紫河車가 수컷생쥐의 生殖能力에 미치는 影響
Effects of Hominis placenta on mice sperm motility and in vitro fertilization
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Abstract
Objective: This study was conducted to investigate the effects of Hominis placenta (紫河車) on the reproductive competence in male mice. Materials and Method: We administered the decoction of Hominis placenta to 8-week-old and 18-week-old male mice once a day for 8 days. And we observed the count, the motility and the morphology of epididymal sperm from the male mice and the result of in vitro fertilization and embryonic development of oocytes. We examined the pregnancy rate and the delivery rate from the mice. Results: It was effective to be treated with Hominis placenta on the increase of the count and the motility of epididymal sperm in 8-week old mice but not effective on the change of the morphology of that. It was effective to be treated with Hominis placenta on the increase of the motility of epididymal sperm in 18-week old mice but not effective on the increase of the count and the change of the morphology of that. There was no signigicant effectiveness in the rate of in vitro fertilization and embryonic development of oocytes of the Hominis placenta treated group and that of control group in 8-week and 18-week old mice. There was no signigicant effectiveness in the rate of pregnancy and delivery of in vitro cultured blastocyst from mice of the Hominis placenta treated group and that of control group in 8-week and 18-week old mice. Conclusion: This study shows that Hominis placenta has no significant effects on the morphology of epididymal sperm from the male mice and in vitro fertilization and embryonic development of oocytes but has significant effects on the count and motility. We can suggest that Hominis placenta has an effect on the improvement of reproductive competence in male mice.
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