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猪蹄와 通乳湯去穿山甲이 白鼠의 乳汁分泌에 미치는 影響

Effect of Jeoje and Tongyu-tang except Cheonsangap on lactation in postpartum rat

장준복|조정훈|이경섭|김성보
대한한방부인과학회 (The Society Of Oriental Obstetrics & Gynecology)|2004.05|대한한방부인과학회지 (The Journal of Oriental Obstetrics ＆ Gynecology)|제17권 제2호|pp. 27-40

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초록

Abstract

Objective: This study was conducted to investigate the effect of Jeoje( 蹄) and Tongyu-tang except Chunsangap on lactation in postpartum rat. Material and Method: We used 18 weeks pregnant Spraque Dawley rats and administered the decotions of Jeoje and Tongyu-tang except Cheonsangap to rats (treated group) and normal saline to control group once in a day for 4days and 8days. Then we observed the changes of the body weight changes of postpartum rats and pup rats, level of serum prolactin, -casein m-RNA, WAP m-RNA and mammary gland tissue of postpartum rats. Result: We found that the body weight changes of postpartum rats and pup rats and the level of serum prolactin in Jeoje treated group and Tongyu-tang except Chunsangap treated group showed no significant difference. In the level of -casein and WAP gene, Jeoje treated group and Tongyu-tang except Chunsangap treated group increased than control group. Mammary gland tissue of Jeoje treated group and Tongyu-tang except Chunsangap treated group showed significantly increased angiogenesis of blood vessle compared with the control group. Conclusion: This study shows that Jeoje and Tongyu-tang except Chunsangap have an effect on lactation in postpartum rat. But the mechanism of it may be other way than the hormon pathway.

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