Verbal and Visual Memory Impairments in Bipolar I and II Disorder
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Objective To compare verbal and visual memory performances between patients with bipolar I disorder (BD I) and patients with bipolar II disorder (BD II) and to determine whether memory deficits were mediated by impaired organizational strategies. Methods Performances on the Korean-California Verbal Learning Test (K-CVLT) and the Rey-Osterrieth Complex Figure Test (ROCF)in 37 patients with BD I, 46 patients with BD II and 42 healthy subjects were compared. Mediating effects of impaired organization strategies on poor delayed recall was tested by comparing direct and mediated models using multiple regression analysis. Results Both patients groups recalled fewer words and figure components and showed lower Semantic Clustering compared to controls. Verbal memory impairment was partly mediated by difficulties in Semantic Clustering in both subtypes, whereas the mediating effect of Organization deficit on the visual memory impairment was present only in BD I. In all mediated models, group differences in delayed recall remained significant. ConclusionaaOur findings suggest that memory impairment may be one of the fundamental cognitive deficits in bipolar disorders and that executive dysfunctions can exert an additional influence on memory impairments.
Abstract
Objective To compare verbal and visual memory performances between patients with bipolar I disorder (BD I) and patients with bipolar II disorder (BD II) and to determine whether memory deficits were mediated by impaired organizational strategies. Methods Performances on the Korean-California Verbal Learning Test (K-CVLT) and the Rey-Osterrieth Complex Figure Test (ROCF)in 37 patients with BD I, 46 patients with BD II and 42 healthy subjects were compared. Mediating effects of impaired organization strategies on poor delayed recall was tested by comparing direct and mediated models using multiple regression analysis. Results Both patients groups recalled fewer words and figure components and showed lower Semantic Clustering compared to controls. Verbal memory impairment was partly mediated by difficulties in Semantic Clustering in both subtypes, whereas the mediating effect of Organization deficit on the visual memory impairment was present only in BD I. In all mediated models, group differences in delayed recall remained significant. ConclusionaaOur findings suggest that memory impairment may be one of the fundamental cognitive deficits in bipolar disorders and that executive dysfunctions can exert an additional influence on memory impairments.
참고문헌 (35)
- Robinson LJ., "A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder", J Affect Disord, 93, pp.105~115 (2006)
- Torres IJ., "Neurocognitive functioning in patients with bipolar I disorder recently recovered from a first manic episode", J Clin Psychiatry, 71, pp.1234~1242 (2010)
- Bora E., "Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives", J Affect Disord, 113, pp.1~20 (2009)
- Savage CR., "Neuropsychology of subcortical dementias", Psychiatr Clin North Am, 20, pp.911~931 (1997)
- Deckersbach T., "The relationship between semantic organization and memory in obsessive-compulsive disorder", Psychother Psychosom, 69, pp.101~107 (2000)
- Penades R., "Executive function and nonverbal memory in obsessive-compulsive disorder", Psychiatry Res, 133, pp.81~90 (2005)
- Deckersbach T., "Episodic memory impairment in bipolar disorder and obsessive- compulsive disorder: the role of memory strategies", Bipolar Disord, 6, pp.233~244 (2004)
- Shin MS., "Deficits of organizational strategy obsessive-compulsive and visual memory in disorder", NEUROPSYCHOLOGY, 18, pp.665~672, AMER PSYCHOLOGICAL ASSOC
