Functional and pathologic association of aminoacyl-tRNA synthetases with cancer

참고문헌 (105)

1. Kwon, N. H., "Aminoacyl-tRNA synthetases as therapeutic targets", Nat. Rev. Drug Discov, 18, pp.629~650 (2019)
2. Jia, J., "WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression", Mol. Cell, 29, pp.679~690 (2008)
3. Kim, S., "C-terminal peptide appendix in a class I tRNA synthetase needed for acceptor-helix contacts and microhelix aminoacylation", Biochemistry, 32, pp.13026~13031 (1993)
4. Ahn, H. -C., "Solution structure and p43 binding of the p38leucine zipper motif: coiled-coil interactions mediate the association between p38 and p43", FEBS Lett, 542, pp.119~124 (2003)
5. Csank, C., "Isoleucyl-tRNA synthetase from the ciliated protozoan Tetrahymena thermophila. DNA sequence, gene regulation, and leucine zipper motifs", J. Biol. Chem, 267, pp.4592~4599 (1992)
6. Sampath, P., "Noncanonical Function of Glutamyl-Prolyl-tRNA Synthetase", Cell, 119, pp.195~208 (2004)
7. Lee, S. W., "Multifunctional proteins in tumorigenesis:aminoacyl-tRNA synthetases and translational components", Curr. Proteom, 3, pp.233~247 (2006)
8. Samadder, A., "tRN-A-RS Acts As Biomarker for Cancer and Other Diseases", J. Mol. Biomark. Diagn., S2, pp.019~ (2016)
9. Arif, A., "Two-site phosphorylation of EPRS coordinates multimodal regulation of noncanonical translational control activity", Mol. Cell, 35, pp.164~180 (2009)
10. Seung-Hun Shin, "Implication of leucyl-tRNA synthetase 1 (LARS1)over-expression in growth and migration of lung cancer cellsdetected by siRNA targeted knock-down analysis", Experimental and Molecular Medicine, 40(2), pp.229~236 (2008), 생화학분자생물학회
11. Holleman, A., "Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment", N. Engl. J. Med, 351, pp.533~542 (2004)
12. Vellaichamy, A., "Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases", PLoS One, 4, pp.e7075~ (2009)
13. Wasenius, V. M., "Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are upregulated in papillary thyroid carcinoma : a cDNA and tissue microarray study", Clin. Cancer Res, 9, pp.68~75 (2002)
14. Shan, J., "The C", ebp-Atf response element(CARE)location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation, 2016, pp.44, 9719~9732
15. Shan, J., "Increased transcription of the seryltRNA synthetase (SARS) gene in response to amino acid limitation is mediated by an intronic C", EBP-ATF response element (CARE) that functions as an distal enhancer, 2017, pp.31, 644.1~
16. Andersson, R., "A unified architecture of transcriptional regulatory elements", Trends Genet, 31, pp.426~433 (2015)
17. Singleton, D. C., "Targeting the ATF4 pathway in cancer therapy", Expert Opin. Ther. Targets, 16, pp.1189~1202 (2012)
18. Ben-Batalla, I., "Influence of androgens on immunity to self and foreign: effects on immunity and cancer", Front. Immunol, 11, pp.1184~ (2020)
19. Park, M. C., "Secreted human glycyl-tRNA synthetase implicated in defense against ERK-activated tumorigenesis", Proc. Natl. Acad. Sci. USA, 109, pp.E640~E647 (2012)
20. Katsyv, I., "EPRS is a critical regulator of cell proliferation and estrogen signaling in ER+ breast cancer", Oncotarget, 7, pp.69592~69605 (2016)
21. Zhou, H., "Transcriptomic signature predicts the distant relapse in patients with ER+ breast cancer treated with tamoxifen for five years", Mol. Med. Rep, 17, pp.3152~3157 (2018)
22. Tolstrup, A. B., "Transcriptional regulation of the interferon-graphic-inducible tryptophanyl-tRNA synthetase includes alternative splicing", J. Biol. Chem, 270, pp.397~403 (1995)
23. Ghanipour, A., "The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer", Cancer Epidemiol. Biomark. Prev, 18, pp.2949~2956 (2009)
24. Otani, A., "A fragment of human TrpRS as a potent antagonist of ocular angiogenesis", Proc. Natl. Acad. Sci. USA, 99, pp.178~183 (2001)
