Gastrointestinal cancer organoids—applications in basic and translational cancer research

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참고문헌 (88)

1. Bray, F., "Global cancer statistics 2018 : GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries", Ca. Cancer J. Clin, 68, pp.394~424 (2018)
2. Caponigro, G., "Advances in the preclinical testing of cancer therapeutic hypotheses", Nat. Rev. Drug Discov, 10, pp.179~187 (2011)
3. Huch, M., "Modeling mouse and human development using organoid cultures", Development, 142, pp.3113~3125 (2015)
4. Shamir, E. R., "Three-dimensional organotypic culture : experimental models of mammalian biology and disease", Nat. Rev. Mol. Cell Biol, 15, pp.647~664 (2014)
5. Sato, T., "Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche", Nature, 459, pp.262~265 (2009)
6. de Lau, W., "Lgr5 homologues associate with Wnt receptors and mediate Rspondin signalling", Nature, 476, pp.293~297 (2011)
7. Carmon, K. S., "R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt", β-catenin signaling, 2011, pp.108, 11452~11457
8. Sato, T., "Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett’s epithelium", Gastroenterology, 141, pp.1762~1772 (2011)
9. Boj, S. F., "Organoid models of human and mouse ductal pancreatic cancer", Cell, 160, pp.324~338 (2015)
10. Huch, M., "Long-term culture of genome-stable bipotent stem", Cells Adult Hum. Liver. Cell, 160, pp.299~312 (2015)
11. Bartfeld, S., "In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection", Gastroenterology, 148, pp.126~136 (2015)
12. Stange, D. E., "Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium", Cell, 155, pp.357~368 (2013)
13. Barker, N., "Lgr5+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro", Cell Stem Cell, 6, pp.25~36 (2010)
14. DeWard, A. D., "Cellular heterogeneity in the mouse esophagus implicates the presence of a nonquiescent epithelial stem cell population", Cell Rep., 9, pp.701~711 (2014)
15. Date, S., "Mini-gut organoids : reconstitution of the stem cell niche", Annu. Rev. Cell Dev. Biol, 31, pp.269~289 (2015)
16. Kretzschmar, K., "Organoids : modeling development and the stem cell niche in a dish", Dev. Cell, 38, pp.590~600 (2016)
17. 민성진, "Gastrointestinal tract modeling using organoids engineered with cellular and microbiota niches", Experimental and Molecular Medicine, 52, pp.1~11 (2020), 생화학분자생물학회[DOI]
18. Nakamura, T., "Advancing intestinal organoid technology toward regenerative medicine", Cell. Mol. Gastroenterol. Hepatol, 5, pp.51~60 (2018)
19. Georgakopoulos, N., "Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids", BMC Dev. Biol, 20, pp.4~ (2020)
20. Ootani, A., "Sustained in vitro intestinal epithelial culture within a Wntdependent stem cell niche", Nat. Med, 15, pp.701~ (2009)
21. Li, X., "Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture", Nat. Med, 20, pp.769~777 (2014)
22. Spence, J. R., "Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro", Nature, 470, pp.105~109 (2011)
23. Múnera, J. O., "Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling", Cell Stem Cell, 21, pp.51~64 (2017)
24. McCracken, K. W., "Wnt", β-catenin promotes gastric fundus specification in mice and humans, 2017, pp.541, 182~187
25. McCracken, K. W., "Modelling human development and disease in pluripotent stem-cell-derived gastric organoids", Nature, 516, pp.400~404 (2014)
26. Trisno, S. L., "Esophageal organoids from human pluripotent stem cells delineate Sox2 functions during esophageal specification", Cell Stem Cell, 23, pp.501~515 (2018)
27. Takebe, T., "Vascularized and functional human liver from an iPSC-derived organ bud transplant", Nature, 499, pp.481~484 (2013)
28. Van De Wetering, M., "Prospective derivation of a living organoid biobank of colorectal cancer patients", Cell, 161, pp.933~945 (2015)
29. Fujii, M., "A colorectal tumor organoid library demonstrates progressive loss of niche factor requirements during tumorigenesis", Cell Stem Cell, 18, pp.827~838 (2016)
