A Case of Severe Influenza Infection in a Child with Nephrotic Syndrome on Steroid Therapy
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Infection is the most important cause of death in children with nephrotic syndrome. Influenza viral infections can be fatal for these children, given the annual outbreak of this virus, with the mortality rate being similar to that of respiratory syncytial virus in healthy children. Pneumonia is recognized as the most important complication of influenza infections, as it is associated with high death rates. However, the influenza vaccine, as well as antiviral agents, can be used for prevention and treatment. Therefore, aggressive management with influenza vaccination and antiviral agents will lower the overall mortality rate in children with nephrotic syndrome. Here we report the case of a 7-year-old boy with nephrotic syndrome and influenza A virus (H1N1) pneumonia.
Abstract
Infection is the most important cause of death in children with nephrotic syndrome. Influenza viral infections can be fatal for these children, given the annual outbreak of this virus, with the mortality rate being similar to that of respiratory syncytial virus in healthy children. Pneumonia is recognized as the most important complication of influenza infections, as it is associated with high death rates. However, the influenza vaccine, as well as antiviral agents, can be used for prevention and treatment. Therefore, aggressive management with influenza vaccination and antiviral agents will lower the overall mortality rate in children with nephrotic syndrome. Here we report the case of a 7-year-old boy with nephrotic syndrome and influenza A virus (H1N1) pneumonia.
참고문헌 (11)
- Giangiacomo J, "Serum immunoglobulins in the nephrotic syndrome. A possible cause of minimal-change nephrotic syndrome", N Engl J Med, 293, pp.8~ (1975)
- Spika JS, "Serum antibody response to pneumococcal vaccine in children with nephrotic syndrome", Pediatrics, 69, pp.219~ (1982)
- Anderson DC, "Assessment of serum factor B, serum opsonins, granulocyte chemotaxis, and infection in nephrotic syndrome of children", J Infect Dis, 140, pp.1~ (1979)
- 박세진, "Complications of nephrotic syndrome", Korean Journal of Pediatrics, 54(8), pp.322~328 (2011), 대한소아과학회
- Eddy AA, "Nephrotic syndrome in childhood", Lancet, 362, pp.629~639 (2003)
- Fleming DM, "Mortality in children from influenza and respiratory syncytial virus", J Epidemiol Community Health, 59, pp.586~590 (2005)
- "Update: novel influenza A (H1N1) virus infections - worldwide, May 6, 2009" (2009)[URL]
- Dawood FS, "Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modeling study", Lancet Infect Dis, 12, pp.687~695 (2012)
- "Pandemic (H1N1) 2009 - update 100" (2010)[URL]
- Gómez-Gómez A, "Severe pneumonia associated with pandemic (H1N1) 2009 outbreak", Emerg Infect Dis, 16, pp.27~34 (2010)
- Marion, DW, "Glucocorticoid effects on the immune system", UpToDate, ~ (2014)