25. Kim, J. E., "An elongation factor-associating domain is inserted into human cysteinyl-tRNA synthetase by alternative splicing", Nucleic Acids Res, 28, pp.2866~2872 (2000)
26. Mimori, K., "Elongation factor 1 gamma mRNA expression in oesophageal carcinoma", Gut, 38, pp.66~70 (1996)
27. Lew, Y., "Expression of elongation factor-1 gamma-related sequence in human pancreatic cancer", Pancreas, 7, pp.144~152 (1992)
28. Chi, K., "Expression of an elongation factor 1 gammarelated sequence in adenocarcinomas of the colon", Gastroenterology, 103, pp.98~102 (1992)
29. Yao, P., "Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression", Cell, 149, pp.88~100 (2012)
30. Ray, P. S., "A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity", EMBO J, 26, pp.3360~3372 (2007)
31. Mukhopadhyay, R., "The GAIT system: a gatekeeper of inflammatory gene expression", Trends Biochem. Sci, 34, pp.324~331 (2009)
32. Chen, S. H., "A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity", Leukemia, 25, pp.66~74 (2010)
33. Vettore, L., "New aspects of amino acid metabolism in cancer", Br. J. Cancer, 122, pp.150~156 (2020)
34. He, Y., "Potentially functional polymorphisms in aminoacyl-tRNA synthetases genes are associated with breast cancer risk in a Chinese population", Mol. Carcinog, 54, pp.577~583 (2015)
35. Tian, T., "Polymorphisms in CARS are associated with gastric cancer risk : a two-stage case–control study in the Chinese population", Gastric Cancer, 20, pp.940~947 (2017)
36. Miyaki, M., "Alterations of repeated sequences in 5’ upstream and coding regions in colorectal tumors from patients with hereditary nonpolyposis colorectal cancer and Turcot syndrome", Oncogene, 20, pp.5215~5218 (2001)
37. Sang Wook Park, "Frameshift Mutation of MARS Gene Encoding an Aminoacyl-tRNA Synthetase in Gastric and Colorectal Carcinomas with Microsatellite Instability", Gut and Liver, 4(3), pp.430~431 (2010), 거트앤리버 소화기연관학회협의회
38. Debelenko, L. V., "Identification of CARS-ALK Fusion in Primary and Metastatic Lesions of an Inflammatory Myofibroblastic Tumor", Lab. Investig, 83, pp.1255~1265 (2003)
39. Cools, J., "Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor", Genes Chromosomes Cancer, 34, pp.354~362 (2002)
40. Ubeda, M., "CHOP", GADD153 and methionyl-tRNA synthetase(MetRS)genes overlap in a conserved region that controls mRNA stability, 1999, pp.262, 31~38
41. Zhou, W., "Inactivation of LARS2, located at the commonly deleted region 3p21.3, by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma", Acta Biochim. Biophys. Sin, 41, pp.54~62 (2009)
42. Bottoni, A., "miR-15a and miR-16-1 down-regulation in pituitary adenomas", J. Cell. Physiol, 204, pp.280~285 (2005)
43. Aqeilan, R. I., "miR-15a and miR-16-1 in cancer : discovery, function and future perspectives", Cell Death Differ, 17, pp.215~220 (2010)
44. Uhlén, M., "A human protein atlas for normal and cancer tissues based on antibody proteomics", Mol. Cell. Proteom, 4, pp.1920~1932 (2005)
45. Park, S. G., "Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response", Proc. Natl. Acad. Sci. USA, 102, pp.6356~6361 (2005)
46. Kushner, J. P., "Elevated methionine-tRNA synthetase activity in human colon cancer", Proc. Soc. Exp. Biol. Med, 153, pp.273~276 (1976)
47. Jang, S. I., "New staining method using methionyl-tRNA synthetase 1 antibody for brushing cytology of bile duct cancer", Gastrointest. Endosc, 92, pp.310~319 (2020)
48. Zhou, Z., "Roles of Aminoacyl-tRNA Synthetases in Cancer", Front. Cell Dev. Biol, 8, pp.599765~ (2020)
49. Gao, G., "A human leucyl-tRNA synthetase as an anticancer target", Onco-Targets Ther, 8, pp.2933~2942 (2015)
50. Rubio Gomez, M. A., "Aminoacyl-tRNA synthetases", RNA, 26, pp.910~936 (2020)
