PM10과 오존이 연령군별 천식 입원에 미치는 영향
Age dependencies in air pollution-associated asthma hospitalization
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참고문헌
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초록
This study investigated the age dependencies on ambient air pollution-associated asthma hospitalization in Seoul in 2003-2005. For all ages and the age groups of 0-14, 15-64, and 65+years, the Generalized Additive Model (GAM) was used to estimate the relative risk of daily asthma hospitalization associated with changes in particulate matter and ozone. The time-trends, seasonal variances, day effects, temperature, humidity, and pressure at sea level were controlled in the models. Significant associations were observed between asthma hospitalization and the levels of PM10, and O₃. The relative risks (RRs) of asthma hospitalization for every 10 unit increases in PM10(㎍/m³) and O3(ppb) were 1.008 (95% CI 1.005-1.012), and 1.012 (95% CI 1.003-1.020), respectively. Evaluated over 10㎍/m³ increase in PM10, we found the relative risks of asthma hospitalization to be 1.009 (95% CI 1.004-1.014) in 0-14 age group, and 1.015 (95% CI 1.008-1.022) in 65+ age group. Considering 10 ppb increase in O3, those were 1.012 (95% CI 1.003-1.020) in 0-14 age group, and 1.025 (95% CI 1.09-1.041) in 65+ age group. It was concluded that current levels of ambient air pollution in Seoul make a significant contribution to the variation in daily asthma hospitalization. Further reduction in air pollution is necessary to protect the health of the community, especially that of the higher risky groups including children and elderly population.
Abstract
This study investigated the age dependencies on ambient air pollution-associated asthma hospitalization in Seoul in 2003-2005. For all ages and the age groups of 0-14, 15-64, and 65+years, the Generalized Additive Model (GAM) was used to estimate the relative risk of daily asthma hospitalization associated with changes in particulate matter and ozone. The time-trends, seasonal variances, day effects, temperature, humidity, and pressure at sea level were controlled in the models. Significant associations were observed between asthma hospitalization and the levels of PM10, and O₃. The relative risks (RRs) of asthma hospitalization for every 10 unit increases in PM10(㎍/m³) and O3(ppb) were 1.008 (95% CI 1.005-1.012), and 1.012 (95% CI 1.003-1.020), respectively. Evaluated over 10㎍/m³ increase in PM10, we found the relative risks of asthma hospitalization to be 1.009 (95% CI 1.004-1.014) in 0-14 age group, and 1.015 (95% CI 1.008-1.022) in 65+ age group. Considering 10 ppb increase in O3, those were 1.012 (95% CI 1.003-1.020) in 0-14 age group, and 1.025 (95% CI 1.09-1.041) in 65+ age group. It was concluded that current levels of ambient air pollution in Seoul make a significant contribution to the variation in daily asthma hospitalization. Further reduction in air pollution is necessary to protect the health of the community, especially that of the higher risky groups including children and elderly population.
참고문헌 (27)
- Dominici, F., "Revised analyses of the National Morbidity, Mortality, and Air Pollution Study: mortality among residents of 90 cities", Journal of Toxicology and Environmental Health, 68(13-14), pp.1071~1092 (2005)
- Katsouyanni, K., "Short term effects of ambient sulphur dioxide and particulate matter on mortality in 12 European cities : results from time series data from the APHEA project", Brtish Medical Journal, 314, pp.1658~1663 (1997)
- 이종태, "메타분석을 적용한 전국 7개 대도시의 대기오염과 일일사망발생의 상관성 연구(1998년～2001년)", 한국환경보건학회지, 32(4), pp.304~315 (2006), 한국환경보건학회
- Wellenius, G. A., "Particulate air pollution and hospital admissions for congestive heart failure in seven United States cities", The American Journal of Cardiology, 97, pp.404~408 (2006)
- Lin, M., "The influence of ambient coarse particulate matter on asthma hospitalization in children: case-crossover and time-series analyses", Environmental Health Perspectives, 110, pp.575~581 (2002)
- Zanobetti, A., "Air pollution and emergency admissions in Boston, MA", Journal of Epidemiology and Community Health, 60, pp.890~895 (2006)
- Peel, J. L., "Ambient air pollution and respiratory emergency department visits", Epidemiology, 16, pp.164~174 (2005)
- 이종태, "대기오염 노출이 첫 출산아 저체중에 미치는 영향에 관한 연구 - 서울지역 1999년 ～ 2003년 출생코호트를 중심으로 -", 한국환경보건학회지, 33(4), pp.227~234 (2007), 한국환경보건학회
- 유승도, "미세먼지가 울산지역 초등학생의 폐기능에 미치는 영향", 한국환경보건학회지, 33(5), pp.365~371 (2007), 한국환경보건학회
- 박춘선, "건강보험 청구자료를 이용한 우리나라 천식환자의 질병비용부담 추계", 예방의학회지, 39(5), pp.397~403 (2006), 대한예방의학회
- World Health Organization, "Preventing disease through healthy environments", ~ (2006)
- Atkinson, R. W., "Acute effects of particulate air pollution on respiratory admissions: results from APHEA 2 project. Air Pollution and Health: a European Approach", American Journal of Respiratory and Critical Care Medicine, 164, pp.1860~1866 (2001)
- Schwartz, J., "Particulate air pollution and hospital emergency room visits for asthma in Seattle", The American Review of Respiratory Disease, 147(4), pp.826~831 (1993)
- Lee, J. T., "Air pollution and asthma among children in Seoul, Korea", Epidemiology, 13, pp.481~484 (2002)
- Lee, J. T., "Association between Air Pollution and Asthma-related Hospital Admissions in Children Seoul, Korea : A Case-crossover Study", Journal of Preventive Medicine and Public Health, 36(1), pp.47~53 (2003)
- 손지영, "사회경제수준에 따른 오존과 소아천식 관련 입원의 상관성 연구", 예방의학회지, 39(1), pp.81~86 (2006), 대한예방의학회
- Kim, Y. K., "High prevalence of current asthma and active smoking effect among the elderly", Clinical and Experimental Allergy, 32, pp.1706~1712 (2002)
- Parameswaran, K., "Asthma in the elderly: underperceived, underdiagnosed and undertreated; a community survey", Respiratory Medicine, 92, pp.573~577 (1998)
- Enright, P. L., "Underdiagnosis and undertreatment of ashtma in the elderly", Cardiovascular Health Study Research Group, 116, pp.603~613 (1999)
- Ko, F. W., "12-year change in prevalence of respiratory symptoms in elderly Chinese living in Hong Kong", Respiratory Medicine, 100, pp.1598~1607 (2006)
- Pope, C. A. III., "Synoptic Weather Modeling and Estimates of the Exposure-Response Relationship between Daily Mortality and Particulate Air Pollution", Environmental Health Perspectives, 104, pp.414~420 (1996)
- Akaike, K., "Information theory and an extension of the maximum likehood principle", ~ (1973)
- Dominici, F., "On the use of generalized additive models in time-series studies of air pollution and health", The American Journal of Epidemiology, 156, pp.193~203 (2002)
- Kim, J. Y., "Changes in ambulatory care service consumption after the separation of prescribing and dispensing : Analysis with the episode of care and the continuity of care", pp.2003
- Anderson, H. R., "Air pollution, pollens, and daily admissions for asthma in London 1987-92", Thorax, 53, pp.842~848 (1998)
- 김선영, "서울지역 대기오염이 천식에 미치는 급성영향 : 연구대상의 특성에 따른 비교", 예방의학회지, 39(4), pp.309~316 (2006), 대한예방의학회
- Korea National Statistical Office, "Population projections results", ~ (2007)