30. Ganesh, K., "A rectal cancer organoid platform to study individual responses to chemoradiation", Nat. Med, 25, pp.1607~1614 (2019)
31. Yao, Y., "Patient-derived organoids predict chemoradiation responses of locally advanced rectal cancer", Cell Stem Cell, 26, pp.17~26 (2020)
32. Ooft, S. N., "Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients", Sci. Transl. Med., 11, pp.eaay2574~ (2019)
33. Yan, H. H. N., "A comprehensive human gastric cancer organoid biobank captures tumor subtype heterogeneity and enables therapeutic screening", Cell Stem Cell, 23, pp.882~897 (2018)
34. Nanki, K., "Divergent routes toward Wnt and R-spondin niche independency during human gastric carcinogenesis", Cell, 174, pp.856~869 (2018)
35. Vlachogiannis, G., "Patient-derived organoids model treatment response of metastatic gastrointestinal cancers", Science, 926, pp.920~926 (2018)
36. Seidlitz, T., "Human gastric cancer modelling using organoids", Gut, 68, pp.207~217 (2019)
37. Gao, M., "Development of patient-derived gastric cancer organoids from endoscopic biopsies and surgical tissues", Ann. Surg. Oncol, 25, pp.2767~2775 (2018)
38. Steele, N. G., "An organoid-based preclinical model of human gastric cancer", Cell. Mol. Gastroenterol. Hepatol, 7, pp.161~184 (2019)
39. Li, X., "Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics", Nat. Commun, 9, pp.2983~ (2018)
40. Derouet, M. F., "Towards personalized induction therapy for esophageal adenocarcinoma : organoids derived from endoscopic biopsy recapitulate the pre-treatment tumor", Sci. Rep, 10, pp.14514~ (2020)
41. Kijima, T., "Three-dimensional organoids reveal therapy resistance of esophageal and oropharyngeal squamous cell carcinoma cells", Cell. Mol. Gastroenterol. Hepatol, 7, pp.73~91 (2018)
42. Broutier, L., "Human primary liver cancer–derived organoid cultures for disease modeling and drug screening", Nat. Med, 23, pp.1424~ (2017)
43. Nuciforo, S., "Organoid models of human liver cancers derived from tumor needle biopsies", Cell Rep, 24, pp.1363~1376 (2018)
44. Li, L., "Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity", JCI Insight, 4, pp.e121490~ (2019)
45. Tiriac, H., "Organoid profiling identifies common responders to chemotherapy in pancreatic cancer", Cancer Discov, 8, pp.1112~1129 (2018)
46. Seino, T., "Human pancreatic tumor organoids reveal loss of stem cell niche factor dependence during disease progression", Cell Stem Cell, 22, pp.454~467 (2018)
47. Driehuis, E., "Pancreatic cancer organoids recapitulate disease and allow personalized drug screening", Proc. Natl Acad. Sci. USA, 116, pp.26580~26590 (2019)
48. Kawasaki, K., "An organoid biobank of neuroendocrine neoplasms enables genotype-phenotype mapping", Cell, 183, pp.1420~1435 (2020)
49. Cristobal, A., "Personalized proteome profiles of healthy and tumor human colon organoids reveal both individual diversity and basic features of colorectal cancer", Cell Rep, 18, pp.263~274 (2017)
50. The Cancer Genome Atlas Research Network, "Comprehensive molecular characterization of human colon and rectal cancer", Nature, 487, pp.330~337 (2012)
51. The Cancer Genome Atlas Research Network, "Comprehensive molecular characterization of gastric adenocarcinoma", Nature, 513, pp.202~209 (2014)
52. The Cancer Genome Atlas Research Network, "Integrated genomic characterization of oesophageal carcinoma", Nature, 541, pp.169~ (2017)
53. Moffitt, R. A., "Virtual microdissection identifies distinct tumor-and stromaspecific subtypes of pancreatic ductal adenocarcinoma", Nat. Genet, 47, pp.1168~1178 (2015)
54. Bosman, F., "WHO Classification of Tumours of the Digestive System, Vol. 3" (2010), IARC Press
55. Barretina, J., "The cancer cell line encyclopedia enables predictive modelling of anticancer drug sensitivity", Nature, 483, pp.603~607 (2012)
56. Kamb, A., "What’s wrong with our cancer models?", Nat. Rev. Drug Discov., 4, pp.161~165 (2005)