51. Kim, E. Y., "Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer", Ther. Adv. Med. Oncol, 11, pp.1758835919846798~ (2019)
52. Huang, H., "iPTMnet : an integrated resource for protein post-translational modification network discovery", Nucleic Acids Res, 46, pp.D542~D550 (2018)
53. Kim, D. G., "Chemical inhibition of prometastatic lysyl-tRNA synthetaselaminin receptor interaction", Nat. Chem. Biol, 10, pp.29~34 (2014)
54. Boulos, S., "Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma", Oncotarget, 8, pp.65186~65198 (2017)
55. Kim, S. B., "Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells", J. Cell Biol, 216, pp.2201~2216 (2017)
56. Suh, J. H., "Plasma lysyl-tRNA synthetase 1(KARS1)as a novel diagnostic and monitoring biomarker for colorectal cancer", J. Clin. Med, 9, pp.533~ (2020)
57. Kwon, N. H., "Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3", Proc. Natl. Acad. Sci. USA, 108, pp.19635~ (2011)
58. Park, B. J., "The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM", ATR, 2005, pp.120, 209~221
59. Park, B. J., "AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability", Cancer Res, 66, pp.6913~6918 (2006)
60. Lee, J. Y., "Promiscuous methionyl-tRNA synthetase mediates adaptive mistranslation to protect cells against oxidative stress", J. Cell Sci, 127, pp.4234~4245 (2014)
61. Arif, A., "Phosphorylation of glutamylprolyl tRNA synthetase by cyclin-dependent kinase 5 dictates transcript-selective translational control", Proc. Natl. Acad. Sci. U. S. A, 108, pp.1415~1420 (2011)
62. Arif, A., "EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice", Nature, 542, pp.357~361 (2017)
63. Yoon, I., "Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1", Science, 367, pp.205~ (2020)
64. Cho, S., "Endogenous TLR2 ligand embedded in the catalytic region of human cysteinyl-tRNA synthetase 1", J. Immunother. Cancer, 8, pp.e000277~ (2020)
65. Bernstein, R. M., "Cellular protein and RNA antigens in autoimmune disease", Mol. Biol. Med, 2, pp.105~120 (1984)
66. Williams, T. F., "Secreted Threonyl-tRNA synthetase stimulates endothelial cell migration and angiogenesis", Sci. Rep, 3, pp.1317~ (2013)
67. Cao, Z., "Noncanonical function of threonyl-tRNA synthetase regulates vascular development in zebrafish", Biochem. Biophys. Res. Commun, 473, pp.67~72 (2016)
68. Kim, S. B., "Exosomal secretion of truncated cytosolic lysyl-tRNA synthetase induces inflammation during cell starvation", Cell Stress, 2, pp.119~121 (2018)
69. Wakasugi, K., "Two distinct cytokines released from a human aminoacyl-tRNA synthetase", Science, 284, pp.147~151 (1999)
70. Greenberg, Y., "The novel fragment of tyrosyl tRNA synthetase, mini-TyrRS, is secreted to induce an angiogenic response in endothelial cells", FASEB J, 22, pp.1597~1605 (2008)
71. Wakasugi, K., "Highly differentiated motifs responsible for two cytokine activities of a split human tRNA synthetase", J. Biol. Chem, 274, pp.23155~23159 (1999)
72. Wakasugi, K., "Induction of angiogenesis by a fragment of human tyrosyltRNA synthetase", J. Biol. Chem, 277, pp.20124~20126 (2002)
73. Turpaev, K. T., "Alternative processing of the tryptophanyl-tRNA synthetase mRNA from interferon-treated human cells", Eur. J. Biochem, 240, pp.732~737 (1996)
74. Wakasugi, K., "A human aminoacyl-tRNA synthetase as a regulator of angiogenesis", Proc. Natl Acad. Sci. U.S.A, 99, pp.173~177 (2002)
75. Zhou, Q., "Orthogonal use of a human tRNA synthetase active site to achieve multifunctionality", Nat. Struct. Mol. Biol, 17, pp.57~61 (2010)
76. Tzima, E., "VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function", J. Biol. Chem, 280, pp.2405~2408 (2005)
77. Kim, S., "Aminoacyl-tRNA synthetases and tumorigenesis:more than housekeeping", Nat. Rev. Cancer, 11, pp.708~718 (2011)
78. Kim, J. H., "Protein–protein interactions and multi-component complexes of aminoacyl-tRNA synthetases", Top. Curr. Chem, 344, pp.119~144 (2013)
