Abdominal Obesity Increases the Risk for Depression by Sex: A Nationwide Cohort Study in South Korea
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Objective Previous studies have investigated obesity and appetite changes in patients with depression, which consisted of a small age range of adults and used body mass index rather than abdominal obesity. The objective of this study is to examine the relationship between abdominal obesity and the risk of depression by sex and age groups.Methods This study utilized the National Health Insurance Sharing Service (NHISS) database of South Korea, which includes those over 20 years old and who had undergone a health examination in 2009 and their claims data between 2009 and 2018. The diagnosis of depressive episodes was based on the International Statistical Classification of Disease and Related Health Problems 10th revision. Abdominal obesity was measured by waist circumference (WC) and was divided into six levels (cm). Cox proportional-hazard regression analyses were conducted to examine the relationship between abdominal obesity and the risk of depression by sex and age groups.Results Among 9,041,751 participants, 1,376,279 were diagnosed with depression. Those with higher WC (90 cm or higher for males, 85 cm or higher for females) showed an increased risk for depression in both sexes (hazard ratio [HR]=1.09, 95% confidence interval [CI]: 1.07–1.11 for males, HR=1.03, 95% CI: 1.02–1.05 for females). Underweight males (WC<80 cm) also showed an increased risk for depression (HR=1.05, 95% CI: 1.04–1.05).Conclusion It has been found that higher WC was associated with increased risks of depression in both sexes. Although underweight males showed an elevated risk of depression, a healthy weight is associated with fewer depression symptoms.
Abstract
Objective Previous studies have investigated obesity and appetite changes in patients with depression, which consisted of a small age range of adults and used body mass index rather than abdominal obesity. The objective of this study is to examine the relationship between abdominal obesity and the risk of depression by sex and age groups.Methods This study utilized the National Health Insurance Sharing Service (NHISS) database of South Korea, which includes those over 20 years old and who had undergone a health examination in 2009 and their claims data between 2009 and 2018. The diagnosis of depressive episodes was based on the International Statistical Classification of Disease and Related Health Problems 10th revision. Abdominal obesity was measured by waist circumference (WC) and was divided into six levels (cm). Cox proportional-hazard regression analyses were conducted to examine the relationship between abdominal obesity and the risk of depression by sex and age groups.Results Among 9,041,751 participants, 1,376,279 were diagnosed with depression. Those with higher WC (90 cm or higher for males, 85 cm or higher for females) showed an increased risk for depression in both sexes (hazard ratio [HR]=1.09, 95% confidence interval [CI]: 1.07–1.11 for males, HR=1.03, 95% CI: 1.02–1.05 for females). Underweight males (WC<80 cm) also showed an increased risk for depression (HR=1.05, 95% CI: 1.04–1.05).Conclusion It has been found that higher WC was associated with increased risks of depression in both sexes. Although underweight males showed an elevated risk of depression, a healthy weight is associated with fewer depression symptoms.
참고문헌 (26)
- Xu Q, "The relationship between abdominal obesity and depression in the general population : a systematic review and meta-analysis", Obes Res Clin Pract, 5, pp.e267~e278 (2011)
- Yim G, "The"jolly fat"effect in middle-aged Korean women", J Womens Health(Larchmt), 26, pp.1236~1243 (2017)
- Zhang D, "Effectiveness of a resilience-targeted intervention based on"I have, I am, I can"strategy on nursing home older adults’ suicidal ideation : a randomized controlled trial", J Affect Disord, 308, pp.172~180 (2022)
- Yu M, ""Jolly fat"or"sad fat" : a systematic review and meta-analysis of the association between obesity and depression among community-dwelling older adults", Aging Ment Health, 26, pp.13~25 (2022)
- Zhang L, "Relationship between body mass index and depressive symptoms : the"fat and jolly"hypothesis for the middle-aged and elderly in China", BMC Public Health, 16, pp.1201~ (2016)
- Luo H, "Obesity and the onset of depressive symptoms among middle-aged and older adults in China : evidence from the CHARLS", BMC Public Health, 18, pp.909~ (2018)
- Yoon DH, "The relationship between obesity and depression in Korean women", Korean J Psychosom Med, 15, pp.51~55 (2007)
- Jung SJ, "Association between body size, weight change and depression : systematic review and meta-analysis", Br J Psychiatry, 211, pp.14~21 (2017)
- Hong SM, "Relationship between obesity and depression in Korean adults: Korea national health and nutrition examination survey 2014", Medicine(Baltimore), 96, pp.e9478~ (2017)
- Paley CA, "Abdominal obesity and metabolic syndrome : exercise as medicine", BMC Sports Sci Med Rehabil, 10, pp.7~ (2018)
- Choi D, "Impact of discrepancies in general and abdominal obesity on major adverse cardiac events", J Am Heart Assoc, 8, pp.e013471~ (2019)
- Wiltink J, "Associations between depression and different measures of obesity(BMI, WC, WHtR, WHR)", BMC Psychiatry, 13, pp.223~ (2013)
- Shelton RC, "Eating ourselves to death(and despair) : the contribution of adiposity and inflammation to depression", Prog Neurobiol, 91, pp.275~299 (2010)
- Ameye H, "Obesity, income and gender : the changing global relationship", Glob Food Secur, 23, pp.267~281 (2019)
- Parker G, "Gender differences in depression", Int Rev Psychiatry, 22, pp.429~436 (2010)
- Lee J, "Cohort profile: the national health insurance service-national sample cohort (NHIS-NSC), South Korea", Int J Epidemiol, 46, pp.e15~ (2017)
- Shin DW, "National general health screening program in Korea : history, current status, and future direction", Precis Future Med, 6, pp.9~31 (2022)
- Seong SC, "Data resource profile : the national health information database of the national health insurance service in South Korea", Int J Epidemiol, 46, pp.799~800 (2017)
- Lee OG, "The cutoff value of waist circumference for predicting metabolic risks in pre-and post-menopausal Korean women : analysis of 2010 Korean national health and nutrition examination survey data", Korean J Fam Med, 34, pp.307~318 (2013)
- Hyeon JH, "Relationship between bone mineral density and alcohol consumption in Korean men : the fourth Korea national health and nutrition examination survey(KNHANES), 2008-2009", Asia Pac J Clin Nutr, 25, pp.308~315 (2016)
- Wellman JD, "Sex differences in the relationships among weight stigma, depression, and binge eating", Appetite, 133, pp.166~173 (2019)
- Frederick DA, "Desiring the muscular ideal : men’s body satisfaction in the United States, Ukraine, and Ghana", Psychol Men Masc, 8, pp.103~117 (2007)
- Silva D, "Depression, anthropometric parameters, and body image in adults: a systematic review", Rev Assoc Med Bras (1992), 65, pp.731~738 (2019)
- Zhang L, "Relationship between adiposity parameters and cognition: the “fat and jolly” hypothesis in middle-aged and elderly people in China", Medicine(Baltimore), 98, pp.e14747~ (2019)
- Walls HL, "Comparing trends in BMI and waist circumference", Obesity(Silver Spring), 19, pp.216~219 (2011)
- Milaneschi Y, "Depression and obesity : evidence of shared biological mechanisms", Mol Psychiatry, 24, pp.18~33 (2019)