유방염의 침구 치료에 대한 체계적 문헌고찰
The Effectiveness of Acupuncture and Moxibustion Treatment for Mastitis: A Systematic Review
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목적 : 유방염의 침구치료 효과에 대한 연구를 목적으로 한다. 방법 : Embase, PubMed, CNKI 를 포함한 총 10개의 검색 엔진을 사용하였으며, 검색어는 “유방염” and “침”, “유선염” and “침”, "유방염" and "뜸" 등을 사용하였다. 문헌 선정 과정에서 침구 치료의 효과를 판정하는데 큰 영향을 미치는 치료법을 병행한 연구, 대조군이 항생제가 아닌 연구는 배제하였다. 논문의 질 평가는 Risk of Bias를 통해 이루어졌다. 또한 항생제와 비교한 침구 치료의 총 유효율을 알아보기 위해 Review manager를 이용하여 메타 분석을 시행하였다. 결과 : 무작위 배정 임상연구만을 선정하였으며, 총 6건의 연구가 최종적으로 선발되었다. 2건의 연구에서 침구 치료군의 총유효율이 유의하게 높았으나, 다른 3건의 연구는 유의한 차이를 보이지 않았다. 한편 3건의 연구로 메타 분석을 시행한 결과, 항생제와 침구치료의 총유효율에서 유의미한 차이가 없었다. 결론 : 6건의 RCT를 분석한 결과, 침구 치료는 유방염의 치료법 중 하나로서 가능성을 가지고 있는 것으로 보인다. 그러나 선정된 문헌의 수가 적어 그 효과를 명시하기에는 부족함이 있었으며, 향후 더 정밀하고 질 높은 연구가 필요할 것으로 보인다.
Abstract
Objectives: The purpose of this study is to investigate the effectiveness of acupuncture and moxibustion for mastitis. Methods: We used ten databases including Embase, PubMed, and CNKI to investigate the literatures of mastitis using the keywords “mastitis” and “acupuncture”, “breast inflammation” and “acupuncture”, “mastitis” and “needle”, “breast inflammation” and “needle”, “mastitis” and “moxibustion”. We excluded studies which included treatments that could affect the judgement of the effectiveness of acupuncture treatment, and the control group was limited to antibiotics. The quality of the paper was evaluated by Risk of Bias. A meta-analysis was performed using a “Review manager” to see the effectiveness of acupuncture and moxibustion compared to antibiotics. Results: Only six RCT were finally selected. Five studies use the total effective rate as a evaluating index, and it was significantly higher than that of the control group in two studies. In other three studies, acupuncture showed similar effectiveness to antibiotics. Meta-analysis was performed through three studies, there was no statistically significant difference in total effective rate between acupuncture and antibiotic treatment. Conclusions: Analysis of six RCT showed that acupuncture and moxibustion seem to have many possibilities as one of the treatments for mastitis. However the number of documents is not sufficient, more research should be done to obtain reliable information.
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