국내 홍역, 유행성이하선염 및 풍진 백신 접종 후 연령에 따른 항체양성율 변화
The Change of IgG Antibody Titer to Measles, Mumps and Rubella According to Age
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목 적:홍역, 유행성이하선염 및 풍진 예방접종 시행 후 연령 증가에 따른 항체양성율의 변화를 조사한다. 방 법:병원에 내원한 7-20세의 환아를 대상으로 잔여 혈청을 이용하여 IgG 항체를 검사하였다. 결 과:총 408례 중 홍역은 275례로 67.4%, 유행성이하선염은 112례로 27.5%, 풍진은 367례로 90.0%의 양성율을 보였다. 양성자의 IgG 수치는 각각 2.77±1.18 Index, 2.08±1.29 Index 및 60.46±63.47 IU/mL 이었다. 결 론:홍역 67.4%, 유행성이하선염 27.5% 및 풍진 90.0%의 IgG 항체 양성율을 보였다. 홍역, 유행성이하선염 및 풍진의 유행을 막기 위해서는 높은 접종율의 유지가 중요하며, 또한 보호자에 대한 접종기록 등의 관리가 중요할 것으로 생각된다.
Abstract
Purpose:We investigated the change of antibody titer to measles, mumps and rubella according to age after vaccination. Methods:The IgG antibody titers to measles, mumps and rubella were tested on the residual serum from patients aged 7-20 years old after routine laboratory testing in the hospital with informed consent from the parents. Results:Antibody to measles was present in 275 cases out of 408 cases with a positive rate of 67.4%, the mean IgG titer was 2.77±1.18 Index. Antibody to mumps was present in 112 cases out of 408 cases with a positive rate of 27.5%, the mean IgG titer was 2.08±1.29 Index. Antibody to rubella was present in 367 cases out of 408 cases with a positive rate of 90.0%, the mean IgG titer was 60.46±63.47 IU/mL. Conclusion:It is important to maintain a high rate of vaccination coverage in order to prevent an outbreak of measles, mumps, or rubella. It is also important to stress the maintenance of vaccination records for further reference.
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