Lactobacillus-derived extracellular vesicles counteract Aβ42-induced abnormal transcriptional changes through the upregulation of MeCP2 and Sirt1 and improve Aβ pathology in Tg-APP/PS1 mice

참고문헌 (60)

1. Long, J. M., "Alzheimer disease: an update on pathobiology and treatment strategies", Cell, 179, pp.312~339 (2019)
2. Scheltens, P., "Alzheimer’s disease", Lancet, 397, pp.1577~1590 (2021)
3. Alvira-Botero, X., "Clearance of amyloid-β peptide across the choroid plexus in Alzheimer’s disease", Curr. Aging Sci, 3, pp.219~229 (2010)
4. Tarasoff-Conway, J. M., "Clearance systems in the brain—implications for Alzheimer disease", Nat. Rev. Neurol, 11, pp.457~470 (2015)
5. Birch, A. M., "Modulation of inflammation in transgenic models of Alzheimer’s disease", J. Neuroinflammation, 11, pp.25~ (2014)
6. Kinney, J. W., "Inflammation as a central mechanism in Alzheimer’s disease", Alzheimers Dement, 4, pp.575~590 (2018)
7. Myers, A., "Overview of transgenic mouse models for Alzheimer’s disease", Curr. Protoc. Neurosci, 89, pp.e81~ (2019)
8. Karol Kowalski, "Brain-Gut-Microbiota Axis in Alzheimer’s Disease", Journal of Neurogastroenterology and Motility (JNM), 25(1), pp.48~60 (2019), 대한소화기 기능성질환∙운동학회[DOI]
9. Nagu, P., "Gut microbiota composition and epigenetic molecular changes connected to the pathogenesis of Alzheimer’s disease", J. Mol. Neurosci, 71, pp.1436~1455 (2021)
10. Juli Choi, "Extracellular Vesicles Derived from Lactobacillus plantarum Increase BDNF Expression in Cultured Hippocampal Neurons and Produce Antidepressant-like Effects in Mice", Experimental Neurobiology, 28(2), pp.158~171 (2019), 한국뇌신경과학회
11. Choi, J., "Extracellular vesicles from Gram-positive and Gram-negative probiotics remediate stress-induced depressive behavior in mice", Mol. Neurobiol, 59, pp.2715~2728 (2022)
12. Ji Hyun Choi, "Lactobacillus paracasei-derived extracellular vesicles attenuate the intestinal inflammatory response by augmenting the endoplasmic reticulum stress pathway", Experimental and Molecular Medicine, 52, pp.1~15 (2020), 생화학분자생물학회[DOI]
13. Bannister, A. J., "Regulation of chromatin by histone modifications", Cell Res, 21, pp.381~395 (2011)
14. Campbell, R. R., "How the epigenome integrates information and reshapes the synapse", Nat. Rev. Neurosci, 20, pp.133~147 (2019)
15. Fuks, F., "The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation", J. Biol. Chem, 278, pp.4035~4040 (2003)
16. Lee, W., "MeCP2 regulates gene expression through recognition of H3K27me3", Nat. Commun, 11, pp.3140~ (2020)
17. Karpova, N. N., "Epigenetic basis of neuronal and synaptic plasticity", Curr. Top. Med. Chem, 17, pp.771~793 (2014)
18. Duclot, F., "Epigenetic mechanisms underlying the role of brainderived neurotrophic factor in depression and response to antidepressants", J. Exp. Biol, 218, pp.21~31 (2015)
19. Liu, X., "The epigenetics of Alzheimer’s disease : factors and therapeutic implications", Front. Genet, 9, pp.579~ (2018)
20. Abuhatzira, L., "MeCP2 deficiency in the brain decreases BDNF levels by REST", CoREST-mediated repression and increases TRKB production, 2007, pp.2, 214~222
21. Kline, D. D., "Exogenous brain-derived neurotrophic factor rescues synaptic dysfunction in Mecp2-null mice", J. Neurosci, 30, pp.5303~5310 (2010)
22. Choi, J., "Hyperoxygenation revitalizes Alzheimer’s disease pathology through the upregulation of neurotrophic factors", Aging Cell, 18, pp.e12888~ (2019)
23. Klein, M. E., "Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA", Nat. Neurosci, 10, pp.1513~1514 (2007)
24. Larimore, J. L., "Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-Associated MECP2 mutations", Neurobiol. Dis, 34, pp.199~211 (2009)
25. Sartor, G. C., "Enhancement of BDNF expression and memory by HDAC inhibition requires BET bromodomain reader proteins", J. Neurosci, 39, pp.612~626 (2019)
26. Lee, J. E., "Aging-dependent downregulation of SUV39H1histone methyltransferase increases susceptibility to stress-induced depressive behavior", Mol. Neurobiol, 58, pp.6427~6442 (2021)
27. Hock, C., "Region-specific neurotrophin imbalances in Alzheimer disease decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas", Arch. Neurol, 57, pp.846~851 (2000)
28. Du, Y., "Postmortem brain, cerebrospinal fluid, and blood neurotrophic factor levels in Alzheimer’s disease : a systematic review and meta-analysis", J. Mol. Neurosci, 65, pp.289~300 (2018)
29. Chao, M. V., "Neurotrophines and their receptors", Nat. Rev. Neurosci, 4, pp.299~309 (2003)
30. Devi, L., "7, 8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer’s disease", Neuropsychopharmacology, 37, pp.434~444 (2012)
