Distal acquired demyelinating symmetric neuropathy associated with anti-GM1 and anti-GD1b antibodies
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Distal acquired demyelinating symmetric (DADS) neuropathy is a variant form of chronic inflammatory demyelinating polyradiculoneuropathy. A 54-year-old man presented with gait disturbance owing to weakness in both legs. Nerve conduction studies showed demyelinating sensorimotor polyneuropathy, and laboratory studies demonstrated anti-GM1 and anti-GD1b IgG antibodies, but no anti-myelin associated glycoprotein activity. We suggest that an antiganglioside antibodies assay needs to be applied when DADS neuropathy is suspected in order to improve the classification of dysimmune neuropathies.
Abstract
Distal acquired demyelinating symmetric (DADS) neuropathy is a variant form of chronic inflammatory demyelinating polyradiculoneuropathy. A 54-year-old man presented with gait disturbance owing to weakness in both legs. Nerve conduction studies showed demyelinating sensorimotor polyneuropathy, and laboratory studies demonstrated anti-GM1 and anti-GD1b IgG antibodies, but no anti-myelin associated glycoprotein activity. We suggest that an antiganglioside antibodies assay needs to be applied when DADS neuropathy is suspected in order to improve the classification of dysimmune neuropathies.
참고문헌 (10)
- Barohn RJ, "Chronic inflammatory demyelinating polyradiculoneuropathy. Clinical characteristics, course, and recommendations for diagnostic criteria", Arch Neurol, 46, pp.878~884 (1989)
- Katz JS, "Distal acquired demyelinating symmetric neuropathy", Neurology, 54, pp.615~620 (2000)
- Dimachkie MM, "Multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, and other chronic acquired demyelinating polyneuropathy variants", Neurol Clin, 31, pp.533~555 (2013)
- O’Leary CP, "The role of antiglycolipid antibodies in peripheral neuropathies", Curr Opin Neurol, 13, pp.583~588 (2000)
- Larue S, "Non-anti-MAG DADS neuropathy as a variant of CIDP: clinical, electrophysiological, laboratory features and response to treatment in 10 cases", Eur J Neurol, 18, pp.899~905 (2011)
- Remiche G, "Distal acquired demyelinating symmetric neuropathy associated with anti-GM1 antibodies:is this a CIDP variant?", Acta Neurol Belg, 110, pp.103~106 (2010)
- Saperstein DS, "Clinical spectrum of chronic acquired demyelinating polyneuropathies", Muscle Nerve, 24, pp.311~324 (2001)
- Nobile-Orazio E, "Frequency and clinical correlates of anti-neuronal IgM antibodies in neuropathy associated with IgM monoclonal gammopathy", Ann Neurol, 36, pp.416~424 (1994)
- Quarles RH, "Autoantibodies associated with peripheral neuropathy", Muscle Nerve, 22, pp.800~822 (1999)
- Rinaldi S, "Ganglioside antibodies and neuropathies", Curr Opin Neurol, 21, pp.540~546 (2008)