Alcohol, Smoking, Physical Activity, Protein, and Lower Urinary Tract Symptoms: Prospective Longitudinal Cohort
0
조회
0
다운로드
4
인용
0
참고문헌
키워드
초록
Purpose: To evaluate risk factors for deterioration of lower urinary tract symptoms (LUTS) in elderly men in a communitybased, prospective longitudinal cohort study. Methods: In a suburban area in Korea, 1,514 subjects aged ≥45 years were randomly selected by systematic sampling. A total of 918 elderly subjects were enrolled in this in-depth clinical study in 2004. Of these, 547 participants were followed up for 3 years and the data was analyzed in 2014. Standard questionnaires were administered face-to-face by trained interviewers. After excluding women, 224 male participants with complete data including transrectal ultrasonography were included in the final analysis. LUTS were diagnosed using the International Prostate Symptom Score (IPSS) questionnaire. Symptom deterioration was defined as a score of ≥8 points during the 3-year follow-up period. Results: LUTS prevalence increased to 13.1% and the mean IPSS increased by 2.6 points during the 3-year period. After adjusting for confounders, a smoking history of ≥50 pack-years was an independent risk factor for deterioration of LUTS and storage subsymptoms compared with no history of smoking (3.1 and 5.1 odds, respectively). Physical activity had a protective effect on voiding subsymptoms. However, high protein diet and alcohol intake were not associated with LUTS deterioration. Conclusions: The LUTS prevalence among elderly men living in a suburban area increased to 13.1% and the IPSS increased by 2.6 points during the 3-year period. A history of heavy smoking, low physical activity, and high protein intake were associated with LUTS deterioration. However, there was no significant association between alcohol intake and LUTS deterioration.
Abstract
Purpose: To evaluate risk factors for deterioration of lower urinary tract symptoms (LUTS) in elderly men in a communitybased, prospective longitudinal cohort study. Methods: In a suburban area in Korea, 1,514 subjects aged ≥45 years were randomly selected by systematic sampling. A total of 918 elderly subjects were enrolled in this in-depth clinical study in 2004. Of these, 547 participants were followed up for 3 years and the data was analyzed in 2014. Standard questionnaires were administered face-to-face by trained interviewers. After excluding women, 224 male participants with complete data including transrectal ultrasonography were included in the final analysis. LUTS were diagnosed using the International Prostate Symptom Score (IPSS) questionnaire. Symptom deterioration was defined as a score of ≥8 points during the 3-year follow-up period. Results: LUTS prevalence increased to 13.1% and the mean IPSS increased by 2.6 points during the 3-year period. After adjusting for confounders, a smoking history of ≥50 pack-years was an independent risk factor for deterioration of LUTS and storage subsymptoms compared with no history of smoking (3.1 and 5.1 odds, respectively). Physical activity had a protective effect on voiding subsymptoms. However, high protein diet and alcohol intake were not associated with LUTS deterioration. Conclusions: The LUTS prevalence among elderly men living in a suburban area increased to 13.1% and the IPSS increased by 2.6 points during the 3-year period. A history of heavy smoking, low physical activity, and high protein intake were associated with LUTS deterioration. However, there was no significant association between alcohol intake and LUTS deterioration.