79. Fu, C. Y., "Competitive binding between Seryl-tRNA synthetase", YY1 complex and NFKB1 at the distal segment results in differential regulation of human vegfa promoter activity during angiogenesis, 2017, pp.45, 2423~2437
80. Jeong, S. J., "A threonyl-tRNA synthetase-mediated translation initiation machinery.", Nat. Commun, 10, pp.1357~ (2019)
81. Choi, J. W., "Cancer-associated splicing variant of tumor suppressor AIMP2", p38 : pathological implication in tumorigenesis, 2011, pp.7, e1001351~
82. Choi, J. W., "Splicing variant of AIMP2 as an effective target against chemoresistant ovarian cancer", J. Mol. Cell Biol, 4, pp.164~173 (2012)
83. Lim, S., "Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development", Nat. Chem. Biol, 16, pp.31~41 (2020)
84. Han, JungM., "Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway", Cell, 149, pp.410~442 (2012)
85. Wolfson, R. L., "Sestrin2 is a leucine sensor for the mTORC1 pathway", Science, 351, pp.43~48 (2015)
86. Wang, S., "Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1", Science, 347, pp.188~194 (2015)
87. Chantranupong, L., "The CASTOR proteins are arginine sensors for the mTORC1 pathway", Cell, 165, pp.153~164 (2016)
88. Gu, X., "SAMTOR is an S-adenosylmethionine sensor for the mTORC1pathway", Science, 358, pp.813~818 (2017)
89. Lee, M., "Coordination of the leucine-sensing Rag GTPase cycle by leucyltRNA synthetase in the mTORC1 signaling pathway", Proc. Natl. Acad. Sci. USA, 115, pp.E5279~E5288 (2018)
90. Yoon, M. S., "Leucyl-tRNA synthetase activates Vps34 in amino acid-sensing mTORC1 signaling", Cell Rep, 16, pp.1510~1517 (2016)
91. Bonfils, G., "Leucyl-tRNA synthetase controls TORC1 via the EGO complex", Mol. Cell, 46, pp.105~110 (2012)
92. Kim, J. H., "Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction", Nat. Commun, 8, pp.732~ (2017)
93. Lukk, M., "A global map of human gene expression", Nat. Biotechnol, 28, pp.322~324 (2010)
94. Chen, L., "Targeting glutamine induces apoptosis : a cancer therapy approach", Int. J. Mol. Sci, 16, pp.22830~22855 (2015)
95. Matés, J. M., "Pathways from glutamine to apoptosis", Front. Biosci, 11, pp.3164~3180 (2006)
96. Ko, Y. -G., "Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1", J. Biol. Chem, 276, pp.6030~6036 (2001)
97. Kwon, N. H., "Stabilization of cyclin-dependent kinase 4 by methionyl-tRNA synthetase in p16INK4a-negative cancer", ACS Pharmacol. Transl. Sci, 1, pp.21~31 (2018)
98. Musgrove, E. A., "Cyclin D as a therapeutic target in cancer", Nat. Rev. Cancer, 11, pp.558~572 (2011)
99. Roe, S. M., "The mechanism of Hsp90 regulation by the protein kinasespecific cochaperone p50(cdc37)", Cell, 116, pp.87~98 (2004)
100. Witkiewicz, A. K., "The meaning of p16(ink4a)expression in tumors : functional significance, clinical associations and future developments", Cell Cycle, 10, pp.2497~2503 (2011)
101. Sajish, M., "Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γand p53 signaling", Nat. Chem. Biol, 8, pp.547~554 (2012)
102. Tshori, S., "Amino-acyl tRNA synthetases generate dinucleotide polyphosphates as second messengers : functional implications", Top. Curr. Chem, 344, pp.189~206 (2014)
103. Brevet, A., "In vivo synthesis of adenylylated bis(5’-nucleosidyl)tetraphosphates(Ap4N)by Escherichia coli aminoacyl-tRNA synthetases", Proc. Natl. Acad. Sci. USA, 86, pp.8275~8279 (1989)
104. Lee, Y. -N., "The function of Lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in Fc RI-activated mast cells", Immunity, 20, pp.145~151 (2004)
105. Yoon, S., "Discovery of(S)-4-isobutyloxazolidin-2-one as a novel leucyl-tRNA synthetase(LRS)-targeted mTORC1 inhibitor", Bioorg. Med. Chem. Lett, 26, pp.3038~3041 (2016)

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