Evaluation of accuracies of genomic predictions for body conformation traits in Korean Holstein
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective: This study aimed to assess the genetic parameters and accuracy of genomic predictions for twenty-four linear body conformation traits and overall conformation scores in Korean Holstein dairy cows.Methods: A dataset of 2,206 Korean Holsteins was collected, and genotyping was performed using the Illumina Bovine 50K single nucleotide polymorphism (SNP) chip. The traits investigated included body traits (stature, height at front end, chest width, body depth, angularity, body condition score, and locomotion), rump traits (rump angle, rump width, and loin strength), feet and leg traits (rear leg set, rear leg rear view, foot angle, heel depth, and bone quality), udder traits (udder depth, udder texture, udder support, fore udder attachment, front teat placement, front teat length, rear udder height, rear udder width, and rear teat placement), and overall conformation score. Accuracy of genomic predictions was assessed using the single-trait animal model genomic best linear unbiased prediction method implemented in the ASReml-SA v4.2 software.Results: Heritability estimates ranged from 0.10 to 0.50 for body traits, 0.21 to 0.35 for rump traits, 0.13 to 0.29 for feet and leg traits, and 0.05 to 0.46 for udder traits. Rump traits exhibited the highest average heritability (0.29), while feet and leg traits had the lowest estimates (0.21). Accuracy of genomic predictions varied among the twenty-four linear body conformation traits, ranging from 0.26 to 0.49. The heritability and prediction accuracy of genomic estimated breeding value (GEBV) for the overall conformation score were 0.45 and 0.46, respectively. The GEBVs for body conformation traits in Korean Holstein cows had low accuracy, falling below the 50% threshold.Conclusion: The limited response to selection for body conformation traits in Korean Holsteins may be attributed to both the low heritability of these traits and the lower accuracy estimates for GEBVs. Further research is needed to enhance the accuracy of GEBVs and improve the selection response for these traits.
Abstract
Objective: This study aimed to assess the genetic parameters and accuracy of genomic predictions for twenty-four linear body conformation traits and overall conformation scores in Korean Holstein dairy cows. Methods: A dataset of 2,206 Korean Holsteins was collected, and genotyping was performed using the Illumina Bovine 50K single nucleotide polymorphism (SNP) chip. The traits investigated included body traits (stature, height at front end, chest width, body depth, angularity, body condition score, and locomotion), rump traits (rump angle, rump width, and loin strength), feet and leg traits (rear leg set, rear leg rear view, foot angle, heel depth, and bone quality), udder traits (udder depth, udder texture, udder support, fore udder attachment, front teat placement, front teat length, rear udder height, rear udder width, and rear teat placement), and overall conformation score. Accuracy of genomic predictions was assessed using the single-trait animal model genomic best linear unbiased prediction method implemented in the ASReml-SA v4.2 software. Results: Heritability estimates ranged from 0.10 to 0.50 for body traits, 0.21 to 0.35 for rump traits, 0.13 to 0.29 for feet and leg traits, and 0.05 to 0.46 for udder traits. Rump traits exhibited the highest average heritability (0.29), while feet and leg traits had the lowest estimates (0.21). Accuracy of genomic predictions varied among the twenty-four linear body conformation traits, ranging from 0.26 to 0.49. The heritability and prediction accuracy of genomic estimated breeding value (GEBV) for the overall conformation score were 0.45 and 0.46, respectively. The GEBVs for body conformation traits in Korean Holstein cows had low accuracy, falling below the 50% threshold. Conclusion: The limited response to selection for body conformation traits in Korean Holsteins may be attributed to both the low heritability of these traits and the lower accuracy estimates for GEBVs. Further research is needed to enhance the accuracy of GEBVs and improve the selection response for these traits.
