울산지역 대기오염과 알레르기 비염 유병률과의 관계
An Association Between Air Pollution and the Prevalence of Allergic Rhinitis in the Ulsan Metropolitan Region
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초록
This study aims to investigate the relationship between air pollution exposure and the prevalence of allergic rhinitis in a young population in the Ulsan metropolitan region (UMR). Data on physician-diagnosed allergic rhinitis (past 12months) in 1,449 infants and children aged 1-18 years who lived within 1.5 or 2 km of air quality monitoring sites were collected in a cross-sectional health interview survey conducted between January-February 2006 in the UMR. Comparisons of the spatial distribution of the prevalence rates for allergic rhinitis and annual average pollutant concentrations over the region showed that a relatively high prevalence rate occurred around the coastal industrial area, with high PM10concentrations. A linear correlation analysis demonstrated a positive correlation relationship between them (R = 0.680,p = 0.04). Multiple linear regression analysis revealed that the combined effect of the PM10 and SO2 variables accounts for approximately 81% of the variance (R-square: 0.81) in the prevalence rate. From the multiple logistic regression analysis after adjustment by age, sex, and air-pollutant factors, the PM10 and SO2 which were mainly from industrialrelated emissions were found to be significantly associated with an increased risk of allergic rhinitis (aOR: 1.76, 95%CI: 1.15-2.70 for PM10 ; aOR: 1.63, 95% CI: 1.12-2.35 for SO2).
Abstract
This study aims to investigate the relationship between air pollution exposure and the prevalence of allergic rhinitis in a young population in the Ulsan metropolitan region (UMR). Data on physician-diagnosed allergic rhinitis (past 12months) in 1,449 infants and children aged 1-18 years who lived within 1.5 or 2 km of air quality monitoring sites were collected in a cross-sectional health interview survey conducted between January-February 2006 in the UMR. Comparisons of the spatial distribution of the prevalence rates for allergic rhinitis and annual average pollutant concentrations over the region showed that a relatively high prevalence rate occurred around the coastal industrial area, with high PM10concentrations. A linear correlation analysis demonstrated a positive correlation relationship between them (R = 0.680,p = 0.04). Multiple linear regression analysis revealed that the combined effect of the PM10 and SO2 variables accounts for approximately 81% of the variance (R-square: 0.81) in the prevalence rate. From the multiple logistic regression analysis after adjustment by age, sex, and air-pollutant factors, the PM10 and SO2 which were mainly from industrialrelated emissions were found to be significantly associated with an increased risk of allergic rhinitis (aOR: 1.76, 95%CI: 1.15-2.70 for PM10 ; aOR: 1.63, 95% CI: 1.12-2.35 for SO2).
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