참고문헌 (30)
- 김태헌, "The Prevalence of Lower Urinary Tract Symptoms in Korean Men Aged 40 Years or Older: A Population-Based Survey", International Neurourology Journal, 18(3), pp.126~132 (2014), 대한배뇨장애요실금학회
- Abrams P, "International Consultation on New Developments in Prostate Cancer and Prostate Diseases. Evaluation and treatment of lower urinary tract symptoms in older men", J Urol, 189(1 Suppl), pp.S93~S101 (2013)
- Wei JT, "Urologic diseases in america project: benign prostatic hyperplasia", J Urol, 179(1 Suppl), pp.S75~S80 (2008)
- McVary KT, "Update on AUA guideline on the management of benign prostatic hyperplasia", J Urol, 185, pp.1793~1803 (2011)
- Rohrmann S, "Association of cigarette smoking, alcohol consumption and physical activity with lower urinary tract symptoms in older American men: findings from the third National Health And Nutrition Examination Survey", BJU Int, 96, pp.77~82 (2005)
- 이호원, "The Study About Physical Activity for Subjects With Prevention of Benign Prostate Hyperplasia", International Neurourology Journal, 18(3), pp.155~162 (2014), 대한배뇨장애요실금학회
- Patel ND, "Epidemiology and etiology of benign prostatic hyperplasia and bladder outlet obstruction", Indian J Urol, 30, pp.170~176 (2014)
- Parsons JK, "Lifestyle factors, benign prostatic hyperplasia, and lower urinary tract symptoms", Curr Opin Urol, 21, pp.1~4 (2011)
- Parsons JK, "Alcohol consumption is associated with a decreased risk of benign prostatic hyperplasia", J Urol, 182, pp.1463~1468 (2009)
- Maserejian NN, "Are physical activity, smoking and alcohol consumption associated with lower urinary tract symptoms in men or women? Results from a population based observational study", J Urol, 188, pp.490~495 (2012)
- Parsons JK, "Physical activity, benign prostatic hyperplasia, and lower urinary tract symptoms", Eur Urol, 53, pp.1228~1235 (2008)
- Tavani A, "Intake of selected micronutrients and the risk of surgically treated benign prostatic hyperplasia: a case-control study from Italy", Eur Urol, 50, pp.549~554 (2006)
- Maserejian NN, "Dietary, but not supplemental, intakes of carotenoids and vitamin C are associated with decreased odds of lower urinary tract symptoms in men", J Nutr, 141, pp.267~273 (2011)
- Suzuki S, "Intakes of energy and macronutrients and the risk of benign prostatic hyperplasia", Am J Clin Nutr, 75, pp.689~697 (2002)
- Oh MJ, "Alcohol consumption shows a J-shaped association with lower urinary tract symptoms in the general screening population", J Urol, 187, pp.1312~1317 (2012)
- Homma Y, "Estimate criteria for diagnosis and severity in benign prostatic hyperplasia", Int J Urol, 3, pp.261~266 (1996)
- Lee HJ, "Development and validation of a computerized semi-quantitative food frequency questionnaire program for evaluating the nutritional status of the Korean elderly", Korean J Community Nutr, 7, pp.277~285 (2002)
- Levine M, "Criteria and recommendations for vitamin C intake", JAMA, 281, pp.1415~1423 (1999)
- O’Donnell M, "Urinary sodium and potassium excretion, mortality, and cardiovascular events", N Engl J Med, 371, pp.612~623 (2014)
- Kristal AR, "Dietary patterns, supplement use, and the risk of symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial", Am J Epidemiol, 167, pp.925~934 (2008)
- "Guideline for low-risk alcohol drinking" (2013)[URL]
- Bondy SJ, "Low-risk drinking guidelines: the scientific evidence", Can J Public Health, 90, pp.264~270 (1999)
- Kim D, "ffect of job and leisure time physical activity in the risk of colorectal cancer: a case-control study", 박사, pp.1997
- Ainsworth BE, "Compendium of physical activities: classification of energy costs of human physical activities", Med Sci Sports Exerc, 25, pp.71~80 (1993)
- Meigs JB, "Risk factors for clinical benign prostatic hyperplasia in a community-based population of healthy aging men", J Clin Epidemiol, 54, pp.935~944 (2001)
- Tahtinen RM, "Tammela TL, Tikkinen KA. Smoking and bladder symptoms in women", Obstet Gynecol, 118, pp.643~648 (2011)
- Narkiewicz K, "Cigarette smoking increases sympathetic outflow in humans", Circulation, 98, pp.528~534 (1998)
- Knuutinen A, "Smoking affects collagen synthesis and extracellular matrix turnover in human skin", Br J Dermatol, 146, pp.588~594 (2002)
- Mukamal KJ, "Alcohol consumption and risk for coronary heart disease in men with healthy lifestyles", Arch Intern Med, 166, pp.2145~2150 (2006)
- De Nunzio C, "The correlation between metabolic syndrome and prostatic diseases", Eur Urol, 61, pp.560~570 (2012)