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Neurological aspects of anhidrosis: differential diagnoses and diagnostic tools

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초록

Anhidrosis refers to the condition in which the body does not respond appropriately to thermal stimuli by sweating. Sweating plays an important role in maintaining the body temperature, and its absence should not be overlooked since an elevated body temperature can cause various symptoms, even leading to death when uncontrolled. The various neurological disorders that can induce anhidrosis make a detailed neurological evaluation essential. The medication history of the patient should also be checked because anhidrosis can be caused by various drugs. The tests available for evaluating sweating include the quantitative sudomotor axon reflex sweat test, thermoregulatory sweat test, sympathetic skin response, and electrochemical skin conductance. Pathological findings can also be checked directly in a skin biopsy. This review discusses the differential diagnosis and evaluation of anhidrosis.

Abstract

Anhidrosis refers to the condition in which the body does not respond appropriately to thermal stimuli by sweating. Sweating plays an important role in maintaining the body temperature, and its absence should not be overlooked since an elevated body temperature can cause various symptoms, even leading to death when uncontrolled. The various neurological disorders that can induce anhidrosis make a detailed neurological evaluation essential. The medication history of the patient should also be checked because anhidrosis can be caused by various drugs. The tests available for evaluating sweating include the quantitative sudomotor axon reflex sweat test, thermoregulatory sweat test, sympathetic skin response, and electrochemical skin conductance. Pathological findings can also be checked directly in a skin biopsy. This review discusses the differential diagnosis and evaluation of anhidrosis.

참고문헌 (41)

