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대기오염 노출이 첫 출산아 저체중에 미치는 영향에 관한 연구 - 서울지역 1999년 ～ 2003년 출생코호트를 중심으로 -

Air Pollution Exposure and Low Birth Weight of Firstborn Fetus- A Birth Cohort Study in Seoul, 1999-2003 -

이종태|손지영|조용성
한국환경보건학회 (Korean Society of Environmental Health)|2007.08|한국환경보건학회지 (JOURNAL OF ENVIRONMENTAL HEALTH SCIENCES)|제33권 제4호|pp. 227-234

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참고문헌

초록

Abstract

Recent epidemiologic studies show that gestational exposure to air pollution adversely affects pregnancy outcomes including low birth weight in preterm birth. In this study, we evaluated the effect of air pollutants on LBW (low birth weight) on firstborn fetus throughout the gestational period using the birth cohort between 1999 and 2003 in Seoul. Using birth cohort data from the National Statistics Office of Korea we identified 288,346 firstborn births (excluded missing data on lack of information for birth weight and discordance between residential and certificated address from a total of 316,451) during 1999 to 2003 with complete covariate (gender, parity, date of birth, gestational age, parental age and educational level, maternal occupation etc.) and maternal residential history data. Our subjects were defined as more than 37 weeks and less than 44 weeks of completed gestation and we identified 5,457 persons (1.89%) by low birth weight (<2.5 kg) in this study. Using logistic regression, we estimated the risk of mean (entire pregnancy and trimester period) air pollution concentrations for CO, O3, PM10, NO2 and SO2. In terms of trimester-specific exposure, we found that some air pollutants exposure in each trimester would increase the risk for LBW. Results also showed that the effect size of air pollutants exposure during the first and third trimester is higher than during the second trimester. In all trimester, the estimated risk of LBW was 1.831 (95% CI=1.573-2.132) with unit increase for CO, 1.139 (95% CI=1.107-1.172) for SO2 and 1.009 (95% CI=1.001-1.017) for O3. Our results suggest that exposure during the gestation period to relatively low levels of some air pollutants may be associated with a reduction in birth weight on firstborn fetus. These findings implicate the effective risk management strategies should be applied to minimize the public health impacts for pregnant women.

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관련 논문AI추천

2002년 서울시 대기오염과 출생 자료를 이용한 저체중아 환경보건감시체계 연구김병미, 김영주, 김옥진, 박혜숙, 서주희, 임종한, 하은희, 홍윤철대한예방의학회 · 예방의학회지2007 · 제40권 제5호대기오염 노출이 출산시 태아에 미치는 건강영향김영주, 박은애, 박혜숙, 이보은, 하은희, 홍윤철대한예방의학회 · 예방의학회지2004 · 제37권 제4호Prenatal Exposure to PM10 and Preterm Birth between 1998 and 2000 in Seoul, Korea김호, Bo-Eun Lee, Eun-Ae Park, Eun-Hee Ha, Hye-Sook Park, Young-Ju Kim, Yun-Chul Hong, Yun-Sang Kim대한예방의학회 · 예방의학회지2004 · 제37권 제4호Short-term Associations of Air Pollution with Postneonatal Infant Death in Seoul, Korea, 1999-2003손지영, 이종태, 조용성한국환경보건학회 · 한국환경보건학회지2008 · 제34권 제5호임산부 간접흡연과 저체중아 및 조산아 출생에 관한 코호트 연구강중구, 김상훈, 김영주, 김정연, 김주오, 박혜숙, 이보은, 이종태, 하은희, ？윤철대한예방의학회 · 예방의학회지2003 · 제36권 제2호Decreased birth weight after prenatal exposure to wildfires on the eastern coast of Korea in 2000김종헌, 임아영, Jung En-Joo한국역학회 · Epidemiology and Health2023 · 제45권

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