Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense system

참고문헌 (69)

1. Alfadda, A. A., "Reactive oxygen species in health and disease", J. Biomed. Biotechnol, 2012, pp.936486~ (2012)
2. Auten, R. L., "Oxygen toxicity and reactive oxygen species : the devil is in the details", Pediatr. Res, 66, pp.121~127 (2009)
3. Wilson, C., "Oxidative stress and osteoporosis", Nat. Rev. Endocrinol, 10, pp.3~3 (2014)
4. Balaban, R. S., "Mitochondria, oxidants, and aging", Cell, 120, pp.483~495 (2005)
5. Gao, J., "SIRT3", SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress, 2018, pp.25, 229~240
6. Callaway, D. A., "Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases", J. Bone Mineral Metabolism, 3, pp.359~370 (2015)
7. Yang, K., "Three classes of antioxidant defense systems and the development of postmenopausal osteoporosis", Front. Physiol, 13, pp.840293~ (2022)
8. Lepetsos, P., "ROS", oxidative stress signaling in osteoarthritis, 2016, pp.1862, 576~591
9. He, L., "Antioxidants maintain cellular redox homeostasis by elimination of reactive oxygen species", Cell. Physiol. Biochem, 44, pp.532~553 (2017)
10. Andreyev, A. Y., "Mitochondrial metabolism of reactive oxygen species", Biochemistry, 70, pp.200~214 (2005)
11. Chen, A. C., "A phase 3 randomized trial of nicotinamide for skin-cancer chemoprevention", N. Engl. J. Med, 373, pp.1618~1626 (2015)
12. Srivastava, S., "Emerging therapeutic roles for NAD+ metabolism in mitochondrial and age-related disorders", Clin. Transl. Med, 5, pp.25~ (2016)
13. Cantó, C., "The NAD(+)precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity", Cell Metab, 15, pp.838~847 (2012)
14. Kim, H. J., "ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation", Cell Mol. Life Sci, 79, pp.155~ (2022)
15. Shin, H. R., "Excessive osteoclast activation by osteoblast paracrine factor RANKL is a major cause of the abnormal long bone phenotype in Apert syndrome model mice", J. Cell. Physiol, 237, pp.2155~2168 (2022)
16. Park, O. -J., "FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization", J. Biol. Chem, 285, pp.3568~3574 (2010)
17. Yoon, W. -J., "Prolyl isomerase Pin1-mediated conformational change and subnuclear focal accumulation of Runx2 Are crucial for fibroblast growth factor 2(FGF2)-induced osteoblast differentiation", J. Biol. Chem, 289, pp.8828~8838 (2014)
18. Langmead, B., "Fast gapped-read alignment with Bowtie 2", Nat. Methods, 9, pp.357~359 (2012)
19. Danecek, P., "Twelve years of SAMtools and BCFtools", GigaScience, 10, pp.giab008~ (2021)
20. Tarasov, A., "Sambamba : fast processing of NGS alignment formats", Bioinformatics, 31, pp.2032~2034 (2015)
21. "BCBIo-nextgen v1.2.9"[URL]
22. Patro, R., "Salmon provides fast and bias-aware quantification of transcript expression", Nat. Methods, 14, pp.417~419 (2017)
23. Bray, N. L., "Near-optimal probabilistic RNAseq quantification", Nat. Biotechnol, 34, pp.525~527 (2016)
24. Love, M. I., "Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2", Genome Biol, 15, pp.550~ (2014)
25. Wu, T., "clusterProfiler 4.0: A universal enrichment tool for interpreting omics data", Innovation, 2, pp.100141~ (2021)
26. "R package ‘corrplot’: visualization of a correlation matrix" (2021)[URL]
27. Oliver, K. L., "Harnessing gene expression networks to prioritize candidate epileptic encephalopathy genes", PLoS ONE, 9, pp.e102079~ (2014)
28. Miller, H. E, "Correlation AnalyzeR: functional predictions from gene co-expression correlations", BMC Bioinformatics, 22, pp.206~ (2021)
29. Olmos, Y., "Mutual dependence of Foxo3a and PGC-1α in the induction of oxidative stress genes", J. Biol. Chem, 284, pp.14476~14484 (2009)
30. Austin, S., "PGC1α and mitochondrial metabolism – emerging concepts and relevance in ageing and neurodegenerative disorders", J. Cell Sci, 125, pp.4963~4971 (2012)
31. Brown, K. D., "Activation of SIRT3 by the NAD+ precursor nicotinamide riboside protects from noise-induced hearing loss", Cell Metabolism, 20, pp.1059~1068 (2014)
32. Wan, H. F., "Nicotinamide induces liver regeneration and improves liver function by activating SIRT1", Mol. Med. Rep (2018)[DOI]
33. Zhang, J., "Mitochondrial Sirtuin 3 : New emerging biological function and therapeutic target", Theranostics, 10, pp.8315~8342 (2020)
34. Kenny, T. C., "From discovery of the CHOP axis and targeting ClpP to the identification of additional axes of the UPRmt driven by the estrogen receptor and SIRT3", J. Bioenerg. Biomembr, 49, pp.297~305 (2017)
35. Jacobs, K. M., "SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression", Int. J. Biol. Sci, 4, pp.291~299 (2008)