  1. Chia KY, "Approach to hypohidrosis", J Eur Acad Dermatol Venereol, 27, pp.799~804 (2013)
  2. Munetsugu T, "Revised guideline for the diagnosis and treatment of acquired idiopathic generalized anhidrosis in Japan", J Dermatol, 44, pp.394~400 (2017)
  3. Sato K, "Biology of sweat glands and their disorders. I. normal sweat gland function", J Am Acad Dermatol, 20, pp.537~563 (1989)
  4. Folk GE Jr, "The evolution of sweat glands", Int J Biometeorol, 35, pp.180~186 (1991)
  5. Low PA, "Testing the autonomic nervous system", Semin Neurol, 23, pp.407~421 (2003)
  6. Cheshire WP, "Drug-induced hyperhidrosis and hypohidrosis:incidence, prevention and management", Drug Saf, 31, pp.109~126 (2008)
  7. Wenning GK, "Multiple system atrophy", Lancet Neurol, 3, pp.93~103 (2004)
  8. Sandroni P, "Autonomic involvement in extrapyramidal and cerebellar disorders", Clin Auton Res, 1, pp.147~155 (1991)
  9. Lipp A, "Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure", Arch Neurol, 66, pp.742~750 (2009)
  10. Thaisetthawatkul P, "Autonomic dysfunction in dementia with Lewy bodies", Neurology, 62, pp.1804~1809 (2004)
  11. Korpelainen JT, "Ipsilateral hypohidrosis in brain stem infarction", Stroke, 24, pp.100~104 (1993)
  12. Davis SL, "Thermoregulation in multiple sclerosis", J Appl Physiol, 109, pp.1531~1537 (2010)
  13. Allen DR, "Impaired sweating responses to a passive whole body heat stress in individuals with multiple sclerosis", J Neurophysiol, 118, pp.7~14 (2017)
  14. Singer W, "Pure autonomic failure: predictors of conversion to clinical CNS involvement", Neurology, 88, pp.1129~1136 (2017)
  15. Tesfaye S, "Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments", Diabetes Care, 33, pp.2285~2293 (2010)
  16. Fealey RD, "Thermoregulatory sweating abnormalities in diabetes mellitus", Mayo Clin Proc, 64, pp.617~628 (1989)
  17. Zochodne DW, "Autonomic involvement in Guillain-Barré syndrome:a review", Muscle Nerve, 17, pp.1145~1155 (1994)
  18. Anandan C, "Prevalence of autonomic dysfunction in hospitalized patients with Guillain-Barré syndrome", Muscle Nerve, 56, pp.331~333 (2017)
  19. Manganelli F, "Autoimmune autonomic ganglionopathy: a possible postganglionic neuropathy", Arch Neurol, 68, pp.504~507 (2011)
  20. Iodice V, "Efficacy of immunotherapy in seropositive and seronegative putative autoimmune autonomic ganglionopathy", Neurology, 72, pp.2002~2008 (2009)
  21. Li Y, "Clinical experience of seropositive ganglionic acetylcholine receptor antibody in a tertiary neurology referral center", Muscle Nerve, 52, pp.386~391 (2015)
  22. Ohnishi A, "Denervation of eccrine glands in patients with familial amyloidotic polyneuropathy type I", Neurology, 51, pp.714~721 (1998)
  23. Tugnoli V, "Hyperhidrosis and sympathetic skin response in chronic alcoholic patients", Clin Auton Res, 9, pp.17~22 (1999)
  24. Hilz MJ, "Assessment and evaluation of hereditary sensory and autonomic neuropathies with autonomic and neurophysiological examinations", Clin Auton Res, 12(Suppl 1), pp.I33~I43 (2002)
  25. Verrecchia E, "The impact of fever", hyperthermia in the diagnosis of Fabry: a retrospective analysis, 2016, pp.32, 26~30
  26. Weller M, "Tonic pupil, areflexia, and segmental anhidrosis: two additional cases of Ross syndrome and review of the literature", J Neurol, 239, pp.231~234 (1992)
  27. Chen YC, "Identification of subgroups of acquired idiopathic generalized anhidrosis", Neurologist, 14, pp.318~320 (2008)
  28. Nakazato Y, "Idiopathic pure sudomotor failure: anhidrosis due to deficits in cholinergic transmission", Neurology, 63, pp.1476~1480 (2004)
  29. Phillip A. Low, "Autonomic Function Tests: Some Clinical Applications Open Access", Journal of Clinical Neurology, 9(1), pp.1~8 (2013), 대한신경과학회[DOI]
  30. Low PA, "Evaluation of sudomotor function", Clin Neurophysiol, 115, pp.1506~1513 (2004)
  31. Sletten DM, "Relationship of Q-sweat to quantitative sudomotor axon reflex test (QSART) volumes", Muscle Nerve, 41, pp.240~246 (2010)
  32. Illigens BM, "Sweat testing to evaluate autonomic function", Clin Auton Res, 19, pp.79~87 (2009)
  33. Elie B, "Sympathetic skin response: normal results in different experimental conditions", Electroencephalogr Clin Neurophysiol, 76, pp.258~267 (1990)
  34. Gibbons C, "The evaluation of small fiber function-autonomic and quantitative sensory testing", Neurol Clin, 22, pp.683~702 (2004)
  35. Casellini CM, "Sudoscan, a noninvasive tool for detecting diabetic small fiber neuropathy and autonomic dysfunction", Diabetes Technol Ther, 15, pp.948~953 (2013)
  36. Buchmann SJ, "Assessment of sudomotor function", Clin Auton Res (2018)[DOI]
  37. Novak P, "Electrochemical skin conductance: a systematic review", Clin Auton Res (2017)[DOI]
  38. Lauria G, "European Federation of Neurological Societies", Peripheral Nerve Society Guideline on the use of skin biopsy in the diagnosis of small fiber neuropathy. Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society, 2010, pp.17, 903~912
  39. Chan AC, "Small fiber neuropathy: getting bigger!", Muscle Nerve, 53, pp.671~682 (2016)
  40. Eun Hee Sohn, "Skin biopsy: an emerging method for small nerve fiber evaluation", Annals of Clinical Neurophysiology, 20(1), pp.3~11 (2018), 대한임상신경생리학회[DOI]
  41. Tay LK, "Acquired idiopathic anhidrosis: a diagnosis often missed", J Am Acad Dermatol, 71, pp.499~506 (2014)

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