Effect on Testosterone Production in Sprague-Dawley Rats of Gastrodia and Bee Pollen
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Objectives: We investigated the effects of Korean gastrodia and bee pollen on testosterone production in Sprague-Dawley rats. Methods: This study measured the body weight, consumption of food and water, and serum testosterone concentration in SD rats fed for four weeks with gastrodia and bee pollen. Results: The average body weights after four weeks were 375±2 g for the control group, 358±3 g for gastrodia consumption, and 354±2 g and 367±8 g for acorn pollen and Siberian gooseberry pollen, respectively. The average food consumption in SD rats over the four weeks in the control was 23.6 g for gastrodia consumption,24.3 g and 24.9 g for acorn pollen and Siberian gooseberry pollen, respectively. The average water consumption over the four weeks was 38.33 ml in the control group, 35.0 ml for gastrodia treatment, and 33.3 ml and 33.3 ml for acorn pollen and Siberian gooseberry pollen treatment, respectively. The testosterone secretion levels in the serum of male rats were increased by gastrodia, acorn pollen, and Siberian gooseberry pollen (2.68, 3.00, and 3.28 pg/ml, respectively) compared to the control group (2.23 pg/ml). Conclusions: These results suggest that gastrodia or bee pollen may be developed as a complementary medicine to improve sexual hormone production.
Abstract
Objectives: We investigated the effects of Korean gastrodia and bee pollen on testosterone production in Sprague-Dawley rats. Methods: This study measured the body weight, consumption of food and water, and serum testosterone concentration in SD rats fed for four weeks with gastrodia and bee pollen. Results: The average body weights after four weeks were 375±2 g for the control group, 358±3 g for gastrodia consumption, and 354±2 g and 367±8 g for acorn pollen and Siberian gooseberry pollen, respectively. The average food consumption in SD rats over the four weeks in the control was 23.6 g for gastrodia consumption,24.3 g and 24.9 g for acorn pollen and Siberian gooseberry pollen, respectively. The average water consumption over the four weeks was 38.33 ml in the control group, 35.0 ml for gastrodia treatment, and 33.3 ml and 33.3 ml for acorn pollen and Siberian gooseberry pollen treatment, respectively. The testosterone secretion levels in the serum of male rats were increased by gastrodia, acorn pollen, and Siberian gooseberry pollen (2.68, 3.00, and 3.28 pg/ml, respectively) compared to the control group (2.23 pg/ml). Conclusions: These results suggest that gastrodia or bee pollen may be developed as a complementary medicine to improve sexual hormone production.
참고문헌 (16)
- Saez JM., "Leydig cells: endocrine, paracrine and autocrine regulation", Endocr Rev, pp.574~626 (1994)
- Sinclair S, "Male infertility: nutritional and environmental considerations", Altern Med Rev, pp.28~38 (2000)
- Roscoe WA, "Failure of spermatogenesis in mice lacking connexin 43", Biol Reprod, pp.829~838 (1994)
- Huff DS, "Hormonal therapy for the subfertility of cryptorchidism", Horm Res, pp.38~40 (2001)
- Crimmel AS, "Withered Yang: a review of traditional Chinese medical treatment of male infertility and erectile dysfunction", J Androl, pp.173~182 (2001)
- Kang Sun Ryu, "Testosterone Secretion Effect according to the Growth Stage of Silkworm (Bombyx mori L.)", International Journal of Industrial Entomology, 20(2), pp.75~77 (2010), 한국잠사학회
- Kang-Sun Ryu, "Secretion Effect of Estrogen of Different Growth Stages of Silkworm (Bombyx mori L.)", International Journal of Industrial Entomology, 22(1), pp.17~20 (2011), 한국잠사학회
- 홍인표, "밀리타리스동충하초가 테스토스테론 형성에 미치는 영향", 한국균학회지, 39(2), pp.148~150 (2011), 한국균학회
- Hsu CC, "In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells", Life Sci, 73, pp.2127~2136 (2003)
- Silva TMS, "Chemical composition and free radical scavenging activity of pollen loads from stingless bee Melipona subnitida Ducke", J Food Compos Anal, 19, pp.507~511 (2006)
- Liu CL, "Determination of Gastrodin, p-Hydroxybenzyl Alcohol,Vanillyl Alcohol, p-Hydroxylbenzaldehyde and Vanillin in Tall Gastrodia Tuber by High-Performance Liquid Chromatography", Chromatographla, 55, pp.317~320 (2002)
- Tomas-Lorente F, "Flavonoids from Cistus- Ladanifer bee pollen", Phytochemistry, 1, pp.2027~2029 (1992)
- Ukiya M, "Isolation, structural elucidation, and inhibitory effects of terpenoid and lipid constituents from sunflower pollen on Epstein-Barr virus early antigen induced by tumor promoter,(.) TPA", J Agric Food Chem, 51, pp.2949~2957 (2003)
- Sheen L, "Antidepressant effects of Gastrodia elata Bl. at the genomic level", BMC Complementary and Alternative Medicine, 12(1), pp.35~ (2012)
- Melita SK, "Sex hormones and corticosteroids in pollen of Pinus nigra", Phytochemistry, 18(2), pp.345~346 (1979)
- Bahmanpour S, "Effect of Phoenix Dactylifera Pollen on Sperm Parameters and Reproductive system of Adult Male Rats", Iran J Med Sci, 31(4), pp.208~212 (2006)