는 바이다.
Abstract
Henoch-Schönlein purpura(HSP) is a systemic small vessel vasculitis characterized by cutaneous purpura, arthritis, abdominal pain and nephritis. The characteristic rash of HSP consists of palpable purpura on the buttocks and lower extremities. Bullous lesions often appear in adults with HSP, whereas they are very rare in children with HSP. In this case report, the patient presented with arthralgia and abdominal pain and had hemorrhagic bullae as a prominent manifestation of the disease. The skin biopsy of the patient revealed typical leukocytoclastic vasculitis of dermal vessels and prominent IgA and fibrinogen deposits on capillary walls by direct immunofluorescence. We confirmed the diagnosis of HSP and observed improvement of clinical symptoms and signs within a few days after corticosteroid treatment. We therefore report a case with a review of the literature.
참고문헌 (12)
- "Henoch-Sch nlein purpura in children:report of 100 patients and review of the literature", 78, pp.395~409 (1999)
- "Henoch-Schonlein purpura", 13, pp.130~7 (1992)
- "The American College of Rheumatology 1990 criteria for the classification of Henoch- Schonlein purpura", 8, pp.1114~21 (1990)
- "Schonlein-Henoch purpura in adult patients", 133, pp.438~442 (1997)
- "Henoch-Schonlein purpura in Arab children", 42, pp.52~7 (1990)
- "Cutaneous manifestations of Henoch-Schonlein purpura in young children", 15, pp.426~428 (1998)
- "Hemorrhagic bullous lesions in Henoch-Schonlein purpura", 15, pp.357~359 (1998)
- "Dermal and glomerular deposition of IgA in anaphylactoid purpura", 131, pp.981~3 (1977)
- "Use of intravenous hydrocortisone in Henoch-Schonlein purpura", 37, pp.309~310 (2001)
- "Successful treatment of progressive Henoch-Schonlein purpura nephritis with tonsillectomy and steroid pulse therapy", 6, pp.611~615 (2005)
- "Hemorrhagic bullous lesions in Henoch-Schonlein purpura", 47, pp.694~697 (2005)
- "Henoch-Schonlein purpura with hemorrhagic bullae in children:report of two cases", 37, pp.375~378 (2004)