31. Zhang, Z., "7, 8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer’s disease", Neuropsychopharmacology, 39, pp.638~650 (2014)
32. Jankowsky, J. L., "Co-expression of multiple transgenes in mouse CNS : a comparison of strategies", Biomol. Eng, 17, pp.157~165 (2001)
33. Lee, J. E., "Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice", Commun. Biol, 3, pp.292~ (2020)
34. Kim, T. K., "G9a-mediated regulation of OXT and AVP expression in the basolateral amygdala mediates stress-induced lasting behavioral depression and its reversal by exercise", Mol. Neurobiol, 53, pp.2843~2856 (2016)
35. Lee, E. H., "Repeated exposure with short-term behavioral stress resolves pre-existing stress-induced depressive-like behavior in mice", Nat. Commun, 12, pp.6682~ (2021)
36. Park, J. Y., "Behavioral engagement with playable objects resolves stressinduced adaptive changes by reshaping the reward system", Biol. Psychiatry, 91, pp.676~689 (2022)
37. Plaisier, S. B., "Rank-rank hypergeometric overlap : identification of statistically significant overlap between geneexpression signatures", Nucleic Acids Res, 38, pp.e169~ (2010)
38. Amidfar, M., "The role of CREB and BDNF in neurobiology and treatment of Alzheimer’s disease", Life Sci, 257, pp.118020~ (2020)
39. Goldberg, E. M., "Mechanisms of epileptogenesis : a convergence on neural circuit dysfunction", Nat. Rev. Neurosci, 14, pp.337~349 (2014)
40. Fontanet, P. A., "Pea3 transcription factors, Etv4 and Etv5, are required for proper hippocampal dendrite development and plasticity", Cereb. Cortex, 28, pp.236~249 (2018)
41. Im, H. I., "MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212", Nat. Neurosci, 13, pp.120~1127 (2010)
42. Mitchelmore, C., "Brain derived neurotrophic factor : epigenetic regulation in psychiatric disorders", Brain Res, 1586, pp.162~172 (2014)
43. Gill, S., "Extracellular membrane vesicles in the three domains of life and beyond", FEMS Microbiol. Rev, 43, pp.273~303 (2019)
44. Filip, R., "An update on the role of extracellular vesicles in the pathogenesis of necrotizing enterocolitis and inflammatory bowel diseases", Cells, 10, pp.3202~ (2021)
45. Ñahui Palomino, R. A., "Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues", Nat. Commun, 10, pp.5656~ (2019)
46. Zocchi, L., "SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression", Epigenetics, 7, pp.695~700 (2012)
47. Yan, D., "Effects of aluminium on long-term memory in rats and on SIRT1mediating the transcription of CREB-dependent gene in hippocampus", Basic Clin. Pharmacol. Toxicol, 121, pp.342~352 (2017)
48. Bramham, C. R., "BDNF function in adult synaptic plasticity : the synaptic consolidation hypothesis", Prog. Neurobiol, 76, pp.99~125 (2005)
49. Ghiglieri, V., "TrkB", BDNF-dependent striatal plasticity and behavior in a genetic model of epilepsy : modulation by Valproic Acid, 2010, pp.35, 1531~1540
50. Sakata, K., "Role of activity-dependent BDNF expression in hippocampal–prefrontal cortical regulation of behavioral perseverance", Proc. Natl. Acad. Sci. USA, 110, pp.15103~15108 (2013)
51. Bathina, S., "Brain-derived neurotrophic factor and its clinical implications", Arch. Med. Sci, 11, pp.1164~1178 (2015)
52. Nagahara, A. H., "Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice", J. Neurosci, 33, pp.15596~15602 (2013)
53. Wang, Z. H., "Deficiency in BDNF", TrkB neurotrophic activity stimulates δ-Secretase by upregulating C, Cell Rep, pp.2019, 28[DOI]
54. Gao, L., "Brain‑derived neurotrophic factor in Alzheimer’s disease and its pharmaceutical potential", Transl. Neurodegener, 11, pp.4~ (2022)
55. Juli Choi, "Hyperoxygenation Treatment Reduces Beta-amyloid Deposition via MeCP2-dependent Upregulation of MMP-2 and MMP-9 in the Hippocampus of Tg-APP", PS1 Mice, 2021, pp.30(4), 294~307[DOI]
56. Shaftel, S. S., "Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology", J. Clin. Invest, 117, pp.1595~1604 (2007)
57. Lee, D. C., "Review : experimental manipulations of microglia in mouse models of Alzheimer’s pathology : activation reduces amyloid but hastens tau pathology", Neuropathol. Appl. Neurobiol, 39, pp.69~85 (2013)
58. Kiyota, T., "AAV serotype 2", 1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice, 2012, pp.19, 724~733
59. Passamonti, L., "Neuroinflammation and functional connectivity in Alzheimer’s disease : interactive influences on cognitive performance", J. Neurosci, 39, pp.7218~7226 (2019)
60. Bradburn, S., "Neuroinflammation in mild cognitive impairment and Alzheimer’s disease : a meta-analysis", Ageing Res. Rev, 50, pp.1~8 (2019)

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