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Impact of Anxiety and Depression on Physical Health Condition and Disability in an Elderly Korean Population

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초록

Objective: This study aimed to investigate the longitudinal effects of anxiety, depression, and their comorbidity on physical disorders and disability in an elderly Korean population. Methods: In total, 1,204 community-dwelling elders were evaluated at baseline, and of these 909 (75%) were re-assessed two years later. Anxiety and depression were identified at baseline using questions from the community version of the Geriatric Mental State diagnostic schedule (GMS-B3). Participants were assessed for functional disability and for 11 physical disorders both at baseline and at follow-up. Results: Anxiety alone was associated with the incidence of heart disease, depression alone with the incidence of asthma, and comorbid anxiety and depression with incidence of eyesight problem, persistent cough, asthma, hypertension, heart disease, and gastrointestinal problems. Comorbid anxiety and depression were associated with an increase in the number of physical disorders and the degree of disability during the two-year follow-up, compared to anxiety or depression alone or the absence of anxiety or depression. Conclusion: Anxiety, depression, and particularly their comorbidity should be assessed in the elderly population considering their longitudinal effects on physical disorders and disability. Future study is required to determine whether interventions aimed at these disorders can mitigate their impacts.

Abstract

Objective: This study aimed to investigate the longitudinal effects of anxiety, depression, and their comorbidity on physical disorders and disability in an elderly Korean population. Methods: In total, 1,204 community-dwelling elders were evaluated at baseline, and of these 909 (75%) were re-assessed two years later. Anxiety and depression were identified at baseline using questions from the community version of the Geriatric Mental State diagnostic schedule (GMS-B3). Participants were assessed for functional disability and for 11 physical disorders both at baseline and at follow-up. Results: Anxiety alone was associated with the incidence of heart disease, depression alone with the incidence of asthma, and comorbid anxiety and depression with incidence of eyesight problem, persistent cough, asthma, hypertension, heart disease, and gastrointestinal problems. Comorbid anxiety and depression were associated with an increase in the number of physical disorders and the degree of disability during the two-year follow-up, compared to anxiety or depression alone or the absence of anxiety or depression. Conclusion: Anxiety, depression, and particularly their comorbidity should be assessed in the elderly population considering their longitudinal effects on physical disorders and disability. Future study is required to determine whether interventions aimed at these disorders can mitigate their impacts.

참고문헌 (45)