57. Du, Y., "Development of a miniaturized 3D organoid culture platform for ultra-high throughput screening", J. Mol. Cell Biol. (2020)[DOI]
58. Roerink, S. F., "Intra-tumour diversification in colorectal cancer at the singlecell level", Nature, 556, pp.457~462 (2018)
59. Schumacher, D., "Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures", PLoS Genet, 15, pp.e1008076~ (2019)
60. Vitale, I., "Macrophages and metabolism in the tumor microenvironment", Cell Metab., 30, pp.36~50 (2019)
61. Joyce, J. A., "T cell exclusion, immune privilege, and the tumor microenvironment", Science, 348, pp.74~80 (2015)
62. Quail, D. F., "Microenvironmental regulation of tumor progression and metastasis", Nat. Med, 19, pp.1423~1437 (2013)
63. "Fibroblast heterogeneity in the cancer wound", J. Exp. Med, 211, pp.1503~1523 (2014)
64. Kalluri, R., "The biology and function of fibroblasts in cancer", Nat. Rev. Cancer, 16, pp.582~598 (2016)
65. "Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer", J. Exp. Med, 214, pp.579~596 (2017)
66. Trédan, O., "Drug resistance and the solid tumor microenvironment", J. Natl Cancer Inst, 99, pp.1441~1454 (2007)
67. Tsai, S., "Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models", BMC Cancer, 18, pp.335~ (2018)
68. Sharma, P., "The future of immune checkpoint therapy", Science, 348, pp.56~61 (2015)
69. Sharma, P., "Immune checkpoint targeting in cancer therapy : toward combination strategies with curative potential", Cell, 161, pp.205~214 (2015)
70. Chen, D. S., "Elements of cancer immunity and the cancer–immune set point", Nature, 541, pp.321~330 (2017)
71. Finnberg, N. K., "Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures", Oncotarget, 8, pp.66747~66757 (2017)
72. Dijkstra, K. K., "Generation of tumor-reactive T cells by co-culture of peripheral blood lymphocytes and tumor organoids", Cell, 174, pp.1586~1598 (2018)
73. Cattaneo, C. M., "Tumor organoid–T-cell coculture systems", Nat. Protoc, 15, pp.15~39 (2020)
74. Joseph Cherng Huei Kong, "Tumor-Infiltrating Lymphocyte Function Predicts Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer", JCO Precision Oncology, (2), pp.1~15 (2018), American Society of Clinical Oncology (ASCO)[DOI]
75. June, C. H., "Chimeric antigen receptor therapy", N. Engl. J. Med., 379, pp.64~73 (2018)
76. Schnalzger, T. E., "3D model for CAR-mediated cytotoxicity using patientderived colorectal cancer organoids", EMBO J, 38, pp.e100928~ (2019)
77. Drost, J., "Sequential cancer mutations in cultured human intestinal stem cells", Nature, 521, pp.43~47 (2015)
78. Matano, M., "Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids", Nat. Med, 21, pp.256~ (2015)
79. Fumagalli, A., "Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids", Proc. Natl Acad. Sci. USA, 114, pp.E2357~E2364 (2017)
80. de Sousa e Melo, F., "A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer", Nature, 543, pp.676~680 (2017)
81. Roper, J., "In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis", Nat. Biotechnol, 35, pp.569~576 (2017)
82. O’Rourke, K. P., "Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer", Nat. Biotechnol, 35, pp.577~582 (2017)
83. Artegiani, B., "Probing the tumor suppressor function of BAP1 in CRISPR-engineered human liver organoids", Cell Stem Cell, 24, pp.927~943 (2019)
84. Fessler, E., "TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype", EMBO Mol. Med, 8, pp.745~760 (2016)
85. Kawasaki, K., "Chromosome engineering of human colon-derived organoids to develop a model of traditional serrated adenoma", Gastroenterology, 158, pp.638~651 (2020)
86. Verissimo, C. S., "Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening", Elife, 5, pp.e18489~ (2016)
87. Janda, C. Y., "Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling", Nature, 545, pp.234~237 (2017)
88. Mihara, E., "Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin", α-albumin, 2016, pp.5, e11621~

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