세균성 질증의 한방외치요법에 대한 무작위 대조군 비교 임상시험 중심의 고찰
Analysis for Randomized Controlled Clinical Trials of Korean Medicine External Treatment on Bacterial Vaginosis
2
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Objectives: The purpose of this study was to show effectiveness of Korean medicine external treatment on bacterial vaginosis by analyzing randomized controlled clinical trials. Methods: We searched randomized controlled clinical trials related with Korean external treatment on bacterial vaginosis through national and overseas database and analyzed them in detail. Results: 15 articles were included according to our selection criteria and 2,176 women were involved. 1. All treatment groups were treated with intervention including Korean medicine external treatment and their results were statistically more effective than control groups. 2. External washing was the most frequently used method followed by vaginal tablet, fumigation and powder. 3. The most frequently used herbal medicine was Sophorae Radix followed by Phellodendri Cortex, Cindi Fructus, Dictamni Radicix Cortex and Kochiae Fructusa. 4. There were 4 studies reporting side effects of treatment and no significant side effects were observed. Conclusions: There was significant difference in the effectiveness of the intervention including Korean external therapy. Based on the analysis, it could be an effective way for the treatment of bacterial vaginosis in clinical practice.
Abstract
Objectives: The purpose of this study was to show effectiveness of Korean medicine external treatment on bacterial vaginosis by analyzing randomized controlled clinical trials. Methods: We searched randomized controlled clinical trials related with Korean external treatment on bacterial vaginosis through national and overseas database and analyzed them in detail. Results: 15 articles were included according to our selection criteria and 2,176 women were involved. 1. All treatment groups were treated with intervention including Korean medicine external treatment and their results were statistically more effective than control groups. 2. External washing was the most frequently used method followed by vaginal tablet, fumigation and powder. 3. The most frequently used herbal medicine was Sophorae Radix followed by Phellodendri Cortex, Cindi Fructus, Dictamni Radicix Cortex and Kochiae Fructusa. 4. There were 4 studies reporting side effects of treatment and no significant side effects were observed. Conclusions: There was significant difference in the effectiveness of the intervention including Korean external therapy. Based on the analysis, it could be an effective way for the treatment of bacterial vaginosis in clinical practice.
참고문헌 (34)
- Hill GB, "The microbiology of bacterial vaginosis", American Journal of Obstetrics and Gynecology, 169(2 Pt 2), pp.450~454 (1993)
- Nyirjesy P, "Vulvovaginal candidiasis and bacterial vaginosis", Infectious Disease Clinics of North America, 22(4), pp.637~652 (2008)
- Korean Society of Obsterics and Gynecology, "Gynecology", pp.148~149 (2015), Korea Medical Book Publishing Company (KOMB)
- Moon WS, "A Historical Consideration on the External Treatment theories and diseases for which medicine is efficacious", Korean Journal of Oriental Medicine, 10(2), pp.1~21 (2014)
- 허경자, "婦人科疾患의 外治療法에 관한 연구(1)", 대한한의학원전학회지, 20(2), pp.31~51 (2007), 대한한의학원전학회
- Jin CS, "A Study on the Washing Methods of the External Treatment Used in the Treatment of Pruritus", J Korean Obstet Gynecol, 11(2), pp.269~289 (1998)
- 성현아, "蛇床子洗方의 Gardnerella vaginalis에 대한 시험관 내 항균력 및 Metronidazole과 병용효과", 대한한방부인과학회지, 23(2), pp.20~37 (2010), 대한한방부인과학회
- 권지명, "淸帶湯의 Gardnerella vaginalis에 대한 시험관내 항균력 및 Clindamycin과의 병용효과", 대한한방부인과학회지, 24(2), pp.1~12 (2011), 대한한방부인과학회
- 오자영, "加減攝營煎의 Gardnerella vaginalis에 대한 시험관내 항균력 및 Clindamycin과의 병용효과", 대한한방부인과학회지, 27(1), pp.65~80 (2014), 대한한방부인과학회[DOI]
- 이승혜, "完帶湯의 Gardnerella vaginalis에 대한 시험관내 항균력 및 Clindamycin과 병용효과", 대한한방부인과학회지, 25(1), pp.34~46 (2012), 대한한방부인과학회
- 장경호, "Gardnerella vaginalis에 대한 牧丹皮, 蘇木, 魚腥草, 連翹, 夏枯草, 玄蔘의 항균효과", 동의생리병리학회지, 19(4), pp.1016~1021 (2005), 한의병리학회
