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전신적 경련 후 발생한 횡문근융해증에 의해 초래된 급성신부전 1례

A Case of Acute Renal Failure due to Rhabdomyolysis Induced by Convulsion

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참고문헌

주제분류소아과학

초록

저자들은 핍뇨를 주소로 내원한 12세 남아에서 임상 소견 및 검사 소견 상 전신적 강직성 경련으로 유발된 횡문근융해증에 의해 초래된 급성신부전으로 진단하고 충분한 수액공급, 소변의 알칼리화, 이뇨제 투여와 함께 항경련제의 사용으로 경련을 조절함으로써 급성신부전이 호전된 1례를 경험하였기에 보고하는 바이다.

Abstract

Rhabdomyolysis is a syndrome resulting from skeletal muscle injury with release of muscle cell contents into the plasma. It has been reported as a cause of acute renal failure(ARF), and often associated with alcohol abuse, muscle compression, infections, and generalized seizure. Rhabdomyolysis-induced ARF is rare in children. We experienced a case of rhabdomyolysis-induced ARF in a 12-year-old boy who presented with azotemia and oliguria secondary to convulsion. After the control of convulsion by antiepileptic drugs, the daily urine output gradually increased and systemic features recovered with appropriate hydration and alkalinization.

참고문헌 (13)

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  7. Jung YS, "Two childhood cases of heat stroke with rhabdomyolysis and multiorgan failure", 41, pp.568~73 (1998)
  8. Chae DW, "The clinical features of acute renal failure accompanying rhabdomyolysis", 7, pp.153~60 (1988)
  9. Brumback RA, "Rhabdomyolysis in childhood:A primer on normal muscle function and selected metabolic myopathies characterized by disordered energy production", 39, pp.821~58 (1992)
  10. Zager RA, "Rhabdomyolysis and myohemoglobinuric acute renal failure", 49, pp.314~26 (1996)
  11. Singh D, "Rhabdomyolysis", 27, pp.39~48 (2005)
  12. Oken DE, "Modern concepts of the role of nephrotoxic agents in the pathogenesis of acute renal faulure", 7, pp.219~47 (1972)
  13. Ron D, "Prevention of acute renal failure in traumatic rhabdomyolysis", 144, pp.277~80 (1984)

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