경구 처방의 경피용 제제 및 한방 화장품 소재 개발 시의 방제이론 적용에 관한 연구
A Study on Application of Korean Medical Prescriptions Theory in Developing Transdermal Medicine and Korean Medical Cosmetic Preparation Using Oral Herbal Medicine
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Objectives: To identify whether Sovereign-Minister-Assistant-Courier (君臣佐使) Theory and Meridian Tropism (歸經) Theory of oral herbal medicine can be applied to trans-dermal medicine and whether pharmaceutical efficacy can be delivered to skin by Courier herb (使藥). Methods: We reviewed previous studies related to Sovereign-Minister-Assistant-Courier Theory. And we examined whether prescription compositions based on Sovereign- Minister-Assistant-Courier Theory correspond with efficacy results of trans-dermal medicine experimentally identified. Results: When Sovereign-Minister-Assistant-Courier Theory is applied to trans-dermal medicine, Courier herb act as delivering the effective components to the lesion penetrating skin barrier. And we identified that medicine absorbed through the digestive processes may not correspond with Courier herb applied topically. Conclusions: We identified that Courier herb act as delivering the effective components to the lesion. But to strength evidences, additional studies on this action will be needed.
Abstract
Objectives: To identify whether Sovereign-Minister-Assistant-Courier (君臣佐使) Theory and Meridian Tropism (歸經) Theory of oral herbal medicine can be applied to trans-dermal medicine and whether pharmaceutical efficacy can be delivered to skin by Courier herb (使藥). Methods: We reviewed previous studies related to Sovereign-Minister-Assistant-Courier Theory. And we examined whether prescription compositions based on Sovereign- Minister-Assistant-Courier Theory correspond with efficacy results of trans-dermal medicine experimentally identified. Results: When Sovereign-Minister-Assistant-Courier Theory is applied to trans-dermal medicine, Courier herb act as delivering the effective components to the lesion penetrating skin barrier. And we identified that medicine absorbed through the digestive processes may not correspond with Courier herb applied topically. Conclusions: We identified that Courier herb act as delivering the effective components to the lesion. But to strength evidences, additional studies on this action will be needed.
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