36. Tseng, A. H., "SIRT3 interactions with FOXO3acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia", Biochem. J, 464, pp.157~168 (2014)
37. Kim, H. -J., "Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells", Oncotarget, 8, pp.6608~6622 (2017)
38. Ding, G., "Allicin inhibits oxidative stress-induced mitochondrial dysfunction and apoptosis by promoting PI3K", AKT and CREB, Exp. Ther. Med, pp.2016, 11[DOI]
39. Malik, A. N., "Accurate quantification of mouse mitochondrial DNA without co-amplification of nuclear mitochondrial insertion sequences", Mitochondrion, 29, pp.59~64 (2016)
40. Quiros, P. M., "Analysis of mtDNA", nDNA ratio in mice, 2017, pp.7, 47~54
41. Basu, S., "Association between oxidative stress and bone mineral density", Biochem. Biophys. Res. Commun, 288, pp.275~279 (2001)
42. Jessica N. Peoples, "Mitochondrial dysfunction and oxidative stress in heart disease", Experimental and Molecular Medicine, 51, pp.1~13 (2019), 생화학분자생물학회[DOI]
43. Stope, M. B., "Phosphorylation of histone H2A.X as a DNA‑associated biomarker (Review)", World Acad. Sci. J, 3, pp.31~ (2021)
44. Kannan, K., "Oxidative stress and apoptosis", Pathophysiology, 7, pp.153~163 (2000)
45. Arfin, S., "Oxidative stress in cancer cell metabolism", Antioxidants (2021)[DOI]
46. Sena, L. A., "Physiological roles of mitochondrial reactive oxygen species", Mol. Cell, 48, pp.158~167 (2012)
47. Goettsch, C., "NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis", Journal Clin. Investig, 123, pp.4731~4738 (2013)
48. Zahan, O. M., "The evaluation of oxidative stress in osteoarthritis", Med. Pharm. Rep, 93, pp.12~22 (2020)
49. Schoppa, A. M., "Osteoblast lineage Sod2 deficiency leads to an osteoporosislike phenotype in mice", Dis. Model Mech (2022)[DOI]
50. Jun, J. H., "N-acetylcysteine stimulates osteoblastic differentiation of mouse calvarial cells", J. Cell. Biochem, 103, pp.1246~1255 (2008)
51. Russell, A. P., "Skeletal muscle mitochondria:a major player in exercise, health and disease", Biochim. Biophys. Acta, 1840, pp.1276~1284 (2014)
52. Li, Q., "The role of mitochondria in osteogenic, adipogenic and chondrogenic differentiation of mesenchymal stem cells", Protein Cell, 8, pp.439~445 (2017)
53. Shum, L. C., "Energy metabolism in mesenchymal stem cells during osteogenic differentiation", Stem Cells Dev, 25, pp.114~122 (2016)
54. Forni, M. F., "Murine mesenchymal stem cell commitment to differentiation is regulated by mitochondrial dynamics", Stem Cells, 34, pp.743~755 (2016)
55. Long, A. N., "Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model", BMC Neurol, 15, pp.19~ (2015)
56. Infante, A., "Osteogenesis and aging: lessons from mesenchymal stem cells", Stem Cell Res.Therapy, 9, pp.244~ (2018)
57. Qiao, X., "Irisin promotes osteoblast proliferation and differentiation via activating the MAP kinase signaling pathways", Sci. Rep, 6, pp.18732~ (2016)
58. Lee, H. W., "Histone deacetylase 1-mediated histone modification regulates osteoblast differentiation", Mol Endocrinol, 20, pp.2432~2443 (2006)
59. Jensen, E. D., "Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner", J. Bone Miner. Res, 23, pp.361~372 (2008)
60. Bae, H. -S., "An HDAC inhibitor, entinostat", MS-275, partially prevents delayed cranial suture closure in heterozygous Runx2 null mice, 2017, pp.32, 951~961
61. Kim, H. -N., "Histone deacetylase inhibitor MS-275 stimulates bone formation in part by enhancing Dhx36-mediated TNAP transcription", J. Bone Mineral Res, 26, pp.2161~2173 (2011)
62. Ho, L., "Sirtuin-3 promotes adipogenesis, osteoclastogenesis, and bone loss in aging male mice", Endocrinology, 158, pp.2741~2753 (2017)
63. Ling, W, "Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency", JCI Insight (2021)[DOI]
64. Iyer, S., "FOXOs attenuate bone formation by suppressing Wnt signaling", J. Clin. Investig, 123, pp.3409~3419 (2013)
65. Ambrogini, E., "FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice", Cell Metabolism, 11, pp.136~146 (2010)
66. Thoma, A., "Targeting reactive oxygen species (ROS) to combat the age-related loss of muscle mass and function", Biogerontology, 21, pp.475~484 (2020)
67. Mouchiroud, L., "The NAD(+)", sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling, 2013, pp.154, 430~441
68. Zhang, H., "NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice", Science, 352, pp.1436~1443 (2016)
69. Sedelnikova, O. A., "Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks", Nat. Cell Biol, 6, pp.168~170 (2004)

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