Initial Seizure Threshold in Brief-Pulse Bilateral Electroconvulsive Therapy in Patients with Schizophrenia or Schizoaffective Disorder
0
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Objective The present study aimed to report the initial seizure threshold (IST) of a brief-pulse bilateral electroconvulsive therapy (BPBL ECT) in Korean patients with schizophrenia/schizoaffective disorder and to identify IST predictors. Methods Among 67 patients who received ECT and diagnosed with schizophrenia/schizoaffective disorder based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, we included 56 patients who received 1-millisecond BP-BL ECT after anesthesia with sodium thiopental between March 2012 and June 2018. Demographic and clinical information was gathered from electronic medical records, and a multiple regression analysis was conducted to identify predictors of the IST. Results The mean age of the patients was 36.9±12.0 years and 30 (53.6%) patients were male. The mean and median IST were 105.9±54.5 and 96 millicoulombs (mC), respectively. The IST was predicted by age, gender, and dose (mg/kg) of sodium thiopental. Other physical and clinical variables were not associated with the IST. Conclusion The present study demonstrated that the IST of 1-ms BP-BL ECT following sodium thiopental anesthesia in Korean patients was comparable to those reported in previous literature. The IST was associated with age, gender, and dose of sodium thiopental.
Abstract
Objective The present study aimed to report the initial seizure threshold (IST) of a brief-pulse bilateral electroconvulsive therapy (BPBL ECT) in Korean patients with schizophrenia/schizoaffective disorder and to identify IST predictors. Methods Among 67 patients who received ECT and diagnosed with schizophrenia/schizoaffective disorder based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, we included 56 patients who received 1-millisecond BP-BL ECT after anesthesia with sodium thiopental between March 2012 and June 2018. Demographic and clinical information was gathered from electronic medical records, and a multiple regression analysis was conducted to identify predictors of the IST. Results The mean age of the patients was 36.9±12.0 years and 30 (53.6%) patients were male. The mean and median IST were 105.9±54.5 and 96 millicoulombs (mC), respectively. The IST was predicted by age, gender, and dose (mg/kg) of sodium thiopental. Other physical and clinical variables were not associated with the IST. Conclusion The present study demonstrated that the IST of 1-ms BP-BL ECT following sodium thiopental anesthesia in Korean patients was comparable to those reported in previous literature. The IST was associated with age, gender, and dose of sodium thiopental.
참고문헌 (56)
- Kellner CH, "ECT in treatment-resistant depression", Am J Psychiatry, 169, pp.1238~1244 (2012)
- Pompili M, "Indications for electroconvulsive treatment in schizophrenia : a systematic review", Schizophr Res, 146, pp.1~9 (2013)
- Sackeim H, "Seizure threshold in electroconvulsive therapy. Effects of sex, age, electrode placement, and number of treatments", Arch Gen Psychiatry, 44, pp.355~360 (1987)
- McCall WV, "Titrated moderately suprathreshold vs fixed high-dose right unilateral electroconvulsive therapy : acute antidepressant and cognitive effects", Arch Gen Psychiatry, 57, pp.438~444 (2000)
- Loo CK, "Recent advances in optimizing electroconvulsive therapy", Aust N Z J Psychiatry, 40, pp.632~638 (2006)
- Abrams R, "Electroconvulsive Therapy" (2002), Oxford University Press
- McClintock SM, "Multifactorial determinants of the neurocognitive effects of electroconvulsive therapy", J ECT, 30, pp.165~176 (2014)
