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Erratum : Elevated FBXL6 expression in hepatocytes activates VRK2-transketolase-ROS-mTOR-mediated immune evasion and liver cancer metastasis in mice

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주제분류생화학

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After online publication of this article, the authors noticed several errors in the “Results” section. The correct statement of this article should have read as below. In Fig. 1d, authors realize some inadvertent errors during image assembly, in which the upper panel image of Tsc1fl/fl; Alb-Cre mice is misused from another repeated experiment with similar result and the same conclusion but not from the 13 mice used in this study. In addition, the upper panel images of Fbxl6LSL-fl/+;Alb-Cre in Fig. 1d and Fig. S4a are erroneously copied. We sincerely apologize for this and now we would like to provide a new and more representative Fig. 1d as following, in which the Fig. 1d has been replaced. The correction of Fig. 1d does not influence the conclusion of the in vivo functionality experiments or the overall conclusion of the paper. In Fig. 2f, the authors regret that there are mistakes in labeling sequence of TKT peptide. “13-QALKDTA-21” is replaced with “13-QALKDTA-19” and “45-QALKDTA-53” is replaced with “45-QALKDTA-51”. The updated figure is provided below. This does not impact the analysis, results, or conclusions of the article. In Fig. 3a, the authors regret the labeling mistakes in sequence of TKT peptide. For Rat, “282-KKILVTPPQED-392”is changed to “314-KKILATPPQED-324.” For other species, “282-KKILATPPQED-392” is replaced with “282-KKILATPPQED-292”. The updated figure is provided below and do not impact the analysis, results, or conclusions of the article. In addition, authors realize that Fig. 5c had been assembled incorrectly, in which the mTOR band in Hepa1-6 cells is a longer exposure time mTOR band of Huh7. The correct mTOR band for Hepa1-6 has been updated and shown below. This correction does not influence the conclusion of the paper. These corrections do not alter the conclusions of this article. The authors apologize for any inconvenience caused. The original article has been corrected.

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Elevated FBXL6 expression in hepatocytes activates VRK2-transketolase-ROS-mTOR-mediated immune evasion and liver cancer metastasis in miceFang Lei, Lin Xiao-Tong, Luo Yuan-Deng, Wu Di, Xie Chuan-Ming, Yu Hong-Qiang, Zhang Jie, Zhang Yu-Jun생화학분자생물학회 · Experimental and Molecular Medicine2023 · 제55권 Reply to correspondence 1 on “MET promotes he patocellular carcinoma development through the promotion of TRIB3-mediated FOXO1 degradation”Many Sze Man Chan, Terence Kin Wah Lee대한간학회 · Clinical and Molecular Hepatology2026 · 제32권 제1호Correspondence to Editorial 2 on “MET promotes hepatocellular carcinoma development through the promotion of TRIB3-mediated FOXO1 degradation”Limin Xia, Tiantian Wang, Wenjie Huang대한간학회 · Clinical and Molecular Hepatology2026 · 제32권 제1호Antitumor Effect of Low-Dose of Rapamycin in a Transgenic Mouse Model of Liver Cancer김명수, 김준예, 김혜령, 노원상, 이형순, 주동진연세대학교의과대학 · Yonsei Medical Journal2022 · 제63권 제11호Reply to correspondence on “UBE2S: A novel driver of HIF-1alpha-induced metabolic reprogramming in hepatocellular carcinoma”Martina Mang Leng Lei, Terence Kin Wah Lee대한간학회 · Clinical and Molecular Hepatology2025 · 제31권 제1호Correspondence to editorial on “UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL”Ding Wei, Huijie Bian, Renyu Zhang, Zhinan Chen대한간학회 · Clinical and Molecular Hepatology2025 · 제31권 제1호

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