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여성 노인의 대퇴 골밀도 감소에 따른 대사증후군과 체력 비교

Comparison of Metabolic Risk Factors and Physical Fitness according to Femur Osteoporotic Status in Elderly Women

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PURPOSE: This study was to compare metabolic risk factors and physical fitness according to femur bone mineral density (BMD) status in elderly women. METHODS: A total of 300 female participants aged 73.5±6.8 years were voluntarily recruited from local community centers. Whole body composition including body weight, body mass index (BMI), waist circumference, percent body fat, and bone mineral density, was determined using dual-energy X-ray absorptiometry. Metabolic risk factors, such as resting blood pressures, fasting glucose, and lipids, were assessed in fasting blood. Analysis of covariance (ANCOVA) followed by LSD post-hoc test, if necessary, was applied to determine significant differences in dependent variables among normal, osteopenia, and osteoporosis groups. Multivariate linear regression was used to determine significant determinants of osteoporotic status. RESULTS: ANCOVA showed significant differences in upper body strength (p<.001), upper and lower body flexibility (p=.024 & .048, respectively), and appendicular skeletal muscle mass (ASM) (p<.001) among the osteoporotic status-based subgroups; the normal and osteopenia groups had significantly higher means in upper strength (p<.05) upper and lower strength (p<.05), and ASM (p<.05) than the osteoporosis group. Multivariate linear regression analyses revealed that age (p<.001), upper body strength (p=.035), and BMI (p=.012) were independent predictors of osteoporotic status. CONCLUSIONS: Findings of this study suggest that muscular strength and BMI in conjunction with age were important factors in determining individual variability of bone health status in this study population, implying the importance of strength exercise and a healthy body weight against loss of bone density associated with aging.

Abstract

PURPOSE: This study was to compare metabolic risk factors and physical fitness according to femur bone mineral density (BMD) status in elderly women. METHODS: A total of 300 female participants aged 73.5±6.8 years were voluntarily recruited from local community centers. Whole body composition including body weight, body mass index (BMI), waist circumference, percent body fat, and bone mineral density, was determined using dual-energy X-ray absorptiometry. Metabolic risk factors, such as resting blood pressures, fasting glucose, and lipids, were assessed in fasting blood. Analysis of covariance (ANCOVA) followed by LSD post-hoc test, if necessary, was applied to determine significant differences in dependent variables among normal, osteopenia, and osteoporosis groups. Multivariate linear regression was used to determine significant determinants of osteoporotic status. RESULTS: ANCOVA showed significant differences in upper body strength (p<.001), upper and lower body flexibility (p=.024 & .048, respectively), and appendicular skeletal muscle mass (ASM) (p<.001) among the osteoporotic status-based subgroups; the normal and osteopenia groups had significantly higher means in upper strength (p<.05) upper and lower strength (p<.05), and ASM (p<.05) than the osteoporosis group. Multivariate linear regression analyses revealed that age (p<.001), upper body strength (p=.035), and BMI (p=.012) were independent predictors of osteoporotic status. CONCLUSIONS: Findings of this study suggest that muscular strength and BMI in conjunction with age were important factors in determining individual variability of bone health status in this study population, implying the importance of strength exercise and a healthy body weight against loss of bone density associated with aging.

참고문헌 (30)

