유전자변형 형광제브라피쉬의 생태계 위해성평가에 관한 연구
The Study on Ecological Assessment of Living Modified Fluorescent Zebrafish, Danio rerio
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Abstract
This study reviews the concept and process of ecological risk assessment on Living Modified Organisms (LMOs) under the Cartagena Protocol on Biodiversity and tries to set the direction of the ecological risk assessment on LM fluorescent zebrafish, Dania rerio, which may be soon filed for market approval in Korea.It is expected that our country would ratify the Protocol in the near future. In this case, the Transboundary Movement of LMOs Act comes into effect 3 months after the ratification, and then all LMOs should be used through risk assessment in accordance with the Act.LMOs is one of good items traded between countries so that the risk assessment should be harmonized with international standards. Thus, the ecological risk assessment on LM fluorescent zebrafish in Korea needs to observe the process of risk assessment prescribed in the Protocol, which consists of hazard identification, evaluation of likelihood, evaluation of consequence, estimation of risk, and determination of risk.The ecological risk assessment on living modified fishes is still at an early stage, and a variety of pathways between hazards and harmful effects in ecosystem were not well identified. For this reason, the cases of harmful effects previously posed by aquaculture fishes and invasive species need to be considered in order to facilitate the identification of harmful effects that may be potentially caused by LMOs. In addition, it is reported that zebrafish has been established in Japan and USA, but there is no official risk assessment report on this LM fish published by any government authorities in the world. Therefore, the possibility of passing winter of this fish is a major concern in terms of prevention of establishment and the matter should be clearly evaluated.
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