- Tiller JW, "Seizure threshold determination for electroconvulsive therapy : stimulus dose titration versus age-based estimations", Aust N Z J Psychiatry, 40, pp.188~192 (2006)
- Ward WK, "A naturalistic comparison of two right unilateral electroconvulsive therapy dosing protocols : 2-3X seizure threshold versus fixed high-dose", Psychiatry Clin Neurosci, 60, pp.429~433 (2006)
- Petrides G, "Seizure threshold in a large sample : implications for stimulus dosing strategies in bilateral electroconvulsive therapy : a report from CORE", J ECT, 25, pp.232~237 (2009)
- Sackeim HA, "Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy", N Engl J Med, 328, pp.839~846 (1993)
- Enns M, "Electrical dose titration for electroconvulsive therapy : a comparison with dose prediction methods", Convuls Ther, 11, pp.86~93 (1995)
- Sackeim HA, "Stimulus intensity, seizure threshold, and seizure duration : impact on the efficacy and safety of electroconvulsive therapy", Psychiatr Clin North Am, 14, pp.803~843 (1991)
- McCall WV, "Convulsive threshold differences in right unilateral and bilateral ECT", Biol Psychiatry, 34, pp.606~611 (1993)
- Coffey CE, "Seizure threshold in electroconvulsive therapy: I. Initial seizure threshold", Biol Psychiatry, 37, pp.713~720 (1995)
- Boylan LS, "Determinants of seizure threshold in ECT : benzodiazepine use, anesthetic dosage, and other factors", J ECT, 16, pp.3~18 (2000)
- Bundy BD, "Influence of anesthetic drugs and concurrent psychiatric medication on seizure adequacy during electroconvulsive therapy", J Clin Psychiatry, 71, pp.775~777 (2010)
- van Waarde JA, "Clinical predictors of seizure threshold in electroconvulsive therapy : a prospective study", Eur Arch Psychiatry Clin Neurosci, 263, pp.167~175 (2013)
- Galvez V, "Predictors of seizure threshold in right unilateral ultrabrief electroconvulsive therapy : role of concomitant medications and anaesthesia used", Brain Stimul, 8, pp.486~492 (2015)
- Scott AI, "Initial seizure threshold in the clinical practice of bilateral electroconvulsive therapy in Edinburgh, Scotland", J ECT, 15, pp.118~124 (1999)
- Dawkins K, "Ethnicity and seizure threshold", Prog Neuropsychopharmacol Biol Psychiatry, 24, pp.1289~1298 (2000)
- Williams MD, "Outcome of electroconvulsive therapy by race in the Consortium for Research on Electroconvulsive Therapy multisite study", J ECT, 24, pp.117~121 (2008)
- Yasuda K, "Seizure threshold and the half-age method in bilateral electroconvulsive therapy in Japanese patients", Psychiatry Clin Neurosci, 69, pp.49~54 (2015)
- 지수혁, "Effects of Psychotropic Drugs on Seizure Threshold during Electroconvulsive Therapy", PSYCHIATRY INVESTIGATION, 14(5), pp.647~655 (2017), 대한신경정신의학회[DOI]
- Petrides G, "The"half-age"stimulation strategy for ECT dosing", Convuls Ther, 12, pp.138~146 (1996)
- Swartz CM, "Age-based seizure threshold determination", J ECT, 29, pp.18~20 (2013)
- Rosenman SJ, "Electroconvulsive therapy stimulus titration : not all it seems", Aust N Z J Psychiatry, 52, pp.410~414 (2018)
- Chanpattana W, "Seizure threshold rise during electroconvulsive therapy in schizophrenic patients", Psychiatry Res, 96, pp.31~40 (2000)
- Chung KF, "Initial seizure threshold of bilateral electroconvulsive therapy in Chinese", J ECT, 17, pp.254~258 (2001)
- Chung KF, "Stimulus dose titration for electroconvulsive therapy", Psychiatry Clin Neurosci, 55, pp.105~110 (2001)
- Lee MR, "Guidelines for the adequate initial electric stimuli in bilateral ECT using MECTA device", Korean J Psychopharmacol, 10, pp.138~142 (1999)
- Abrams R, "Stimulus titration and ECT dosing", J ECT, 18, pp.3~9 (2002)[DOI]
