Comparison of Group A, B and C Rotaviral Gastroenteritis among Children in Korea: Prevalence and Clinical Features
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Purpose: The aim of this study is that the prevalence of rotavirus infection was evaluated by each group and clinical featuresof group A, B and C rotaviruses infections were described respectively to compare one with another. Methods: Between January 2010 and December 2010, we enrolled a group of children below 10 years of age admittedfor management of acute diarrhea at the Catholic University of Korea Bucheon St. Mary's Hospital. A total of 310 stoolsamples documented to be free of common bacterial pathogens were collected from children with diarrhea. The presenceof group A, B or C rotavirus is indicated by amplification of DNA segments of the expected lengths after the first andsecond PCRsResults: In a total of 310 stool specimens, 40 (12.9%) specimens were positive for rotaviruses. These included 23 (7.4%)positive for group A, 5 (1.6%) for group B and 12 (3.9%) for group C rotaviruses. Group B rotavirus infected patients hadsignificantly less diarrheas per day (group A: P =0.01, group C: P =0.01) and shorter duration of vomiting days (group A:P =0.03, group C: P =0.03) than those with group A and C rotaviruses infection respectively. All the group B rotaviruseshad been isolated in March and October. Group C rotavirus infections were prevalent during late summer and early winterand peaked in October. Conclusion: These findings indicate that group B and C rotaviruses are notable causes or the contributing causes of diarrheaamong infants and children in Korea.
Abstract
Purpose: The aim of this study is that the prevalence of rotavirus infection was evaluated by each group and clinical featuresof group A, B and C rotaviruses infections were described respectively to compare one with another. Methods: Between January 2010 and December 2010, we enrolled a group of children below 10 years of age admittedfor management of acute diarrhea at the Catholic University of Korea Bucheon St. Mary's Hospital. A total of 310 stoolsamples documented to be free of common bacterial pathogens were collected from children with diarrhea. The presenceof group A, B or C rotavirus is indicated by amplification of DNA segments of the expected lengths after the first andsecond PCRsResults: In a total of 310 stool specimens, 40 (12.9%) specimens were positive for rotaviruses. These included 23 (7.4%)positive for group A, 5 (1.6%) for group B and 12 (3.9%) for group C rotaviruses. Group B rotavirus infected patients hadsignificantly less diarrheas per day (group A: P =0.01, group C: P =0.01) and shorter duration of vomiting days (group A:P =0.03, group C: P =0.03) than those with group A and C rotaviruses infection respectively. All the group B rotaviruseshad been isolated in March and October. Group C rotavirus infections were prevalent during late summer and early winterand peaked in October. Conclusion: These findings indicate that group B and C rotaviruses are notable causes or the contributing causes of diarrheaamong infants and children in Korea.
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