- 백선은, "위축성 질염의 좌훈 치료 연구에 관한 체계적 문헌 고찰", 대한한방부인과학회지, 29(1), pp.92~101 (2016), 대한한방부인과학회[DOI]
- 박경덕, "진균성 질염의 한약 훈증 치료에 대한 체계적 문헌 고찰", 대한한방부인과학회지, 31(3), pp.20~32 (2018), 대한한방부인과학회[DOI]
- Li XM, "Therapeutic effect of Chinese herbal extracts on bacterial vaginosis in pregnant women(复方中药提取物治疗孕妇细菌性阴道炎的疗效观察)", Journal of Henan University(Medical Science), 22(4), pp.60~ (2003)
- Wang ML, "Therapeutic effect of traditional Chinese medicine combined with external washing and bathing on bacterial vaginosis(中药内服配合外洗坐浴治疗细菌性阴道病的疗效观察)", Chinese Journal of Modern Drug Application, 3(19), pp.109~110 (2009)
- Liu Y, "Treatment of 120 Cases of Bacterial Vaginosis with Chinese Herbal Lotion Combined with Compound Seabuckthorn Seed Oil(中药洗剂联合复方沙棘籽油栓治疗细菌性阴道病120例)", Traditional Chinese Medicinal Research, 23(11), pp.42~44 (2010)
- Wu Y, "Therapeutic effect of traditional Chinese medicine combined with external washing in the treatment of bacterial vaginosis(中药内服外洗治疗细菌性阴道病疗效观察)", Shanxi Journal of Traditional Chinese Medicine, 27(2), pp.20~21 (2011)
- Li ZY, "Observation on 40 Cases of Recurrent Bacterial Vaginosis Treated by Internal and External Treatment of Traditional Chinese Medicine(中药内外合治复发性细菌性阴道病40例观察)", Journal of Practical Traditional Chinese Medicine, 29(7), pp.544~ (2013)
- Liu JH, "Clinical observation on treating BV in TCM", Clinical Journal of Chinese Medicine, 5(22), pp.83~84 (2013)
- Tan WJ, "Clinical Observation on Treatment of Recurrent Bacterial Vaginosis with External Therapy of Traditional Chinese Medicine(中药内服外用合治痰湿瘀滞型复发性细菌性阴道病临床观察)", Guangxi Journal of Traditional Chinese Medicine, 39(6), pp.22~24 (2016)
- Ji ZF, "Treating 62 cases of bacterial vaginosis in TCM", Clinical Journal of Chinese Medicine, 9(19), pp.125~126 (2017)
- Zhao X, "Clinical Observation on the Treatment of Bacterial Vaginitis with Liuwei dihuang-tang, Chinese Herbal Fumigation and Washing(六味地黄汤和中药熏洗配合治疗细菌性阴道炎临床疗效观察)", World Latest Medicne Information, 17(65), pp.126~ (2017)
- Zhang Q, "Clinical Observation on Treatment of 60 Cases of Bacterial Vaginosis with External Washing of Traditional Chinese Medicine and Metronidazole(中药外洗联合甲硝唑治疗细菌性阴道病60例)", Shanxi Journal of Traditional Chinese Medicine, 31(11), pp.1456~1457 (2010)
- Ding LL, "Therapeutic effect of self-made traditional Chinese medicine external washing combined with metronidazole on 156 cases of bacterial vaginosis(自制中药外洗方联合甲硝唑治疗细菌性阴道病156例疗效观察)", Guiding Journal of Traditional Chinese Medicine and Pharmacy, 17(12), pp.42~43 (2011)
- Zhou YP, "Treatment of 43 Cases of Bacterial Vaginosis with External Washing of Traditional Chinese Medicine and Western Medicine(中药外洗联合西药治疗细菌性阴道病43例)", Chinese Journal of Traditional Medical Science and Technology, 19(3), pp.242~ (2012)
- Cao ZF, "Treatment of 88 Cases of Bacterial Vaginosis with External Washing of Traditional Chinese Medicine and Metronidazole(中药外洗联合甲硝唑治疗细菌性阴道病88例)", Chinese Medicine Modern Distance Education of China, 12(10), pp.58~ (2014)
- Zhao LQ, "Therapeutic effect of Liuweidihuang-tang combined with traditional Chinese medicine fumigation on bacterial vaginitis(六味地黄汤联合中药熏洗治疗细菌性阴道炎疗效观察)", Journal of New Chinese Medicine, 47(10), pp.103~104 (2015)
- Hu YF, "Efficacy of six ingredient rehmannia decoction combined with Chinese herb fumigation washing in the treatment of bacterial vaginitis", Chinese Medicine and Pharmacy, 7(12), pp.15~18 (2017)
- 조성남, "난치성 질염의 최신 치료법", Obstetrics & Gynecology Science, 48(2), pp.261~268 (2005), 대한산부인과학회
- 최정실, "가임기 여대생의 생식기 관련 개인위생과 세균성 질염 발생의 위험요인", 가정간호학회지, 25(1), pp.87~95 (2018), 한국가정간호학회[DOI]
- 유내, "질염 환자에서 다중 PCR을 이용한 배양이 까다로운 미생물 검출의 임상적 유용성", Annals of Clinical Microbiology, 14(1), pp.30~35 (2011), 대한임상미생물학회
- 김정숙, "여성청결제 사용 실태와 만족도에 대한 연구", 아시안뷰티화장품학술지, 13(2), pp.267~274 (2015), 한국피부과학연구원
- The complication committee of Herbology, "Herbology", pp.221~227 (2008), Younglim publisher
- Chen ZJ, "Analysis of the Oxidative Stress Status in Nonspecific Vaginitis and Its Role in Vaginal Epithelial Cells Apoptosis", BioMed Research International, 2015, pp.1~7 (2015)