- Joo SW, "Effects of stimulus parameters on motor seizure duration in electroconvulsive therapy", Neuropsychiatr Dis Treat, 13, pp.1427~1434 (2017)
- Bersani G, "Seizure threshold variations in ECT-treated chronic patients with schizophrenia : a brief report", Riv Psichiatr, 49, pp.84~88 (2014)
- Pawelczyk T, "Effectiveness and clinical predictors of response to combined ECT and antipsychotic therapy in patients with treatment-resistant schizophrenia and dominant negative symptoms", Psychiatry Res, 220, pp.175~180 (2014)
- Lally J, "Augmentation of clozapine with electroconvulsive therapy in treatment resistant schizophrenia : A systematic review and meta-analysis", Schizophr Res, 171, pp.215~224 (2016)
- 김혜성, "Effectiveness of Electroconvulsive Therapy Augmentation on Clozapine-Resistant Schizophrenia", PSYCHIATRY INVESTIGATION, 14(1), pp.58~62 (2017), 대한신경정신의학회[DOI]
- Bueno CR, "Cardiovascular safety of the method of limits titration procedure for electroconvulsive therapy dosing : a retrospective study", Brain Stimul, 4, pp.43~45 (2011)
- Mizen L, "The cardiovascular safety of the empirical measurement of the seizure threshold in electroconvulsive therapy", BJPsych Bull, 39, pp.14~18 (2015)
- Coffey CE, "Seizure threshold in electroconvulsive therapy (ECT) II. The anticonvulsant effect of ECT", Biol Psychiatry, 37, pp.777~788 (1995)
- Rattehalli RD, "Measuring electroencephalographic seizure adequacy during electroconvulsive therapy : a comparison of 2 definitions", J ECT, 25, pp.243~245 (2009)
- "R: A Language and Environment for Statistical Computing" (2018)[URL]
- van Waarde JA, "Meta-analysis of initial seizure thresholds in electroconvulsive therapy", Eur Arch Psychiatry Clin Neurosci, 259, pp.467~474 (2009)
- Nitturkar AR, "Effect of age and anticonvulsants on seizure threshold during bilateral electroconvulsive therapy with brief-pulse stimulus : A chart-based analysis", Indian J Psychiatry, 58, pp.190~197 (2016)
- Galvez V, "Do benzodiazepines moderate the effectiveness of bitemporal electroconvulsive therapy in major depression?", J Affect Disord, 150, pp.686~690 (2013)
- Tang VM, "Should benzodiazepines and anticonvulsants be used during electroconvulsive therapy? : A case study and literature review", J ECT, 33, pp.237~242 (2017)
- Rakesh G, "Concomitant anticonvulsants with bitemporal electroconvulsive therapy : a randomized controlled trial with clinical and neurobiological application", J ECT, 33, pp.16~21 (2017)
- Hoyer C, "Impact of the anesthetic agents ketamine, etomidate, thiopental, and propofol on seizure parameters and seizure quality in electroconvulsive therapy : a retrospective study", Eur Arch Psychiatry Clin Neurosci, 264, pp.255~261 (2014)
- Kadiyala PK, "Anaesthesia for electroconvulsive therapy : an overview with an update on its role in potentiating electroconvulsive therapy", Indian J Anaesth, 61, pp.373~380 (2017)
- Zahavi GS, "Comparison of anesthetics in electroconvulsive therapy : an effective treatment with the use of propofol, etomidate, and thiopental", Neuropsychiatr Dis Treat, 10, pp.383~389 (2014)
- Anand S, "Anesthesia during electroconvulsive therapy : importance of dosage", J ECT, 26, pp.145~ (2010)
- "The ECT Handbook" (2013), RCPsych Publications
- Lemasson M, "Pertinence of titration and age-based dosing methods for Eelectroconvulsive therapy : an international retrospective multicenter study", J ECT, 34, pp.220~226 (2018)
- Wells DG, "ECT-induced asystole from a sub-convulsive shock", Anaesth Intensive Care, 16, pp.368~371 (1988)
- Bennett DM, "A comparison of ECT dosing methods using a clinical sample", J Affect Disord, 141, pp.222~226 (2012)
- Chung KF, "Determinants of seizure threshold of electroconvulsive therapy in Chinese", J ECT, 22, pp.100~102 (2006)
