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子가 웅성 백서의 정소기능 및 catalase와 peroxidase의 활성에 미치는 영향

Effects of Allii tuberosi Semen on the testicular function, the activity of catalase and peroxidase in male Rat

백승희|박창건
대한한방부인과학회 (The Society Of Oriental Obstetrics & Gynecology)|2004.08|대한한방부인과학회지 (The Journal of Oriental Obstetrics ＆ Gynecology)|제17권 제3호|pp. 72-81

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참고문헌

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Abstract

Objective : Allii tuberosi Semen has been used to treat impotence, nocturnal emission, enuresis, lumbago, leukorrhea etc. The aim of this study was to investigate the effects of Allii tuberosi Semen on testicular tissues and to evaluate Allii tuberosi Semen on treatment male infertility caused by azoospermia or oligozoospermia. Methods : To investigate the effects of Allii tuberosi Semen on testis and spermatogenesis, male rats were administered Allii tuberosi Semen extract for 28 days. We assayed total sperm concentration, morphologically normality, motility, activity of catalase and peroxidase from the testis in male rats at 28 days afterwards. Results : 1) Total sperm concentration, morphologically normality and motility showed significant increase in male rat administered with Allii tuberosi Semen extract for 28 days. 2) It was observed that spermatogenesis has developed with vigor from testicular tissues in male rat administered with Allii tuberosi Semen. 3) Activity of peroxidase showed significant increase in male rat administered with Allii tuberosi Semen. Conclusion : These results indicate the effects of Allii tuberosi Semen on testicular function, activity of peroxidase in male rat. We suggested that Allii tuberosi Semen is an appropriate herbal medicine to treat medicaly male infertility caused by oligozoospermia or azoospermia.

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  43. "Male infertility and the genetics of spermatogenesis", 62(6), pp.1274~1281 (1998)
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  51. "中醫男科臨床治療學", pp.206~15 (1991), 人民衛生出版社
  52. "Y chromosome microdeletions and alterations of spermatogenesis", 22(2), pp.226~239 (2001)
  53. "備急千金要方", pp.16~8 (1988), 一中社
  54. "六科證治準繩", pp.279~287 (1992), 大星文化社
  55. "婦人大全良方", pp.293~4 (1992), 一中社
  56. "實用中醫腎病學", pp.786~95 (1990), 上海中醫學院出版社
  57. "東國韓醫學硏究所論文集", 3, pp.151~62 (1994)
  58. "新藥品植物學", pp.227~ (1997), 學窓社
  59. "原色韓國藥用植物圖鑑", pp.48~ (1989), 아카데미書籍
  60. "原色臨床本草學", pp.204~ (1988), 永林社
  61. "中醫百家藥論 萃", pp.613~ (1993), 中廣出版社
  62. "中華臨床中藥學", pp.1685~ (1998), 人民衛生出版社
  63. "Relation between indices of semen analysis and pregnancy rate in infertile couples", 28(12), pp.1314~9 (1977)
  64. "The duration of infertility an important datum for the fertility prognosis of men with semen abnormalities", pp.423~5 (1978)
  65. "Effect of sperm morphology and motile sperm count on outcome of intrauterine insemination in oligozoospermia and", or asthenozoospermia, 1990, pp.53(5), 892~7
  66. "Correlation of semen variables and pregnancy rates for donor insemination", pp.355~9 (1994)
  67. "Failure of fertilization in in vitro fertilization J In Vitro Fert Embryo Transf"
  68. "The biology of oxygen radicals", 201(4359), pp.875~80 (1978)
  69. "Free-radical mechanisms in tissue injury", 222(1), pp.1~15 (1984)
  70. "Oxygen and toxicity inhibition of amino acid biosynthesis", 262(5567), pp.418~20 (1976)
  71. "Hydrogen peroxide mediates the toxic effect of oxygen radicals on human fibroblasts", 80(1), pp.45~ (1981)
  72. "Role of oxidative stress and antioxidants in male infertility", 16(6), pp.464~481 (1995)
  73. "Role of oxidative stress and antioxidants in male infertility", 16(6), pp.464~481 (1995)

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