  1. "NIH Consensus development panel on osteoporosis prevention, diagnosis, and therapy", JAMA, 285(6), pp.785~795 (2001)
  2. Looker AC, "Prevalence of low femoral bone density in older U.S. women from NHANES III", Journal of Bone and Mineral Research, 10(5), pp.796~802 (1995)
  3. 박은정, "Prevalence of Osteoporosis in the Korean Population Based on Korea National Health and Nutrition Examination Survey (KNHANES), 2008--2011", Yonsei Medical Journal, 55(4), pp.1049~1057 (2014), 연세대학교의과대학[DOI]
  4. De Laet C, "Body mass index as a predictor of fracture risk : a meta-analysis", Osteoporosis International, 16(11), pp.1330~1338 (2005)
  5. Cauley JA, "Estrogen and bone health in men and women", Steroids, 99, pp.11~15 (2015)
  6. Jennifer S. Walsh, "Obesity, Type 2 Diabetes and Bone in Adults", Calcified Tissue International, 100(5), pp.528~535 (2017), Springer Nature[DOI]
  7. Shan PF, "Bone mineral density and its relationship with body mass index in postmenopausal women with type 2 diabetes mellitus in mainland China", Journal of Bone and Mineral Metabolism, 27(2), pp.190~197 (2009)
  8. Lee I, "Body fat and physical activity modulate the association between sarcopenia and osteoporosis in elderly Korean women", Journal of Sports Science and Medicine, 15(3), pp.477~482 (2016)
  9. Bauer UE, "Prevention of chronic disease in the 21st century : elimination of the leading preventable causes of premature death and disability in the USA", Lancet, 384(9937), pp.45~52 (2014)
  10. Fougère B, "Chronic Inflammation: Accelerator of biological aging", The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, pp.pii:glw24~ (2016)
  11. Yamaguchi T, "Plasma lipids and osteoporosis in postmenopausal women", Endocrine Journal, 49(2), pp.211~217 (2002)
  12. Abbasi M, "Relationship between metabolic syndrome and its components with bone densitometry in postmenopausal women", Diabetes & Metabolic Syndrome (2016)
  13. Nguyen TV, "Bone loss, physical activity, and weight change in elderly women : the dubbo osteoporosis epidemiology study", Journal of Bone and Mineral Research, 13(9), pp.1458~1467 (1998)
  14. National Osteoporosis Foundation, "Clinician’s guide to prevention and treatment of osteoporosis" (2013), National Osteoporosis Foundation
  15. Gómez-Cabello A, "Effects of training on bone mass in older adults : A systematic review", Sports Medicine, 42(4), pp.301~325 (2012)
  16. DeFina LF, "High cardiorespiratory fitness is associated with reduced risk of low bone density in postmenopausal women", Journal of Women’s Health(Larchmt), 25(10), pp.1073~1080 (2016)
  17. Rikli RE, "Senior fitness test manual" (2000), Human Kinetics
  18. Grundy SM, "Diagnosis and management of the metabolic syndrome : an american heart association", national heart, lung, and blood institue scientific statement, 2005, pp.112(17), 2735~2752
  19. Korean Society for the Study of Obesity, "Management of obesity", Korean Society for the Study of Obesity, pp.17~21 (2012), Korean Society for the Study of Obesity
  20. Rachner TD, "Osteoporosis : now and the future", Lancet, 377(9773), pp.1276~1287 (2011)
  21. Cappola AR, "Osteoporosis therapy in postmenopausal women with high risk of fracture", JAMA, 316(7), pp.715~716 (2016)
  22. Tintut Y, "Effects of bioactive lipids and lipoproteins on bone", Trends in Endocrinology and Metabolism, 25(2), pp.53~59 (2014)
  23. Zhou L, "Bone mass loss is associated with systolic blood pressure in postmenopausal women with type 2diabetes in Tibet: a retrospective cross-sectional study", Osteoporos International (2017)
  24. Cakmak HA, "The relationships between blood pressure, blood glucose, and bone mineral density in postmenopausal Turkish women", Journal of Therapeutics and Clinical Risk Management, 11, pp.1641~1648 (2015)
  25. Moran LJ, "Sex hormone binding globulin, but not testosterone, is associated with the metabolic syndrome in overweight and obese women with polycystic ovary syndrome", Journal of Endocrinological Investigation, 36(11), pp.1004~1010 (2013)
  26. Bredella MA, "Vertebral bone marrow fat is positively associated with visceral fat and inversely associated with IGF-1 in obese women", Obesity (Silver Spring), 19(1), pp.49~53 (2011)
  27. Kirchengast S1, "Protective effect of moderate overweight on bone density of the hip joint in elderly and old Austrians", Anthropologischer Anzeiger, 60(2), pp.187~197 (2002)
  28. Iki M, "Trunk muscle strength is a strong predictor of bone loss in postmenopausal women", Clinical Orthopaedics and Related Research, 443, pp.66~72 (2006)
  29. Iki M, "Greater trunk muscle torque reduces postmenopausal bone loss at the spine independently of age, body size, and vitamin D receptor genotype in Japanese women", Calcified Tissue International, 71(4), pp.300~307 (2002)
  30. Lu YH, "Twelve-minute daily yoga regimen reverses osteoporotic bone loss", Topics in Geriatric Rehabilitation, 32(2), pp.81~87 (2016)

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