  1. Lenze EJ, "Comorbidity of depression and anxiety disorders in later life", Depress Anxiety, 14, pp.86~93 (2001)
  2. 강희주, "Comorbidity of Depression with Physical Disorders: Research and Clinical Implications", 전남의대학술지, 51(1), pp.8~18 (2015), 의과학연구소
  3. Schoevers RA, "Depression and generalized anxiety disorder : co-occurrence and longitudinal patterns in elderly patients", Am J Geriatr Psychiatry, 13, pp.31~39 (2005)
  4. Bhattacharya R, "Excess risk of chronicphysical conditions associated with depression and anxiety", BMC Psychiatry, 4, pp.10~ (2014)
  5. Patten SB, "Major depression as a risk factor for chronic disease incidence : longitudinal analyses in a general population cohort", Gen Hosp Psychiatry, 30, pp.407~413 (2008)
  6. Scott KM, "Depression-anxiety relationships with chronic physical conditions : results from the World Mental Health Surveys", J Affect Disord, 103, pp.113~120 (2007)
  7. Dall TM, "An aging population and growing disease burden will require a large and specialized health care workforce by 2025", Health Aff(Milwood), 32, pp.2013~2020 (2013)
  8. Choi NG, "Late-life depression and cardiovascular disease burden : examination of reciprocal relationship", Am J Geriatr Psychiatry, 22, pp.1522~1529 (2014)
  9. Brown JM, "Risk of coronary heart disease events over 15 years among older adults with depressive symptoms", Am J Geriatr Psychiatry, 19, pp.721~729 (2011)
  10. El-Gabalawy R, "A longitudinal examination of anxiety disorders and physical health conditions in a nationally representative sample of U.S. older adults", Exp Gerontol, 60, pp.46~56 (2014)
  11. Gallo JJ, "The epidemiology of common late-life mental disorders in the community : themes for the new century", Psychiatr Serv, 50, pp.1158~1166 (1999)
  12. Prina AM, "Co-occurrence of anxiety and depression amongst older adults in low-and middle-income countries : findings from the 10", 66 study, 2011, pp.41, 2047~2056
  13. Barry LC, "Longitudinal association between depressive symptoms and disability burden among older persons", J Gerontol A Biol Sci Med Sci, 64, pp.1325~1332 (2009)
  14. Cairney J, "Comorbid depression and anxiety in later life: patterns of association, subjective well-being, and impairment", Am J Geriatr Psychiatry, 16, pp.201~208 (2008)
  15. Braam AW, "Depression, subthreshold depression ad comorbid anxiety symptoms in older Europeans: results from the EURODEP concerted action", J Affect Disord, 155, pp.266~272 (2014)
  16. Kim JM, "Physical health and incident late life depression : modification by cytokine genes", Neurobiol Aging, 34, pp.356~ (2013)
  17. Copeland JR, "A computerized psychiatric diagnostic system and case nomenclature for elderly subjects : GMS and AGECAT", Psychol Med, 16, pp.89~99 (1986)
  18. Lyness JM, "The clinical significance of subsyndromal depression in older primary care patients", Am J Geriatr Psychiatry, 15, pp.214~223 (2007)
  19. Lindesay J, "The Guy’s", Age Concern Survey : physical health and psychiatric disorder in an urban elderly community, 1990, pp.5, 171~178
  20. Kim JM, "Physical health, depression and cognitive function as correlates of disability in an older Korean population", Int J Geriatr Psychiatry, 20, pp.160~167 (2005)
  21. World Health Organization, "International Classification of Functioning, Disability, and Health (ICF)", World Health Organization, ~ (2001)
  22. Epping-Jordan JA, "The WHODAS-II : leveling the playing field for all disorders", WHO Mental Health Bull, 6, pp.5~6 (2000)
  23. von Korff M, "Modified WHODAS-II provides valid measure of global disability but filter items increased skewness", J Clin Epidemiol, 61, pp.1132~1143 (2008)
  24. Sousa RM, "Measuring disability across cultures--the psychometric properties of the WHODAS II in older people from seven low- and middle-income countries. The 10", 66 Dementia Research Group population-based survey, 2010, pp.19, 1~17
  25. Chang KH, "Association between muscle power impairment and WHODAS 2.0 in older adults with physical disability in Taiwan", Disabil Rehabil, 37, pp.712~720 (2015)
  26. Vink D, "Risk factors for anxiety and depression in the elderly : a review", J Affect Disord, 106, pp.29~44 (2008)
  27. Prince M, "Dementia diagnosis in developing countries: a cross-cultural validation study", Lancet, 361, pp.909~917 (2003)
  28. Folstein MF, "“Mini-Mental State”. A practical method for grading the cognitive state of patients for the clinician", J Psychiatr Res, 12, pp.189~198 (1975)
  29. Bryant C, "The prevalence of anxiety in older adults : methodological issues and a review of the literature", J Affect Disord, 109, pp.233~250 (2008)
  30. Djernes JK, "Prevalence and predictors of depression in populations of elderly : a review", Acta Psychiatr Scand, 113, pp.372~387 (2006)
  31. Kvaal K, "Co-occurrence of anxiety and depressive disorders in a community sample of older people: results from the MRC CFAS (Medical Research Council Cognitive Function and Ageing Study)", Int J Geriatr Psychiatry, 23, pp.229~237 (2008)
  32. Meng L, "Depression increases the risk of hypertension incidence : a meta-analysis of prospective cohort studies", J Hypertens, 30, pp.842~851 (2012)
  33. Koloski NA, "The brain--gut pathway in functional gastrointestinal disorders is bidirectional : a 12-year prospective population-based study", Gut, 61, pp.1284~1290 (2012)
  34. Ananthakrishnan AN, "Association between depressive symptoms and incidence of Crohn’s disease and ulcerative colitis : results from the Nurses’ Health Study", Clin Gastroenterol Hepatol, 11, pp.57~62 (2013)
  35. Litcher-Kelly L, "Longitudinal study of the impact of psychological distress symptoms on new-onset upper gastrointestinal symptoms in World Trade Center responders", Psychosom Med, 76, pp.686~693 (2014)
  36. Carrière I, "A prospective study of the bi-directional association between vision loss and depression in the elderly", J Affect Disord, 151, pp.164~170 (2013)
  37. Bartels SJ, "Suicidal and death ideation in older primary care patients with depression and anxiety and at risk alcohol use", Am J Geriatr Psychiatry, 10, pp.417~427 (2002)
  38. Schneiderman N, "Stress and health : psychological behavioral and biological determinants", Annu Rev Clin Psychol, 1, pp.607~628 (2005)
  39. El-Gabalawy R, "Comorbid physical health conditions and anxiety disorders : a population-based exploration of prevalence and health outcomes among older adults", Gen Hosp Psychiatry, 33, pp.556~564 (2011)
  40. Kubzansky LD, "Prospective study of posttraumatic stress disorder symptoms and coronary heart disease in the Normative Aging Study", Arch Gen Psychiatry, 64, pp.109~116 (2007)
  41. Mehta KM, "Anxiety symptoms and decline in physical function over 5 years in the health, aging and body composition study", J Am Geriatr Soc, 55, pp.265~270 (2007)
  42. Gao YH, "The Relationship between depression and asthma: a meta-analysis of prospective studies", PLoS One, 10, pp.e0132424~ (2015)
  43. Barnett K, "Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study", Lancet, 380, pp.37~43 (2012)
  44. Kriegsman DM, "Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly. A study on the accuracy of patients’ self-reports and on determinants of inaccuracy", J Clin Epidemiol, 49, pp.1407~1417 (1996)
  45. Smith GS, "Translational research in late-life mood disorders : implications for future intervention and prevention research", Neuropsychopharmacology, 32, pp.1857~1875 (2007)

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