- Brebion G., "Semantic organization and verbal memory efficiency in patients with schizophrenia", Neuropsychology, 18, pp.378~383 (2004)
- Bora E., "Voxelwise meta-analysis of gray matter abnormalities in bipolar disorder", Biol Psychiatry, 67, pp.1097~1105 (2010)
- Chen CH., "A quantitative meta-analysis of fMRI studies in bipolar disorder", Bipolar Disorder, 13, pp.1~15 (2011)
- Bearden CE., "Sources of declarative memory impairment in bipolar disorder: mnemonic processes and clinical features", J Psychiatr Res, 40, pp.47~58 (2006)
- Deckersbach T., "Characteristics of non-verbal memory impairment in bipolar disorder: the role of encoding strategies", Psychol Med, 34, pp.823~832 (2004)
- Judd LL., "A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder", Arch Gen Psychiatry, 60, pp.261~269 (2003)
- Merikangas KR., "Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication", Arch Gen Psychiatry, 64, pp.543~552 (2007)
- Maina G., "Health-related quality of life in euthymic bipolar disorder patients: differences between bipolar I and II subtypes", J Clin Psychiatry, 68, pp.207~212 (2007)
- Heun R., "The distinction of bipolar II disorder from bipolar I and recurrent unipolar depression: results of a controlled family study", Acta Psychiatr Scand, 87, pp.279~284 (1993)
- McMahon FJ., "Linkage of bipolar disorder to chromosome 18q and the validity of bipolar II disorder", Arch Gen Psychiatry, 58, pp.1025~1031 (2001)
- Ha TH., "Similarities and differences of white matter connectivity and water diffusivity in bipolar I and II disorder", NEUROSCIENCE LETTERS, 505(2), pp.150~154, ELSEVIER IRELAND LTD
- Ha TH., "Regional brain gray matter abnormalities in patients with bipolar II disorder: a comparison study with bipolar I patients and healthy controls", Neurosci Lett, 456, pp.44~48 (2009)
- Andersson S., "Neuropsychological and electrophysiological indices of neurocognitive dysfunction in bipolar II disorder", Bipolar Disord, 10, pp.888~899 (2008)
- Simonsen C., "Neurocognitive profiles in bipolar I and bipolar II disorder: differences in pattern and magnitude of dysfunction", Bipolar Disord, 10, pp.245~255 (2008)
- Sole B., "Neurocognitive impairment and psychosocial functioning in bipolar II disorder", Acta Psychiatr Scand, 125, pp.309~317 (2012)
- Torrent C., "Cognitive impairment in bipolar II disorder", Br J Psychiatry, 189, pp.254~259 (2006)
- Chang JS., "Differential pattern of semantic memory organization between bipolar I and II disorders", Prog Neuropsychopharmacol Biol Psychiatry, 35, pp.1053~1058 (2011)
- First MB., "Structured Clinical Interview for DSM-IV Axis I Disorder" (1996), New York State Psychiatric Institute
- Sheehan DV., "The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10", J Clin Psychiatry, 59, pp.22~33 (1998)
- Spearing MK., "Modification of the Clinical Global Impressions (CGI) Scale for use in bipolar illness (BP): the CGI-BP", Psychiatry Res, 73, pp.159~171 (1997)
- 김정기, "NORMATIVE STUDY OF THE KOREAN-CALIFORNIA VERBAL LEARNING TEST (K-CVLT)", CLINICAL NEUROPSYCHOLOGIST, 13(3), pp.365~369, SWETS ZEITLINGER PUBLISHERS
- Delis DC., "California Verbal Learning Test Research Edition Manual Adult Version" (1987), The Psychological Corporation
- Rey A., "L’examen psychologique dans les cas d’encephalopathie traumatique", Arch Psychol, 28, pp.286~340 (1941)
- Osterrieth PA., "Le test de copie d’une figure complexe", Arch Psychol, 30, pp.206~356 (1944)
- Stern RA., "The Boston Qualitative Scoring System for the Rey-Osterrieth Complex Figure: Description and interrator reliability", Clin Neuropsychol, 8, pp.309~322 (1994)
- Weschsler D., "Adult Intelligence Scale, Revised (WAIS-R) Manual" (1981), Psychological Corp
- Martino DJ., "Neurocognitive impairments and their relationship with psychosocial functioning in euthymic bipolar II disorder", J Nerv Ment Dis, 199, pp.459~464 (2011)