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논문

가습기 살균제 노출 및 건강피해 규모 평가 연구

Population Size Estimates for the Use of Humidifier Disinfectants and Experience of Health Effects from Exposure to Humidifier Disinfectants

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참고문헌

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초록

Objective: This study was performed to estimate the number of those who used humidifier disinfectants (HDs) and experienced health effects from exposure to HDs in Korea between 1994 and 2011. Methods: A nationwide interview survey was conducted for the representative sample to identify the proportion of those who used HDs among the general population (n=3,001). Another online survey was conducted for those exposed to HDs to find the proportion of those who experienced health effects among those who were exposed to HDs (n=3,993). Statistics for population size by region and year (1994-2011) were used to estimate the cumulative number of those exposed to HDs and those who experienced health effects. In terms of the proportion of those exposed to HDs, those less than 30 years of age were excluded due to an issue related to information bias. Various approaches for estimation included the capture-recapture method for estimation of those who experienced health effects. Results: The cumulative proportion of those exposed to HDs was 6.7% among the general population, and the proportion of those who experienced health effects among those who were exposed to HDs was 13.9%. Based on these factors, it was estimated that 3.5 to 4.0 million people were exposed to HDs and 350 to 400 thousand experienced health effects at least requiring visiting a hospital. Conclusion: It is suggested that a nationwide representative sample may be essential for population size estimation of those exposed to environmental risk factors and of those who experienced health effects.

Abstract

Objective: This study was performed to estimate the number of those who used humidifier disinfectants (HDs) and experienced health effects from exposure to HDs in Korea between 1994 and 2011. Methods: A nationwide interview survey was conducted for the representative sample to identify the proportion of those who used HDs among the general population (n=3,001). Another online survey was conducted for those exposed to HDs to find the proportion of those who experienced health effects among those who were exposed to HDs (n=3,993). Statistics for population size by region and year (1994-2011) were used to estimate the cumulative number of those exposed to HDs and those who experienced health effects. In terms of the proportion of those exposed to HDs, those less than 30 years of age were excluded due to an issue related to information bias. Various approaches for estimation included the capture-recapture method for estimation of those who experienced health effects. Results: The cumulative proportion of those exposed to HDs was 6.7% among the general population, and the proportion of those who experienced health effects among those who were exposed to HDs was 13.9%. Based on these factors, it was estimated that 3.5 to 4.0 million people were exposed to HDs and 350 to 400 thousand experienced health effects at least requiring visiting a hospital. Conclusion: It is suggested that a nationwide representative sample may be essential for population size estimation of those exposed to environmental risk factors and of those who experienced health effects.

참고문헌 (14)

  1. Korea Environmental Industry & Technology Institute, "Comprehensive portal for humidifier disinfectant damage support: Statistics", ~ (2019)
  2. 박동욱, "가습기 살균제 건강 피해 조사에서 노출 평가 방법 고찰", 한국환경보건학회지, 44(2), pp.107~114 (2018), 한국환경보건학회
  3. 전병학, "Frequency of Humidifier and Humidifier Disinfectant Usage in Gyeonggi Provine", 환경독성보건학회지, 27, pp.1~4 (2012), 환경독성보건학회
  4. Moon-Hee Chang, "Characteristics of Humidifier Use in Korean Pregnant Women: The Mothers and Children’s Environmental Health (MOCEH) Study", 환경독성보건학회지, 27, pp.1~4 (2012), 환경독성보건학회
  5. Lung Injury Investigation Committee by the Korean Center for Disease Control, "White paper on health damage by the exposure to humidifier disinfectant", ~ (2014)
  6. Park DU, "Relationship between Exposure to Household Humidifier Disinfectants and Risk of Lung Injury: A Family-Based Study", PLoS One, 10(5), pp.e0124610~ (2015)
  7. Yang HJ, "Inhalation toxicity of humidifier disinfectants as a risk factor of children’s interstitial lung disease in Korea: a case-control study", PLoS One, 8(6), pp.e64430~ (2013)
  8. Paek D, "Nationwide Study of Humidifier Disinfectant Lung Injury in South Korea, 1994-2011. Incidence and Dose-Response Relationships", Ann Am Thorac Soc, 12(12), pp.1813~1821 (2015)
  9. "Humidifier disinfectants, one-tenth intent to purchase again" (2011)[URL]
  10. "One-fifth of nation are potential victim by the exposure to humidifier disinfectant" (2016)[URL]
  11. "Establishing disease identification and standards criteria to expand the range of health hazards caused by the humidifier sterilizer. (NIER-SP2016-429)"[URL]
  12. 최예용, "가습기살균제 참사의 진행과 교훈(Q&A)", 한국환경보건학회지, 43(1), pp.1~22 (2017), 한국환경보건학회
  13. "Central Population Resisters by year: 1994-2011"[URL]
  14. MN Ha, "Completeness Estimation of the Korean Medical Insurance Data in Childhood Asthma: Using Capture-Recapture Method", J Prev Med Public Health, 30(2), pp.428~439 (1997)

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