대학생들의 혈액 내 휘발성 유기화합물 노출에 영향을 미치는 요인
Determinant Factors for Blood VOCs Exposures in College Students
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objectives: The objective of this study was to identify determine factors for blood VOCs levels in collegestudents. Methods: Venous blood samples were collected from healthy 29 male and 25 female volunteers. The sampleswere analyzed with solid-phase microextraction gas chromatography and mass spectrometry. Results: Blood concentrations of benzene, toluene, ethylbenzene, m-,p-xylene, o-xylene were higher in smokinggroup than in non-smoking group. Geometric means of smoking group and non-smoking group were 0.45 and0.36 μg/L in benzene, 0.82 and 0.47 μg/L in toluene, 0.44 and 0.41 μg/L in ethylbenzene, 0.49 and 0.39 μg/Lin m-,p-xylene and 0.47 and 0.43 μg/L in o-xylene, respectively. Gender, alcohol drinking, coffee, commutingtime (30 minutes) by a car and adjacency between home and road were not associated with increasing bloodVOCs concentrations of college students. Conclusion: Smoking habit was significantly associated with blood concentrations of benzene, toluene,ethylbenzene, o-,m-,p-xylene in college students.
Abstract
Objectives: The objective of this study was to identify determine factors for blood VOCs levels in collegestudents. Methods: Venous blood samples were collected from healthy 29 male and 25 female volunteers. The sampleswere analyzed with solid-phase microextraction gas chromatography and mass spectrometry. Results: Blood concentrations of benzene, toluene, ethylbenzene, m-,p-xylene, o-xylene were higher in smokinggroup than in non-smoking group. Geometric means of smoking group and non-smoking group were 0.45 and0.36 μg/L in benzene, 0.82 and 0.47 μg/L in toluene, 0.44 and 0.41 μg/L in ethylbenzene, 0.49 and 0.39 μg/Lin m-,p-xylene and 0.47 and 0.43 μg/L in o-xylene, respectively. Gender, alcohol drinking, coffee, commutingtime (30 minutes) by a car and adjacency between home and road were not associated with increasing bloodVOCs concentrations of college students. Conclusion: Smoking habit was significantly associated with blood concentrations of benzene, toluene,ethylbenzene, o-,m-,p-xylene in college students.
참고문헌 (14)
- Moon C-S, "Use of solvents in industries in Korea: experience in Sinpyeong-Jangrim industrial complex", Int Arch Occup Environ Health, 74(2), pp.148~152 (2001)
- 황윤형, "연구참여자에 의한 주택실내 휘발성 유기화합물 농도의 측정", 한국환경보건학회지, 37(5), pp.369~375 (2011), 한국환경보건학회
- Ha CH., "A study on volatile organic compounds (VOC) in environmental tobacco smoke (ETS) at indoor office environments", Korean J Environ Health Soc, 27(3), pp.87~98 (2001)
- 김대선, "비산단지역 환경오염 수준 및 주민의 생체지표 모니터링", 한국환경보건학회지, 38(6), pp.482~492 (2012), 한국환경보건학회[DOI]
- 이치원, "공단지역 일부 주민들의 주택유형 및 실내", 외에 따른 VOCs(Benzene, Toluene, Xylene) 농도 및 상관성에 관한 연구, 2010, pp.36(5), 351~359[DOI]
- 문찬석, "일부 대학생들의 카드뮴과 납 섭취량 및 체내부하", 한국산업보건학회지, 21(1), pp.25~32 (2011), 한국산업보건학회
- Korea Centers for Disease Control and Prevention., (2012), Korea Centers for Disease Control and Prevention Press
- Ikeda M., "Solvents in urine as exposure markers", Toxicol Lett, 108, pp.99~106 (1999)
- Kawai T, "Crivi-linear relation between acetone in breathin air and acetone in urine among workers exposed to acetone vapor", Toxicol Lett, 62, pp.85~91 (1993)
- Kawai T, "Comparative evaluation of blood and urine analysis as a tool for biological monitoring of n-hexane and toluene", Int Arch Occup Environ Health, 65, pp.S123~S126 (1993)
- National Institute of Environmental Research., "Development and standardize of analytical method of environmental pollutants in body fluids II" (2013), National Institute of Environmental Research Press
- Chambers DM, "Impact of cigarette smoking on Volatile Organic Compound (VOC) blood levels in the U.S. Population: NHANES 2003-2004", Environ Int, 37, pp.1321~1328 (2011)
- Lin YS, "Relationships between levels of volatile organic compounds in air and blood from the general population", J Expo Sci Environ Epidemiol, 18(4), pp.421~429 (2008)
- Ashley DL, "Measurement of volatile organic compounds in human blood", Environ Health Perspect, 104(5), pp.871~877 (1996)