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Successful Treatment of Vancomycin-Resistant Enterococcus Bacteremia With a Combination of Daptomycin and Tigecycline in an Infant who Underwent Heart-Lung Transplantation

Park Su Eun|Kang Jeong Eun|Byun Joung-Hee|Kim Younga
대한소아감염학회 (The Korean Society of Pediatric Infectious Diseases)|2022.09|Pediatric Infection and Vaccine|제29권 제2호|pp. 105-109|DOI 10.14776/piv.2022.29.e11

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참고문헌

키워드

VancomycinTigecyclineBacteremiaEnterococcus faeciumDaptomycin

초록

다제내성 반코마이신 저항성 장내구균(multidrug-resistant vancomycin-resistant enterococci, VRE)에 의한 침습감염의 치료는 특히 기저질환을 가진 소아 환자들에게 어려운 점이 있다. 소아환자들에게서 VRE 감염을 치료하기 위한 새로운 항생제에 대한 연구가 충분히 이루어지지 않았다. 본 증례는 심폐이식을 받은 생후 6개월 된 영아에서 linezolid 중단 이후 재발된 VRE 균혈증에 대해 daptomycin과 tigecycline 조합으로 성공적으로 치료하여 이를 보고하는 바이다.

Abstract

The treatment of invasive infections caused by multidrug-resistant vancomycin-resistant enterococci (VRE) is challenging, particularly in pediatric patients with underlying medical conditions. Newer antibiotics used to treat VRE infections in pediatric patients are insufficiently studied. This report presents the case of a 6-month-old infant who underwent heart–lung transplantation and was successfully treated with a combination of daptomycin and tigecycline for recurrent VRE bacteremia shortly after the discontinuation of linezolid.

참고문헌 (12)

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관련 논문AI추천

신생아에서 Vancomycin 내성 장구균 감염 1례강진무, 김천수, 김홍식, 배수정, 이상락, 최귀전대한소아감염학회 · Pediatric Infection and Vaccine1999 · 제6권 제2호단일 기관에서 소아 환자들의 임상검체로부터 분리된 Vancomycin 내성 장구균에 대한 임상적 고찰김기주, 김기환, 김동수, 박여훈, 박은숙, 이택진, 전진경대한소아감염학회 · Pediatric Infection and Vaccine2007 · 제14권 제2호지속성 외래 복막투석 소아에서 리네졸리드로 치료한 반코마이신 내성 장구균 복막염 1례김성도, 박성신, 백승아, 조병수대한소아신장학회 · Childhood Kidney Diseases2008 · 제12권 제2호소아 환아에서 분리된 Vancomycin 내성 장구균에 대한 임상적 고찰김동수, 박은숙, 이경원, 이경재, 이동우, 장광천대한소아감염학회 · Pediatric Infection and Vaccine2001 · 제8권 제2호반코마이신 저항 장구균의 자발적 집락 소실 기간에 대한 영향 인자김기환, 김동수, 이제선대한소아감염학회 · Pediatric Infection and Vaccine2015 · 제22권 제1호신생아에서의 Vancomycin 용량 가이드라인 적절성 평가김은경, 도현정, 윤인경, 최경숙, 최창원, 남궁형욱, Eunkyung Euni Lee한국병원약사회 · 병원약사회지2016 · 제33권 제2호

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