Influence of Sensory Impairments on Incidence of Dementia in the Korean Population
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Objective Previous studies have shown the influence of visual and auditory sensory impairment on dementia incidence. In this study, we tested the hypothesis that the incidence of dementia will increase with visual and auditory impairments than with visual or auditory impairment.Methods Data from the Korea National Health Insurance Service database were used, including disease and medication codes from 2009 to 2018, and the 2011 national health check-up results. Participants were grouped based on their sensory abilities: normal, visual impairment, auditory impairment, and both visual and auditory impairments (dual sensory impairment). To compare the incidence of dementia, hazard ratios were calculated for each group, with reference to the normal sensory (NS) group. Sensitivity analyses were performed comparing dementia incidence from 2014 to 2018, excluding the onset of the disease in 2012 and 2013.Results We identified 8,289 cases of dementia during the seven-year follow-up. In the multiple Cox regression analysis, adjusted for sex, social economic status, age, comorbidities, smoking, alcohol consumption, and activity level, the auditory impairment (hazard ratio= 1.1908) and visual impairment (hazard ratio=1.3553) groups showed a significantly higher dementia incidence than the NS group. Dual sensory impairment (hazard ratio=1.5267) showed the highest incidence. The sensitivity analysis yielded similar results.Conclusion Visual and auditory impairments are associated with an increased risk of dementia, particularly in individuals with dual sensory impairment. Hence, visual and auditory impairments might have increased the risk of dementia through independent pathological processes. Therefore, preventing and correcting sensory impairment is necessary to reduce the risk of dementia.
Abstract
Objective Previous studies have shown the influence of visual and auditory sensory impairment on dementia incidence. In this study, we tested the hypothesis that the incidence of dementia will increase with visual and auditory impairments than with visual or auditory impairment.Methods Data from the Korea National Health Insurance Service database were used, including disease and medication codes from 2009 to 2018, and the 2011 national health check-up results. Participants were grouped based on their sensory abilities: normal, visual impairment, auditory impairment, and both visual and auditory impairments (dual sensory impairment). To compare the incidence of dementia, hazard ratios were calculated for each group, with reference to the normal sensory (NS) group. Sensitivity analyses were performed comparing dementia incidence from 2014 to 2018, excluding the onset of the disease in 2012 and 2013.Results We identified 8,289 cases of dementia during the seven-year follow-up. In the multiple Cox regression analysis, adjusted for sex, social economic status, age, comorbidities, smoking, alcohol consumption, and activity level, the auditory impairment (hazard ratio= 1.1908) and visual impairment (hazard ratio=1.3553) groups showed a significantly higher dementia incidence than the NS group. Dual sensory impairment (hazard ratio=1.5267) showed the highest incidence. The sensitivity analysis yielded similar results.Conclusion Visual and auditory impairments are associated with an increased risk of dementia, particularly in individuals with dual sensory impairment. Hence, visual and auditory impairments might have increased the risk of dementia through independent pathological processes. Therefore, preventing and correcting sensory impairment is necessary to reduce the risk of dementia.
참고문헌 (29)
- GBD 2019 Collaborators. Global mortality from dementia, "application of a new method and results from the Global Burden of Disease Study 2019", Alzheimers Dement(N Y), 7, pp.e12200~ (2021)
- Livingston G, "Dementia prevention, intervention, and care : 2020 report of the Lancet Commission", Lancet, 396, pp.413~446 (2020)
- Davies HR, "Hearing impairment and incident dementia : findings from the English longitudinal study of ageing", J Am Geriatr Soc, 65, pp.2074~2081 (2017)
- Lin FR, "Hearing loss and cognitive decline in older adults", JAMA Intern Med, 173, pp.293~299 (2013)
- Ward ME, "Reduced contrast sensitivity among older women is associated with increased risk of cognitive impairment", Ann Neurol, 83, pp.730~738 (2018)
- Davies-Kershaw HR, "Vision impairment and risk of dementia : findings from the English longitudinal study of ageing", J Am Geriatr Soc, 66, pp.1823~1829 (2018)
- Hwang PH, "Dual sensory impairment in older adults and risk of dementia from the GEM Study", Alzheimers Dement(Amst), 12, pp.e12054~ (2020)
- Kuo PL, "Prevalence of concurrent functional vision and hearing impairment and association with dementia in community-dwelling medicare beneficiaries", JAMA Netw Open, 4, pp.e211558~ (2021)
- Maruta M, "Impact of sensory impairments on dementia incidence and symptoms among Japanese older adults", Psychogeriatrics, 20, pp.262~270 (2020)
- Byeon G, "Dual sensory impairment and cognitive impairment in the Korean longitudinal elderly cohort", Neurology, 96, pp.e2284~e2295 (2021)
- Kim SY, "Hearing impairment and the risk of neurodegenerative dementia : a longitudinal follow-up study using a national sample cohort", Sci Rep, 8, pp.15266~ (2018)
- Paik JS, "Low vision and the risk of dementia : a nationwide population-based cohort study", Sci Rep, 10, pp.9109~ (2020)
- Stein JD, "Use of health care claims data to study patients with ophthalmologic conditions", Ophthalmology, 121, pp.1134~1141 (2014)
- Heine C, "Sensory loss in China : prevalence, use of aids, and impacts on social participation", Front Public Health, 7, pp.5~ (2019)
- Kim S, "Age-related hearing loss in the Korea National Health and Nutrition Examination Survey", PLoS one, 15, pp.e0243001~ (2020)
- 김응수, "2017년도 국민건강영양조사를 바탕으로 한 저시력 유병률 조사", 대한안과학회지, 61(4), pp.407~411 (2020), 대한안과학회
- 경대성, "Understanding and Utilizing Claim Data from the Korean National Health Insurance Service (NHIS) and Health Insurance Review & Assessment (HIRA) Database for Research", 지질·동맥경화학회지, 11(2), pp.103~110 (2022), 한국지질동맥경화학회[DOI]
- Shin DW, "Korean National Health Insurance Database", JAMA Intern Med, 176, pp.138~ (2016)
- Bowling CB, "Association of sustained blood pressure control with multimorbidity progression among older adults", J Am Geriatr Soc, 68, pp.2059~2066 (2020)
- Azzam D, "Snellen Chart" (2022), StatPearls Publishing
- Ng TP, "Age-dependent relationships between body mass index and mortality : Singapore longitudinal ageing study", PLoS one, 12, pp.e0180818~ (2017)
- Walker AM, "Proportion of disease attributable to the combined effect of two factors", Int J Epidemiol, 10, pp.81~85 (1981)
- Roberts KL, "Perception and cognition in the ageing brain : a brief review of the short-and long-term links between perceptual and cognitive decline", Front Aging Neurosci, 8, pp.39~ (2016)
- Shargorodsky J, "A prospective study of cardiovascular risk factors and incident hearing loss in men", Laryngoscope, 120, pp.1887~1891 (2010)
- Knopman D, "Cardiovascular risk factors and cognitive decline in middle-aged adults", Neurology, 56, pp.42~48 (2001)
- ZwislockiJ, "On the effect of practice and motivation on the threshold of audibility", J Acoust Soc Am, 30, pp.254~262 (1958)
- Rabbitt P, "Mild hearing loss can cause apparent memory failures which increase with age and reduce with IQ", Acta Otolaryngol Suppl, 111(Suppl 476), pp.167~176 (1991)
- Galvin JE, "Practical guidelines for the recognition and diagnosis of dementia", J Am Board Fam Med, 25, pp.367~382 (2012)
- Lin FR, "Association of hearing impairment with brain volume changes in older adults", Neuroimage, 90, pp.84~92 (2014)