Brachial Artery Thrombosis in an 8-year-old Boy with Antiphospholipid Antibodies Induced by Mycoplasma pneumoniae Infection: a Case Report
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Antiphospholipid antibodies may be produced in cases involving autoimmune diseases and can sometimes be caused by infections, such as Mycoplasma pneumoniae infection. However, antiphospholipid antibodies causing thrombosis associated with M. pneumoniae pneumonia in children have rarely been reported. We report a case of an 8-year-old boy with M. pneumoniae pneumonia with antiphospholipid antibodies, complicated by brachial artery thrombosis. He was found to have antiphospholipid antibodies and low protein S levels. The brachial artery thrombus was removed via thrombectomy. The titers of antiphospholipid antibodies turned normal within 5 months. This is a rare case of M. pneumoniae infection with brachial artery thrombosis associated with transient antiphospholipid antibodies.
Abstract
Antiphospholipid antibodies may be produced in cases involving autoimmune diseases and can sometimes be caused by infections, such as Mycoplasma pneumoniae infection. However, antiphospholipid antibodies causing thrombosis associated with M. pneumoniae pneumonia in children have rarely been reported. We report a case of an 8-year-old boy with M. pneumoniae pneumonia with antiphospholipid antibodies, complicated by brachial artery thrombosis. He was found to have antiphospholipid antibodies and low protein S levels. The brachial artery thrombus was removed via thrombectomy. The titers of antiphospholipid antibodies turned normal within 5 months. This is a rare case of M. pneumoniae infection with brachial artery thrombosis associated with transient antiphospholipid antibodies.
참고문헌 (15)
- Tripodi A, "Antiphospholipid syndrome: laboratory detection, mechanisms of action and treatment", J Intern Med, 270, pp.110~122 (2011)
- Asherson RA, "Antiphospholipid antibodies and infections", Ann Rheum Dis, 62, pp.388~393 (2003)
- Bakshi M, "ycoplasma pneumonia with antiphospholipid antibodies and a cardiac thrombus", Lupus, 15, pp.105~106 (2006)
- Defilippi A, "Epidemiology and clinical features of Mycoplasma pneumoniae infection in children", Respir Med, 102, pp.1762~1768 (2008)
- Jain S, "Community-acquired pneumonia requiring hospitalization among U.S", children. N Engl J Med, 372, pp.835~845 (2015)
- Ruiz-Irastorza G, "Antiphospholipid syndrome", Lancet, 376, pp.1498~1509 (2010)
- Comarmond C, "Antiphospholipid syndrome: from pathogenesis to novel immunomodulatory therapies", Autoimmun Rev, 12, pp.752~757 (2013)
- Witmer CM, "Mycoplasma pneumoniae, splenic infarct, and transient antiphospholipid antibodies: a new association?", Pediatrics, 119, pp.e292~295 (2007)
- Graw-Panzer KD, "Venous thrombosis and pulmonary embolism in a child with pneumonia due to Mycoplasma pneumoniae", J Natl Med Assoc, 101, pp.956~958 (2009)
- Waites KB, "Mycoplasma pneumoniae and its role as a human pathogen", Clin Microbiol Rev, 17, pp.697~728 (2004)
- Narita M, "Pathogenesis of extrapulmonary manifestations of Mycoplasma pneumoniae infection with special reference to pneumonia", J Infect Chemother, 16, pp.162~169 (2010)
- Youn YS, "Difference of clinical features in childhood Mycoplasma pneumoniae pneumonia", BMC Pediatr, 10, pp.48~ (2010)
- Padovan CS, "Detection of Mycoplasma pneumoniae DNA in cerebrospinal fluid of a patient with M. pneumoniae infection-“associated” stroke", Clin Infect Dis, 33, pp.E119~121 (2001)
- Khamashta MA, "The management of thrombosis in the antiphospholipid-antibody syndrome", N Engl J Med, 332, pp.993~997 (1995)
- Flateau C, "Aortic thrombus and multiple embolisms during a Mycoplasma pneumoniae infection", Infection, 41, pp.867~873 (2013)