참고문헌 (40)
- Wu X, "Genome wide association studies for body conformation traits in the Chinese Holstein cattle population", BMC Genomics, 14, pp.897~ (2013)[DOI]
- Stefani G, "Association of longevity with type traits, milk yield and udder health in Holstein cows", Livest Sci, 218, pp.1~7 (2018)[DOI]
- Abo-Ismail MK, "Genome-wide association studies and genomic prediction of breeding values for calving performance and body conformation traits in Holstein cattle", Genet Sel Evol, 49, pp.82~ (2017)[DOI]
- Pozveh ST, "Genetic analysis of reproduction traits and their relationship with conformation traits in Holstein cows", Livest Sci, 125, pp.84~87 (2009)[DOI]
- Gibson KD, "Genetic parameters for yield, fitness, and type traits in US Brown Swiss dairy cattle", J Dairy Sci, 101, pp.1251~1257 (2018)[DOI]
- Zink V, "Genetic parameters for female fertility, locomotion, body condition score, and linear type traits in Czech Holstein cattle", J Dairy Sci, 94, pp.5176~5182 (2011)[DOI]
- Perez-Cabal MA, "Genetic relationships between lifetime profit and type traits in Spanish Holstein cows", J Dairy Sci, 85, pp.3480~3491 (2002)[DOI]
- Vollema AR, "Genetic evaluation for longevity of Dutch dairy bulls", J Dairy Sci, 83, pp.2629~2639 (2000)[DOI]
- Goddard ME, "Genomic selection", J Anim Breed Genet, 124, pp.323~330 (2007)[DOI]
- Meuwissen T, "Genomic selection : a paradigm shift in animal breeding", Anim Front, 6, pp.6~14 (2016)[DOI]
- "Manual for type classification of cows" (2023)[URL]
- Cho C, "Genetic parameters for eighteen linear type traits in Holstein cattle", Ann Anim Resour Sci, 25, pp.89~96 (2014)[DOI]
- "Linear descriptive traits" (2023)[URL]
- Purcell S, "PLINK : a tool set for whole-genome association and population-based linkage analyses", Am J Hum Genet, 81, pp.559~575 (2007)[DOI]
- Yang J, "GCTA : a tool for genome-wide complex trait analysis", Am J Hum Genet, 88, pp.76~82 (2011)[DOI]
- VanRaden PM, "Efficient methods to compute genomic predictions", J Dairy Sci, 91, pp.4414~4423 (2008)[DOI]
- Meher PK, "Performance of Bayesian and BLUP alphabets for genomic prediction: analysis, comparison and results", Heredity (Edinb), 128, pp.519~530 (2022)[DOI]
- Badke YM, "Accuracy of estimation of genomic breeding values in pigs using lowdensity genotypes and imputation", G3(Bethesda), 4, pp.623~631 (2014)[DOI]
- Olasege BS, "Genetic parameter estimates for body conformation traits using composite index, principal component, and factor analysis", J Dairy Sci, 102, pp.5219~5229 (2019)[DOI]
- Campos RV, "Genetic parameters for type traits in Holstein cows in Brazil", Rev Bras Zootec, 41, pp.2150~2161 (2012)[DOI]
- Wasana N, "Genetic relationship of productive life, production and type traits of korean holsteins at early lactations", Asian-Australas J Anim Sci, 28, pp.1259~1265 (2015)[DOI]
- "National genetic evaluation forms provided by countries" (2012)[URL]
- Oliveira Junior GA, "Estimated genetic parameters for all genetically evaluated traits in Canadian Holsteins", J Dairy Sci, 104, pp.9002~9015 (2021)[DOI]
- Battagin M, "Genetic parameters for body condition score, locomotion, angularity, and production traits in Italian Holstein cattle", J Dairy Sci, 96, pp.5344~5351 (2013)[DOI]
- Van Dorp TE, "Genetics of locomotion", Livest Prod Sci, 90, pp.247~253 (2004)[DOI]
- Zavadilova L, "Genetic correlations between longevity and conformation traits in the Czech Holstein population", Czech J Anim Sci, 57, pp.125~136 (2012)[DOI]
- Petrini J, "Genetic parameters for milk fatty acids, milk yield and quality traits of a Holstein cattle population reared under tropical conditions", J Anim Breed Genet, 133, pp.384~395 (2016)[DOI]
- Utrera AR, "Heritability estimates for carcass traits of cattle : a review", Genet Mol Res, 3, pp.380~394 (2004)
- Pantelic V, "Variability and heritability of type traits of Holstein-Friesian bull dams", Biotechnol Anim Husb, 27, pp.305~313 (2011)[DOI]
- Sewalem A, "Analysis of the relationship between type traits and functional survival in Canadian Holsteins using a Weibull proportional hazards model", J Dairy Sci, 87, pp.3938~3946 (2004)[DOI]
- Kramer M, "Estimation of genetic parameters for novel functional traits in Brown Swiss cattle", J Dairy Sci, 96, pp.5954~5964 (2013)[DOI]
- Seykora AJ, "Heritabilities of teat traits and their relationships with milk yield, somatic cell count, and percent two-minute milk", J Dairy Sci, 68, pp.2670~2683 (1985)[DOI]
- Houle D, "Comparing evolvability and variability of quantitative traits", Genetics, 130, pp.195~204 (1992)[DOI]
- Getu A, "The role of conformational traits on dairy cattle production and their longevities", Open Access Libr J, 2, pp.e1342~ (2015)[DOI]
- Zhou L, "Factors affecting GEBV accuracy with single-step Bayesian models", Heredity(Edinb), 120, pp.100~109 (2018)[DOI]
- Haque MA, "Assessment of genomic breeding values and their accuracies for carcass traits in Jeju Black cattle using whole-genome SNP chip panels", J Anim Breed Genet, 140, pp.519~531 (2023)[DOI]
- Misztal I, "Experiences with a singlestep genome evaluation", Poult Sci, 92, pp.2530~2534 (2013)[DOI]
- Hayes BJ, "Invited review : Genomic selection in dairy cattle : progress and challenges", J Dairy Sci, 92, pp.433~443 (2009)[DOI]
- Song H, "Short communication : improving the accuracy of genomic prediction of body conformation traits in Chinese Holsteins using markers derived from high-density marker panels", J Dairy Sci, 101, pp.5250~5254 (2018)[DOI]