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Prevention of Recurrent FSGS with Cyclosporine and Plasmapheresis Prior to Renal Transplantation

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초록

We report on two children with a high risk of recurrent focal segmental glomerulosclerosis (FSGS) after renal transplantation that could be effectively prevented by prophylactic administration of cyclosporine combined with preemptive plasmapheresis prior to renal transplantation.

Abstract

We report on two children with a high risk of recurrent focal segmental glomerulosclerosis (FSGS) after renal transplantation that could be effectively prevented by prophylactic administration of cyclosporine combined with preemptive plasmapheresis prior to renal transplantation.

참고문헌 (15)

  1. Fine RN, "Recurrence of nephrotic syndrome", focal segmental glomerulosclerosis following renal transplantation in children, 2007, pp.22, 496~502
  2. Greenstein SM, "Plasmapheresis treatment for recurrent focal sclerosis in pediatric renal allografts", Pediatr Nephrol, 14, pp.1061~1065 (2000)
  3. Cochat P, "Recurrent nephrotic syndrome after transplantation: early treatment with plasmapheresis and cyclophosphamide", Pediatr Nephrol, 7, pp.50~54 (1993)
  4. Gohh RY, "Preemptive plasmapheresis and recurrence of FSGS in high-risk renal transplant recipients", Am J Transplant, 5, pp.2907~2912 (2005)
  5. Ohta T, "Effect of pre- and postoperative plasmapheresis on posttransplant recurrence of focal segmental glomerulosclerosis in children", 71, pp.628~633 (2001)
  6. Salomon R, "Intravenous cyclosporine therapy in recurrent nephrotic syndrome after renal transplantation in children", Transplantation, 75, pp.810~814
  7. Raafat RH, "High-dose oral cyclosporin therapy for recurrent focal segmental glomerulosclerosis in children", Am J Kidney Dis, 44, pp.50~56 (2004)
  8. Stephanian E, "Recurrence of disease in patients retransplanted for focal segmental glomerulosclerosis", Transplantation, 53, pp.755~757 (1992)
  9. Kim EM, "Recurrence of steroid-resistant nephrotic syndrome in kidney transplants is associated with increased acute renal failure and acute rejection", Kidney Int, 45, pp.1440~1445 (1994)
  10. Savin VJ, "Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis", 334, pp.878~883 (1996)
  11. Dantal J, "Recurrent nephrotic syndrome following renal transplantation in patients with focal glomerulosclerosis. A one-center study of plasma exchange effects", Transplantation, 52, pp.827~831 (1991)
  12. Artero ML, "Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis", Am J Kidney Dis, 23, pp.574~581 (1994)
  13. Rianthavorn P, "A coherent approach to recurrent focal segmental glomerulosclerosis in children? The effects of high dose cyclosporine and pretransplant plasmapheresis", Pediatr Transplant, (6), pp.48~ (2005)
  14. Sharma R, "Cyclosporine protects glomeruli from FSGS factor via an increase in glomerular cAMP", Transplantation, 62, pp.1916~1920 (1996)
  15. Hariharan S, "Recurrent and de novo diseases after renal transplantation", Semin Dial, 13, pp.195~199 (2000)

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