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Risk Factors for Suicidal Ideation among Patients with Complex Regional Pain Syndrome

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Objective Chronic pain frequently coexists with psychiatric symptoms in patients diagnosed with complex regional pain syndrome(CRPS). Previous studies have shown a relationship between CRPS and the risk of suicide. The purpose of this study was to assess riskfactors for suicidal ideation in patients with CRPS. Methods Based on criteria established by the International Association for the Study of Pain, 39 patients diagnosed with CRPS Type 1or Type 2 were enrolled in this study. Suicidal ideation was assessed using item 3 of the Hamilton Depression Rating Scale (HAMD), andsymptoms of pain were evaluated using the short form of the McGill Pain Questionnaire (SF-MPQ). Psychiatric symptoms were assessedin using the Structured Clinical Interview for DSM-IV Disorders (SCID-I, SCID-II), the HAMD, the Hamilton Anxiety RatingScale (HAMA), the Global Assessment of Functioning Scale (GAF), and the Pittsburgh Sleep Quality Index (PSQI). Results Twenty-nine patients (74.4%) were at high risk and 10 (25.6%) were at low risk for suicidal ideation. Risk factors significantlyassociated with suicidal ideation included depression (p=0.002), severity of pain (p=0.024), and low scores on the GAF (p=0.027). Nosignificant correlations were found between suicidal ideation and anxiety or quality of sleep. Conclusion Significant risk factors for suicidal ideation in patients with CRPS include severity of pain, depressive symptoms, and decreasedfunctioning. These results suggest that psychiatric evaluation and intervention should be included in the treatment of CRPS.

Abstract

Objective Chronic pain frequently coexists with psychiatric symptoms in patients diagnosed with complex regional pain syndrome(CRPS). Previous studies have shown a relationship between CRPS and the risk of suicide. The purpose of this study was to assess riskfactors for suicidal ideation in patients with CRPS. Methods Based on criteria established by the International Association for the Study of Pain, 39 patients diagnosed with CRPS Type 1or Type 2 were enrolled in this study. Suicidal ideation was assessed using item 3 of the Hamilton Depression Rating Scale (HAMD), andsymptoms of pain were evaluated using the short form of the McGill Pain Questionnaire (SF-MPQ). Psychiatric symptoms were assessedin using the Structured Clinical Interview for DSM-IV Disorders (SCID-I, SCID-II), the HAMD, the Hamilton Anxiety RatingScale (HAMA), the Global Assessment of Functioning Scale (GAF), and the Pittsburgh Sleep Quality Index (PSQI). Results Twenty-nine patients (74.4%) were at high risk and 10 (25.6%) were at low risk for suicidal ideation. Risk factors significantlyassociated with suicidal ideation included depression (p=0.002), severity of pain (p=0.024), and low scores on the GAF (p=0.027). Nosignificant correlations were found between suicidal ideation and anxiety or quality of sleep. Conclusion Significant risk factors for suicidal ideation in patients with CRPS include severity of pain, depressive symptoms, and decreasedfunctioning. These results suggest that psychiatric evaluation and intervention should be included in the treatment of CRPS.

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